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Vacation Rentals near Main Street Hyannis

Main Street, Hyannis, Massachusetts 02601
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    Travelers to Hyannis are booking July dates now. Secure your vacation rental today, and have the perfect trip.
    All 148 Rentals in Hyannis
    0.7 miles from Main Street Hyannis
    3 Bedrooms, 2 Bathrooms, Sleeps 6 Quick View
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    0.6 miles from Main Street Hyannis
    2 Bedrooms, 2 Bathrooms, Sleeps 4 Quick View
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    Private, Spacious, and Water Front Home on Cape Cod1 / 30
    (30)Excellent
    2.3 miles from Main Street Hyannis
    6 Bedrooms, 4 Bathrooms, Sleeps 17 Quick View
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    Seaside Cape Cod Escape-Norris Cottages Bungalow: 3 Minutes to the Beach1 / 29
    (56)Excellent
    0.9 miles from Main Street Hyannis
    2 Bedrooms, 1 Bathroom, Sleeps 6 Quick View
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    Hyannis, Cape Cod
    Rental Home - 2 Bedrooms, 1 Bathroom, Sleeps 6
    Private Beach on Nantucket Sound - Walk to Beach, Town, Harbor. Newly updated.1 / 30
    (107)Excellent
    1.0 miles from Main Street Hyannis
    3 Bedrooms, 3 Bathrooms, Sleeps 10 Quick View
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    Hyannis, Cape Cod
    Rental Home - 3 Bedrooms, 3 Bathrooms, Sleeps 10
    Charming Hyannis Home ~ 1 Mi to Beach Access!1 / 30
    (3)Excellent
    1.3 miles from Main Street Hyannis
    3 Bedrooms, 2 Bathrooms, Sleeps 6 Quick View
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    Hyannis, Cape Cod
    Rental Home - 3 Bedrooms, 2 Bathrooms, Sleeps 6
    Cozy 'Sea Street Cottage' - 1 Mile to Ferry Boats!1 / 24
    (7)Very good
    0.3 miles from Main Street Hyannis
    2 Bedrooms, 1 Bathroom, Sleeps 5 Quick View
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    Hyannis, Cape Cod
    Rental Home - 2 Bedrooms, 1 Bathroom, Sleeps 5
    0.4 miles from Main Street Hyannis
    5 Bedrooms, 4 Bathrooms, Sleeps 10 Quick View
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    Hyannis, Cape Cod
    Rental Home - 5 Bedrooms, 4 Bathrooms, Sleeps 10
    Luxury Home steps to quiet Keyes Beach; Less than 1Mi to Main St; Awww the Deck!1 / 30
    (5)Excellent
    0.9 miles from Main Street Hyannis
    4 Bedrooms, 3 Bathrooms, Sleeps 9 Quick View
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    Hyannis, Cape Cod
    Rental Home - 4 Bedrooms, 3 Bathrooms, Sleeps 9
    0.3 miles from Main Street Hyannis
    3 Bedrooms, 1 Bathroom, Sleeps 7 Quick View
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    Hyannis, Cape Cod
    Rental Home - 3 Bedrooms, 1 Bathroom, Sleeps 7
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    0.2 miles from Main Street Hyannis
    2 Bedrooms, 2 Bathrooms, Sleeps 5 Quick View
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    Hyannis, Cape Cod
    Rental Home - 2 Bedrooms, 2 Bathrooms, Sleeps 5
    0.0 miles from Main Street Hyannis
    1 Bedroom, 1 Bathroom, Sleeps 4 Quick View
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    Hyannis, Cape Cod
    Condo/Apartment - 1 Bedroom, 1 Bathroom, Sleeps 4
    0.2 miles from Main Street Hyannis
    5 Bedrooms, 3 Bathrooms, Sleeps 12 Quick View
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    Hyannis, Cape Cod
    Rental Home - 5 Bedrooms, 3 Bathrooms, Sleeps 12
    0.4 miles from Main Street Hyannis
    3 Bedrooms, 2 Bathrooms, Sleeps 6 Quick View
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    Hyannis, Cape Cod
    Rental Home - 3 Bedrooms, 2 Bathrooms, Sleeps 6
    0.7 miles from Main Street Hyannis
    Studio, 1 Bathroom, Sleeps 2 Quick View
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    Hyannis, Cape Cod
    Condo/Apartment - 1 Bathroom, Sleeps 2
    1.7 miles from Main Street Hyannis
    3 Bedrooms, 3 Bathrooms, Sleeps 8 Quick View
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    Hyannis, Cape Cod
    Rental Home - 3 Bedrooms, 3 Bathrooms, Sleeps 8
    0.8 miles from Main Street Hyannis
    3 Bedrooms, 2 Bathrooms, Sleeps 7 Quick View
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    Hyannis, Cape Cod
    Rental Home - 3 Bedrooms, 2 Bathrooms, Sleeps 7
    1.0 miles from Main Street Hyannis
    6 Bedrooms, 6 Bathrooms, Sleeps 15 Quick View
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    Hyannis, Cape Cod
    Rental Home - 6 Bedrooms, 6 Bathrooms, Sleeps 15
    0.9 miles from Main Street Hyannis
    4 Bedrooms, 3 Bathrooms, Sleeps 10 Quick View
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    Hyannis, Cape Cod
    Rental Home - 4 Bedrooms, 3 Bathrooms, Sleeps 10
    0.9 miles from Main Street Hyannis
    4 Bedrooms, 4 Bathrooms, Sleeps 10 Quick View
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    Hyannis, Cape Cod
    Rental Home - 4 Bedrooms, 4 Bathrooms, Sleeps 10
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    0.7 miles from Main Street Hyannis
    3 Bedrooms, 2 Bathrooms, Sleeps 8 Quick View
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    Hyannis, Cape Cod
    Rental Home - 3 Bedrooms, 2 Bathrooms, Sleeps 8
    0.1 miles from Main Street Hyannis
    3 Bedrooms, 2 Bathrooms, Sleeps 10 Quick View
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    Hyannis, Cape Cod
    Rental Home - 3 Bedrooms, 2 Bathrooms, Sleeps 10
    0.5 miles from Main Street Hyannis
    3 Bedrooms, 1 Bathroom, Sleeps 6 Quick View
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    Hyannis, Cape Cod
    Rental Home - 3 Bedrooms, 1 Bathroom, Sleeps 6
    1.0 miles from Main Street Hyannis
    4 Bedrooms, 3 Bathrooms, Sleeps 6 Quick View
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    Hyannis, Cape Cod
    Rental Home - 4 Bedrooms, 3 Bathrooms, Sleeps 6
    Beautiful House in Hyannis Harbor! Perfect Location & Beach Pass! JUNE SPECIALS!1 / 30
    (6)Excellent
    0.5 miles from Main Street Hyannis
    4 Bedrooms, 2 Bathrooms, Sleeps 10 Quick View
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    Hyannis, Cape Cod
    Rental Home - 4 Bedrooms, 2 Bathrooms, Sleeps 10
    Cute, Clean & Conveniently Located & Pets Welcomed1 / 22
    (60)Excellent
    1.5 miles from Main Street Hyannis
    3 Bedrooms, 1 Bathroom, Sleeps 6 Quick View
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    Hyannis, Cape Cod
    Rental Home - 3 Bedrooms, 1 Bathroom, Sleeps 6
    Walk To Beaches, Main Street, and Harbor. 1BR Cottage. Quiet Area. Captain1 / 30
    (3)Excellent
    0.7 miles from Main Street Hyannis
    1 Bedroom, 1 Bathroom, Sleeps 3 Quick View
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    Hyannis, Cape Cod
    Condo/Apartment - 1 Bedroom, 1 Bathroom, Sleeps 3
    Walk To Beaches, Main Street, and Harbor. Quiet Neighborhood. Captain Gosnold1 / 25
    (9)Excellent
    0.7 miles from Main Street Hyannis
    Studio, 1 Bathroom, Sleeps 2 Quick View
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    Hyannis, Cape Cod
    Condo/Apartment - 1 Bathroom, Sleeps 2
    0.4 miles from Main Street Hyannis
    2 Bedrooms, 1 Bathroom, Sleeps 6 Quick View
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    Hyannis, Cape Cod
    Rental Home - 2 Bedrooms, 1 Bathroom, Sleeps 6
    Beautiful and spacious home close to Keys Memorial Beach and Main Street fun!1 / 30
    (6)Excellent
    0.8 miles from Main Street Hyannis
    4 Bedrooms, 3 Bathrooms, Sleeps 8 Quick View
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    Hyannis, Cape Cod
    Rental Home - 4 Bedrooms, 3 Bathrooms, Sleeps 8
    1.7 miles from Main Street Hyannis
    5 Bedrooms, 4 Bathrooms, Sleeps 12 Quick View
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    Hyannis, Cape Cod
    Rental Home - 5 Bedrooms, 4 Bathrooms, Sleeps 12
    One of Kind Open-Air Near Everything AC and WiFi1 / 30
    (20)Very good
    1.3 miles from Main Street Hyannis
    3 Bedrooms, 3 Bathrooms, Sleeps 6 Quick View
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    Hyannis, Cape Cod
    Rental Home - 3 Bedrooms, 3 Bathrooms, Sleeps 6
    0.6 miles from Main Street Hyannis
    2 Bedrooms, 1 Bathroom, Sleeps 5 Quick View
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    Hyannis, Cape Cod
    Rental Home - 2 Bedrooms, 1 Bathroom, Sleeps 5
    1.2 miles from Main Street Hyannis
    4 Bedrooms, 3 Bathrooms, Sleeps 7 Quick View
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    Hyannis, Cape Cod
    Rental Home - 4 Bedrooms, 3 Bathrooms, Sleeps 7
    Luxe Waterfront Getaway - 1 Mile to Ferry & Beach!1 / 28
    (2)Excellent
    0.6 miles from Main Street Hyannis
    4 Bedrooms, 3 Bathrooms, Sleeps 10 Quick View
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    Hyannis, Cape Cod
    Rental Home - 4 Bedrooms, 3 Bathrooms, Sleeps 10
    43 by the Sea1 / 30
    (4)Excellent
    0.9 miles from Main Street Hyannis
    3 Bedrooms, 3 Bathrooms, Sleeps 6 Quick View
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    Hyannis, Cape Cod
    Rental Home - 3 Bedrooms, 3 Bathrooms, Sleeps 6
    0.9 miles from Main Street Hyannis
    3 Bedrooms, 4 Bathrooms, Sleeps 8 Quick View
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    Hyannis, Cape Cod
    Rental Home - 3 Bedrooms, 4 Bathrooms, Sleeps 8
    0.9 miles from Main Street Hyannis
    1 Bedroom, 1 Bathroom, Sleeps 4 Quick View
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    Hyannis, Cape Cod
    Condo/Apartment - 1 Bedroom, 1 Bathroom, Sleeps 4
    0.6 miles from Main Street Hyannis
    5 Bedrooms, 3 Bathrooms, Sleeps 10 Quick View
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    Hyannis, Cape Cod
    Rental Home - 5 Bedrooms, 3 Bathrooms, Sleeps 10
    1.9 miles from Main Street Hyannis
    3 Bedrooms, 3 Bathrooms, Sleeps 10 Quick View
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    Hyannis, Cape Cod
    Condo/Apartment - 3 Bedrooms, 3 Bathrooms, Sleeps 10
    ✸Private Sandy Beach✸ Nantucket Sound, Walk to Beach, Harbor, Town. Kayak & SUP1 / 30
    (16)Excellent
    0.9 miles from Main Street Hyannis
    3 Bedrooms, 3 Bathrooms, Sleeps 7 Quick View
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    Hyannis, Cape Cod
    Rental Home - 3 Bedrooms, 3 Bathrooms, Sleeps 7
    0.4 miles from Main Street Hyannis
    3 Bedrooms, 2 Bathrooms, Sleeps 5 Quick View
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    Hyannis, Cape Cod
    Rental Home - 3 Bedrooms, 2 Bathrooms, Sleeps 5
    0.8 miles from Main Street Hyannis
    3 Bedrooms, 4 Bathrooms, Sleeps 6 Quick View
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    Hyannis, Cape Cod
    Rental Home - 3 Bedrooms, 4 Bathrooms, Sleeps 6
    0.7 miles from Main Street Hyannis
    3 Bedrooms, 3 Bathrooms, Sleeps 8 Quick View
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    Hyannis, Cape Cod
    Condo/Apartment - 3 Bedrooms, 3 Bathrooms, Sleeps 8
    0.6 miles from Main Street Hyannis
    6 Bedrooms, 4 Bathrooms, Sleeps 14 Quick View
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    Hyannis, Cape Cod
    Rental Home - 6 Bedrooms, 4 Bathrooms, Sleeps 14
    0.8 miles from Main Street Hyannis
    5 Bedrooms, 4 Bathrooms, Sleeps 10 Quick View
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    Hyannis, Cape Cod
    Rental Home - 5 Bedrooms, 4 Bathrooms, Sleeps 10
    Good time to book! 2 weeks available july & Aug1 / 30
    (3)Excellent
    1.8 miles from Main Street Hyannis
    3 Bedrooms, 3 Bathrooms, Sleeps 9 Quick View
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    Hyannis, Cape Cod
    Rental Home - 3 Bedrooms, 3 Bathrooms, Sleeps 9
    0.7 miles from Main Street Hyannis
    6 Bedrooms, 3 Bathrooms, Sleeps 18 Quick View
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    • Grill
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    Smoking allowed
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    Hyannis, Cape Cod
    Rental Home - 6 Bedrooms, 3 Bathrooms, Sleeps 18
    Barefoot Walk to Beaches   • AC • Free WiFi • Pet Friendly. Sept 2023 Available1 / 30
    (4)Excellent
    0.8 miles from Main Street Hyannis
    4 Bedrooms, 5 Bathrooms, Sleeps 12 Quick View
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    • Hot Tub
    • Washer
    • Balcony
    • Grill
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    Smoking allowed
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    Location Information
    Hyannis, Cape Cod
    Rental Home - 4 Bedrooms, 5 Bathrooms, Sleeps 12
    0.9 miles from Main Street Hyannis
    3 Bedrooms, 3 Bathrooms, Sleeps 8 Quick View
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    • Washer
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    • Patio
    • Air Conditioning
    • DVD Player
    Suitability
    Pet friendly
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    Smoking allowed
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    Location Information
    Hyannis, Cape Cod
    Rental Home - 3 Bedrooms, 3 Bathrooms, Sleeps 8
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