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Vacation Rentals near Lake Keowee Marina

150 Keowee Marina Dr, Seneca, South Carolina 29672-4725
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    Seneca is popular with travelers just like you. Don’t let them get your perfect place first—book today!
    All 66 Rentals in Seneca
    Clemson Football, Graduation, Golf, Boat, Swim, Fish, Hike, Bike, Waterfalls1 / 46
    (7)Excellent
    8.4 miles from Lake Keowee Marina
    5 Bedrooms, 3 Bathrooms, Sleeps 15 Quick View
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    Perfect Lake Hartwell Getaway.  Right On The Water, 12 Minutes From Campus1 / 28
    (41)Excellent
    4.8 miles from Lake Keowee Marina
    4 Bedrooms, 4 Bathrooms, Sleeps 8 Quick View
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    Private setting close to Clemson University1 / 20
    (26)Very good
    4.7 miles from Lake Keowee Marina
    3 Bedrooms, 2 Bathrooms, Sleeps 8 Quick View
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    Beautiful Lakefront Rental on Lake Keowee near Clemson. Pets welcome!1 / 14
    (71)Very good
    3.1 miles from Lake Keowee Marina
    4 Bedrooms, 3 Bathrooms, Sleeps 16 Quick View
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    Seneca, South Carolina
    Rental Home - 4 Bedrooms, 3 Bathrooms, Sleeps 16
    Tee House on BEAUTIFUL Lake Keowee1 / 25
    (26)Excellent
    0.6 miles from Lake Keowee Marina
    4 Bedrooms, 4 Bathrooms, Sleeps 8 Quick View
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    Seneca, South Carolina
    Rental Home - 4 Bedrooms, 4 Bathrooms, Sleeps 8
    7 mi from Clemson, 5000 square ft lake house, beach & deep water, 2 king suites1 / 22
    (151)Excellent
    0.2 miles from Lake Keowee Marina
    4 Bedrooms, 5 Bathrooms, Sleeps 11 Quick View
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    Seneca, South Carolina
    Rental Home - 4 Bedrooms, 5 Bathrooms, Sleeps 11
    Great Location! Close to town & amenities, just 10 miles from Clemson University1 / 42
    (88)Excellent
    1.3 miles from Lake Keowee Marina
    4 Bedrooms, 3 Bathrooms, Sleeps 12 Quick View
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    Seneca, South Carolina
    Rental Home - 4 Bedrooms, 3 Bathrooms, Sleeps 12
    Lakefront House Steps Away from Swimming, Boating, Kayaking & Relaxing1 / 50
    (32)Excellent
    4.7 miles from Lake Keowee Marina
    4 Bedrooms, 3 Bathrooms, Sleeps 11 Quick View
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    Seneca, South Carolina
    Rental Home - 4 Bedrooms, 3 Bathrooms, Sleeps 11
    The Cutt, Relaxing, private,  lake front paradise on stunning Lake Keowee in SC.1 / 46
    (17)Excellent
    4.5 miles from Lake Keowee Marina
    4 Bedrooms, 4 Bathrooms, Sleeps 12 Quick View
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    Seneca, South Carolina
    Rental Home - 4 Bedrooms, 4 Bathrooms, Sleeps 12
    Experience our Unique Modern Farmhouse; Quiet cove; 18 Private acres!1 / 43
    (54)Excellent
    2.0 miles from Lake Keowee Marina
    5 Bedrooms, 5 Bathrooms, Sleeps 18 Quick View
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    Seneca, South Carolina
    Rental Home - 5 Bedrooms, 5 Bathrooms, Sleeps 18
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    Easy access lake front W/  beach, waterfront patio and boat ramp1 / 32
    (118)Excellent
    5.3 miles from Lake Keowee Marina
    6 Bedrooms, 5 Bathrooms, Sleeps 14 Quick View
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    Seneca, South Carolina
    Rental Home - 6 Bedrooms, 5 Bathrooms, Sleeps 14
    Furnished apartment perfect for short term stay!1 / 8
    (33)Very good
    3.5 miles from Lake Keowee Marina
    1 Bedroom, 1 Bathroom, Sleeps 4 Quick View
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    Seneca, South Carolina
    Condo/Apartment - 1 Bedroom, 1 Bathroom, Sleeps 4
    Family getaway on lake near Clemson campus.1 / 26
    (29)Very good
    5.2 miles from Lake Keowee Marina
    4 Bedrooms, 3 Bathrooms, Sleeps 12 Quick View
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    Seneca, South Carolina
    Rental Home - 4 Bedrooms, 3 Bathrooms, Sleeps 12
    Beautiful Home on Lake Keowee- Deep Water Dock- 4bd/4ba -Close to Clemson1 / 29
    (45)Excellent
    1.6 miles from Lake Keowee Marina
    4 Bedrooms, 4 Bathrooms, Sleeps 15 Quick View
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    Seneca, South Carolina
    Rental Home - 4 Bedrooms, 4 Bathrooms, Sleeps 15
    Seneca Serenity.  The Ultimate Getaway on Lake Keowee!!1 / 43
    (25)Excellent
    1.8 miles from Lake Keowee Marina
    7 Bedrooms, 5 Bathrooms, Sleeps 24 Quick View
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    Seneca, South Carolina
    Rental Home - 7 Bedrooms, 5 Bathrooms, Sleeps 24
    Charming Keowee Lakeview Home - Near Clemson1 / 23
    (71)Excellent
    4.7 miles from Lake Keowee Marina
    3 Bedrooms, 3 Bathrooms, Sleeps 7 Quick View
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    Seneca, South Carolina
    Rental Home - 3 Bedrooms, 3 Bathrooms, Sleeps 7
    Fall fun at the cabin! Convenient to Lake Keowee and Clemson1 / 22
    (93)Very good
    2.1 miles from Lake Keowee Marina
    3 Bedrooms, 2 Bathrooms, Sleeps 8 Quick View
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    Seneca, South Carolina
    Rental Home - 3 Bedrooms, 2 Bathrooms, Sleeps 8
    **Beautiful Lake Keowee Home Sleeps 15 ** GET AWAY AND RELAX!!1 / 33
    (44)Excellent
    4.0 miles from Lake Keowee Marina
    5 Bedrooms, 4 Bathrooms, Sleeps 15 Quick View
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    Seneca, South Carolina
    Rental Home - 5 Bedrooms, 4 Bathrooms, Sleeps 15
    Lake Keowee Condo with Great Views! Near Clemson, Hiking and Waterfalls.1 / 16
    (33)Excellent
    0.6 miles from Lake Keowee Marina
    2 Bedrooms, 3 Bathrooms, Sleeps 6 Quick View
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    Seneca, South Carolina
    Condo/Apartment - 2 Bedrooms, 3 Bathrooms, Sleeps 6
    Panoramic Views, Best Location on Keowee, 150' of shoreline, 10 min. to Clemson1 / 24
    (71)Excellent
    1.9 miles from Lake Keowee Marina
    2 Bedrooms, 2 Bathrooms, Sleeps 4 Quick View
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    Seneca, South Carolina
    Rental Home - 2 Bedrooms, 2 Bathrooms, Sleeps 4
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    ' Estate on the Lake'! 7 BR/7 BA( 6 Suites)Over 8,400 Square Feet! Private Pool!1 / 50
    (131)Very good
    2.4 miles from Lake Keowee Marina
    7 Bedrooms, 7 Bathrooms, Sleeps 18 Quick View
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    • Private Outdoor Pool (Unheated)
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    Seneca, South Carolina
    Rental Home - 7 Bedrooms, 7 Bathrooms, Sleeps 18
    Comfortably Designed Lake Keowee Waterfront, Minutes to Clemson- In Seneca1 / 41
    (35)Excellent
    0.5 miles from Lake Keowee Marina
    5 Bedrooms, 4 Bathrooms, Sleeps 10 Quick View
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    Seneca, South Carolina
    Rental Home - 5 Bedrooms, 4 Bathrooms, Sleeps 10
    Beautiful Lake Views at Lake Keowee House1 / 34
    (36)Very good
    4.7 miles from Lake Keowee Marina
    3 Bedrooms, 3 Bathrooms, Sleeps 8 Quick View
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    Seneca, South Carolina
    Rental Home - 3 Bedrooms, 3 Bathrooms, Sleeps 8
    Lake Keowee lakefront 4 bedroom 3 bath home with dock, patio and fire pit.1 / 46
    (23)Very good
    4.5 miles from Lake Keowee Marina
    4 Bedrooms, 3 Bathrooms, Sleeps 10 Quick View
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    Seneca, South Carolina
    Rental Home - 4 Bedrooms, 3 Bathrooms, Sleeps 10
    Clemson/Lake Keowee Vacation Home for Family, Friends and Football Fans!1 / 30
    (57)Excellent
    1.4 miles from Lake Keowee Marina
    3 Bedrooms, 3 Bathrooms, Sleeps 8 Quick View
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    Seneca, South Carolina
    Rental Home - 3 Bedrooms, 3 Bathrooms, Sleeps 8
    NEW LISTING!  Newly Renovated Home with Private Beach and Amenities1 / 20
    (84)Excellent
    3.0 miles from Lake Keowee Marina
    4 Bedrooms, 4 Bathrooms, Sleeps 13 Quick View
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    Seneca, South Carolina
    Rental Home - 4 Bedrooms, 4 Bathrooms, Sleeps 13
    Lake Keowee Lakefront Home W/ Private Boat Ramp-Great Rates1 / 11
    (32)Excellent
    4.3 miles from Lake Keowee Marina
    3 Bedrooms, 3 Bathrooms, Sleeps 10 Quick View
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    Seneca, South Carolina
    Rental Home - 3 Bedrooms, 3 Bathrooms, Sleeps 10
    Beautiful 4/3, covered Dock,  2 Lrg.Covered Decks,  4.9 rating, $2400 mon/winter1 / 34
    (221)Excellent
    4.0 miles from Lake Keowee Marina
    4 Bedrooms, 3 Bathrooms, Sleeps 11 Quick View
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    Seneca, South Carolina
    Rental Home - 4 Bedrooms, 3 Bathrooms, Sleeps 11
    *Relaxed Cancelation Policy* Clemson Grads;CHRISTMAS;extended stay Duke Power1 / 32
    (12)Excellent
    4.6 miles from Lake Keowee Marina
    3 Bedrooms, 2 Bathrooms, Sleeps 6 Quick View
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    Seneca, South Carolina
    Rental Home - 3 Bedrooms, 2 Bathrooms, Sleeps 6
    Paradise on Lake Keowee1 / 14
    (21)Excellent
    1.1 miles from Lake Keowee Marina
    4 Bedrooms, 4 Bathrooms, Sleeps 7 Quick View
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    Seneca, South Carolina
    Rental Home - 4 Bedrooms, 4 Bathrooms, Sleeps 7
    Lake front home with dock, boat ramp and pool.  Minutes from downtown Clemson.1 / 49
    (33)Very good
    0.1 miles from Lake Keowee Marina
    5 Bedrooms, 3 Bathrooms, Sleeps 18 Quick View
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    Seneca, South Carolina
    Rental Home - 5 Bedrooms, 3 Bathrooms, Sleeps 18
    Clemson Families visit your college kids -avoid hotels Additional 10% discount!1 / 50
    (89)Excellent
    1.4 miles from Lake Keowee Marina
    4 Bedrooms, 4 Bathrooms, Sleeps 11 Quick View
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    Seneca, South Carolina
    Rental Home - 4 Bedrooms, 4 Bathrooms, Sleeps 11
    Clemson Game Ready!  5 Miles To Death Valley On Lake Hartwell. NO CLEANING FEES!1 / 17
    (25)Excellent
    7.6 miles from Lake Keowee Marina
    3 Bedrooms, 3 Bathrooms, Sleeps 6 Quick View
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    Seneca, South Carolina
    Rental Home - 3 Bedrooms, 3 Bathrooms, Sleeps 6
    500 feet of PRISTINE WATER FRONTAGE ON BEAUTIFUL LAKE KEOWEE1 / 36
    (60)Excellent
    1.9 miles from Lake Keowee Marina
    4 Bedrooms, 3 Bathrooms, Sleeps 10 Quick View
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    Seneca, South Carolina
    Rental Home - 4 Bedrooms, 3 Bathrooms, Sleeps 10
    Escape to the Lake - Luxury on Lake Keowee for large groups - SUMMER 20211 / 46
    (49)Excellent
    1.9 miles from Lake Keowee Marina
    9 Bedrooms, 7 Bathrooms, Sleeps 28 Quick View
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    Seneca, South Carolina
    Rental Home - 9 Bedrooms, 7 Bathrooms, Sleeps 28
    Beautiful Waterfront Retreat on Lake Keowee W/ Clemson  game day parking pass1 / 48
    (7)Excellent
    3.0 miles from Lake Keowee Marina
    2 Bedrooms, 2 Bathrooms, Sleeps 5 Quick View
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    Seneca, South Carolina
    Rental Home - 2 Bedrooms, 2 Bathrooms, Sleeps 5
    Football Weekends Available! 3 miles to CU.  Hartwell Waterfront, Pet friendly!1 / 23
    (110)Excellent
    5.2 miles from Lake Keowee Marina
    4 Bedrooms, 6 Bathrooms, Sleeps 10 Quick View
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    Seneca, South Carolina
    Rental Home - 4 Bedrooms, 6 Bathrooms, Sleeps 10
    Perfect weekend get away1 / 9
    (10)Excellent
    7.5 miles from Lake Keowee Marina
    2 Bedrooms, 1 Bathroom, Sleeps 6 Quick View
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    Seneca, South Carolina
    Rental Home - 2 Bedrooms, 1 Bathroom, Sleeps 6
    Clemson/Lake Hartwell house - big water views, dock, 10 minutes to Clemson1 / 24
    (38)Excellent
    6.5 miles from Lake Keowee Marina
    5 Bedrooms, 3 Bathrooms, Sleeps 14 Quick View
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    Seneca, South Carolina
    Rental Home - 5 Bedrooms, 3 Bathrooms, Sleeps 14
    3.5 miles from Lake Keowee Marina
    1 Bedroom, 1 Bathroom, Sleeps 2 Quick View
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    First floor one bedroom apartment with a large well-lit bedroom with queen bed, full bath, large living room with wood burning stove and brand new kitchenette with fridge/freezer and built-in microwave/convection combo. Apartment available furnished, but furniture can be removed for a reduced price...
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    Location Information
    Seneca, South Carolina
    Condo/Apartment - 1 Bedroom, 1 Bathroom, Sleeps 2
    LAKEFRONT! Dock available. 4 Bedroom 4 Bath Condo 1.5 Miles from Clemson Stadium1 / 20
    (36)Excellent
    4.8 miles from Lake Keowee Marina
    4 Bedrooms, 4 Bathrooms, Sleeps 10 Quick View
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    • Shared Outdoor Pool (Unheated)
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    Location Information
    Seneca, South Carolina
    Condo/Apartment - 4 Bedrooms, 4 Bathrooms, Sleeps 10
    Deepwater Cove on Beautiful Lake Keowee Complete with Dock and Kayaks1 / 49
    (56)Excellent
    4.5 miles from Lake Keowee Marina
    4 Bedrooms, 3 Bathrooms, Sleeps 14 Quick View
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    Location Information
    Seneca, South Carolina
    Rental Home - 4 Bedrooms, 3 Bathrooms, Sleeps 14
    20 Minutes to Clemson - Remodeled 4 BR/3 BA Waterfront1 / 27
    (71)Excellent
    4.2 miles from Lake Keowee Marina
    4 Bedrooms, 3 Bathrooms, Sleeps 10 Quick View
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    • Patio
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    Location Information
    Seneca, South Carolina
    Rental Home - 4 Bedrooms, 3 Bathrooms, Sleeps 10
    3/2 close to Clemson Oconee Nuclear Rivers Hiking1 / 25
    (11)Excellent
    1.0 miles from Lake Keowee Marina
    3 Bedrooms, 2 Bathrooms, Sleeps 6 Quick View
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    Location Information
    Seneca, South Carolina
    Rental Home - 3 Bedrooms, 2 Bathrooms, Sleeps 6
    Beautiful Log Cabin on Lake Keowee with Dock - Close to Clemson!1 / 47
    (33)Excellent
    4.6 miles from Lake Keowee Marina
    4 Bedrooms, 3 Bathrooms, Sleeps 10 Quick View
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    Location Information
    Seneca, South Carolina
    Rental Home - 4 Bedrooms, 3 Bathrooms, Sleeps 10
    Perfect getaway on emerald Lake Keowee, the cleanest lake in the Southeast.1 / 27
    (7)Excellent
    1.8 miles from Lake Keowee Marina
    4 Bedrooms, 3 Bathrooms, Sleeps 12 Quick View
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    Location Information
    Seneca, South Carolina
    Rental Home - 4 Bedrooms, 3 Bathrooms, Sleeps 12
    Beautiful Lake Keowee - Super clean home1 / 41
    (75)Excellent
    1.7 miles from Lake Keowee Marina
    5 Bedrooms, 4 Bathrooms, Sleeps 18 Quick View
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    Location Information
    Seneca, South Carolina
    Rental Home - 5 Bedrooms, 4 Bathrooms, Sleeps 18
    8.4 miles from Lake Keowee Marina
    4 Bedrooms, 2 Bathrooms, Sleeps 10 Quick View
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    Location Information
    Seneca, South Carolina
    Rental Home - 4 Bedrooms, 2 Bathrooms, Sleeps 10
    THE Premier Clemson /Seneca Lake Home1 / 45
    (22)Excellent
    6.3 miles from Lake Keowee Marina
    4 Bedrooms, 3 Bathrooms, Sleeps 10 Quick View
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    • Internet Access
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    Location Information
    Seneca, South Carolina
    Rental Home - 4 Bedrooms, 3 Bathrooms, Sleeps 10
    Fishing Cabin - Keowee 2 bedrooms, 2 bathrooms - Fishing - Kayaking - Porch1 / 21
    (34)Excellent
    5.1 miles from Lake Keowee Marina
    2 Bedrooms, 2 Bathrooms, Sleeps 4 Quick View
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    Location Information
    Seneca, South Carolina
    Rental Home - 2 Bedrooms, 2 Bathrooms, Sleeps 4
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