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Vacation Rentals near National Key Deer Refuge

30587 Overseas Hwy, Big Pine Key, Florida 33043-3400
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    Travelers to Big Pine Key are booking January dates now. Secure your vacation rental today, and have the perfect trip.
    All 151 Rentals in Big Pine Key
    Lower Keys Retreat.....1 / 32
    (1)Excellent
    1.8 miles from National Key Deer Refuge
    3 Bedrooms, 3 Bathrooms, Sleeps 8 Quick View
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    Island Time 2 (half of duplex)1 / 17
    1.8 miles from National Key Deer Refuge
    3 Bedrooms, 1 Bathroom, Sleeps 6 Quick View
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    Island Time (both halves of duplex)1 / 27
    0.3 miles from National Key Deer Refuge
    5 Bedrooms, 2 Bathrooms, Sleeps 10 Quick View
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    Waterfront Big Pine Key Paradise1 / 25
    (25)Excellent
    2.1 miles from National Key Deer Refuge
    2 Bedrooms, 2 Bathrooms, Sleeps 6 Quick View
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    Big Pine Key, Florida Keys
    Rental Home - 2 Bedrooms, 2 Bathrooms, Sleeps 6
    BIg Pine Key New House 75 ft dock 250 feet from open waters of Pine Channel1 / 30
    (12)Excellent
    1.0 miles from National Key Deer Refuge
    3 Bedrooms, 2 Bathrooms, Sleeps 8 Quick View
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    Big Pine Key, Florida Keys
    Rental Home - 3 Bedrooms, 2 Bathrooms, Sleeps 8
    Mickey and Lynn's House of Windows1 / 15
    (8)Excellent
    0.6 miles from National Key Deer Refuge
    3 Bedrooms, 3 Bathrooms, Sleeps 8 Quick View
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    Big Pine Key, Florida Keys
    Rental Home - 3 Bedrooms, 3 Bathrooms, Sleeps 8
    2/2 Canal Front Home Big Pine Key. Easy ocean and gulf access!1 / 17
    (12)Excellent
    2.1 miles from National Key Deer Refuge
    2 Bedrooms, 2 Bathrooms, Sleeps 6 Quick View
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    Big Pine Key, Florida Keys
    Rental Home - 2 Bedrooms, 2 Bathrooms, Sleeps 6
    SPCL FALL RATES __THREE LOTS WITH POOL AND DOCK!! SECLUDED LOWER KEYS RETREAT1 / 28
    (9)Excellent
    2.3 miles from National Key Deer Refuge
    2 Bedrooms, 2 Bathrooms, Sleeps 6 Quick View
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    Big Pine Key, Florida Keys
    Rental Home - 2 Bedrooms, 2 Bathrooms, Sleeps 6
    Tropical Caribbean Wonderland1 / 19
    (45)Very good
    0.7 miles from National Key Deer Refuge
    1 Bedroom, 1 Bathroom, Sleeps 4 Quick View
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    Big Pine Key, Florida Keys
    Rental Home - 1 Bedroom, 1 Bathroom, Sleeps 4
    Canal Front Paradise!1 / 20
    (5)Excellent
    1.6 miles from National Key Deer Refuge
    2 Bedrooms, 2 Bathrooms, Sleeps 8 Quick View
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    Big Pine Key, Florida Keys
    Rental Home - 2 Bedrooms, 2 Bathrooms, Sleeps 8
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    Big Pine Key Waterfront Home: Boating, Sunrises, Sunsets; Relax in Paradise!1 / 30
    0.8 miles from National Key Deer Refuge
    3 Bedrooms, 2 Bathrooms, Sleeps 6 Quick View
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    Big Pine Key, Florida Keys
    Rental Home - 3 Bedrooms, 2 Bathrooms, Sleeps 6
    Yellowstone by the Sea1 / 17
    4.2 miles from National Key Deer Refuge
    2 Bedrooms, 2 Bathrooms, Sleeps 6 Quick View
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    Big Pine Key, Florida Keys
    Rental Home - 2 Bedrooms, 2 Bathrooms, Sleeps 6
    Welcome to Casa Del Mar ***********1 / 30
    1.7 miles from National Key Deer Refuge
    3 Bedrooms, 2 Bathrooms, Sleeps 12 Quick View
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    Big Pine Key, Florida Keys
    Rental Home - 3 Bedrooms, 2 Bathrooms, Sleeps 12
    Waterfront vacation home in Big Pine Key1 / 30
    1.4 miles from National Key Deer Refuge
    4 Bedrooms, 3 Bathrooms, Sleeps 1 Quick View
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    Big Pine Key, Florida Keys
    Rental Home - 4 Bedrooms, 3 Bathrooms, Sleeps 1
    Big Pine Latitude Adjustment1 / 30
    0.8 miles from National Key Deer Refuge
    5 Bedrooms, 3 Bathrooms, Sleeps 10 Quick View
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    Big Pine Key, Florida Keys
    Rental Home - 5 Bedrooms, 3 Bathrooms, Sleeps 10
    Star Room Barnacle Bed and Breakfast1 / 7
    2.3 miles from National Key Deer Refuge
    1 Bedroom, 1 Bathroom, Sleeps 2 Quick View
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    Big Pine Key, Florida Keys
    Rental Home - 1 Bedroom, 1 Bathroom, Sleeps 2
    Reel Paradise on Big Pine Key1 / 30
    2.1 miles from National Key Deer Refuge
    2 Bedrooms, 2 Bathrooms, Sleeps 6 Quick View
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    Big Pine Key, Florida Keys
    Rental Home - 2 Bedrooms, 2 Bathrooms, Sleeps 6
    Waterfront home with screened lanai, patio, central AC, & washer/dryer1 / 30
    1.0 miles from National Key Deer Refuge
    3 Bedrooms, 2 Bathrooms, Sleeps 6 Quick View
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    Big Pine Key, Florida Keys
    Rental Home - 3 Bedrooms, 2 Bathrooms, Sleeps 6
    Doctors Arm waterfront with pool and Tiki hut. AVAILABLE Jan 1- 28, 2024.1 / 30
    2.2 miles from National Key Deer Refuge
    3 Bedrooms, 2 Bathrooms, Sleeps 8 Quick View
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    Big Pine Key, Florida Keys
    Rental Home - 3 Bedrooms, 2 Bathrooms, Sleeps 8
    Excellent boating location-65 ft frontage on deep canal1 / 30
    0.8 miles from National Key Deer Refuge
    2 Bedrooms, 2 Bathrooms, Sleeps 6 Quick View
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    Big Pine Key, Florida Keys
    Rental Home - 2 Bedrooms, 2 Bathrooms, Sleeps 6
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    PADGETT PARADISE with Two Boat Slips with Filet Table. POOL1 / 23
    4.1 miles from National Key Deer Refuge
    3 Bedrooms, 4 Bathrooms, Sleeps 8 Quick View
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    Big Pine Key, Florida Keys
    Rental Home - 3 Bedrooms, 4 Bathrooms, Sleeps 8
    Heavenly Hideout, 2 Bedroom Canal Home in Eden Pines1 / 30
    2.0 miles from National Key Deer Refuge
    2 Bedrooms, 2 Bathrooms, Sleeps 6 Quick View
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    Big Pine Key, Florida Keys
    Rental Home - 2 Bedrooms, 2 Bathrooms, Sleeps 6
    Beautiful Family Big Pine Retreat! Short drive to Key West!1 / 18
    1.9 miles from National Key Deer Refuge
    3 Bedrooms, 2 Bathrooms, Sleeps 8 Quick View
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    Big Pine Key, Florida Keys
    Rental Home - 3 Bedrooms, 2 Bathrooms, Sleeps 8
    Big Pine Bungalow: Serene Backyard Oasis, Pool/Spa, Expansive Canal-Facing Deck1 / 50
    0.6 miles from National Key Deer Refuge
    3 Bedrooms, 2 Bathrooms, Sleeps 7 Quick View
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    • Private Outdoor Pool (Unheated)
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    About this property
    Welcome to Big Pine Bungalow, a beautifully updated waterfront home where you can immerse yourself in the quintessential Florida Keys lifestyle. Situated on a plugged canal, offering no boating access, this haven provides plenty of opportunities for fishing, kayaking, paddle boarding, and...
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    Big Pine Key, Florida Keys
    Rental Home - 3 Bedrooms, 2 Bathrooms, Sleeps 7
    Newly Remodeled Corner House on the Water1 / 10
    4.3 miles from National Key Deer Refuge
    2 Bedrooms, 2 Bathrooms, Sleeps 6 Quick View
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    Big Pine Key, Florida Keys
    Rental Home - 2 Bedrooms, 2 Bathrooms, Sleeps 6
    LARGE LOT & RV | LOWER KEYS1 / 30
    0.6 miles from National Key Deer Refuge
    1 Bedroom, 1 Bathroom, Sleeps 4 Quick View
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    Big Pine Key, Florida Keys
    Rental Home - 1 Bedroom, 1 Bathroom, Sleeps 4
    3 BEDROOM BEACH HOUSE CLOSE TO BEACH & KEY WEST1 / 30
    0.6 miles from National Key Deer Refuge
    3 Bedrooms, 2 Bathrooms, Sleeps 12 Quick View
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    Big Pine Key, Florida Keys
    Rental Home - 3 Bedrooms, 2 Bathrooms, Sleeps 12
    Ground Level Canal front 3 bedroom 2 full bathrooms-Pool Fixed bridge1 / 30
    1.6 miles from National Key Deer Refuge
    3 Bedrooms, 2 Bathrooms, Sleeps 8 Quick View
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    Big Pine Key, Florida Keys
    Rental Home - 3 Bedrooms, 2 Bathrooms, Sleeps 8
    Modern multi story waterfront home, 30 minutes from Key west.1 / 27
    1.0 miles from National Key Deer Refuge
    4 Bedrooms, 3 Bathrooms, Sleeps 12 Quick View
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    Big Pine Key, Florida Keys
    Rental Home - 4 Bedrooms, 3 Bathrooms, Sleeps 12
    FISHERMANS DREAM HOUSE1 / 16
    2.0 miles from National Key Deer Refuge
    3 Bedrooms, 2 Bathrooms, Sleeps 8 Quick View
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    Big Pine Key, Florida Keys
    Rental Home - 3 Bedrooms, 2 Bathrooms, Sleeps 8
    Lower Keys Retreat.....1 / 30
    (5)Very good
    1.8 miles from National Key Deer Refuge
    3 Bedrooms, 3 Bathrooms, Sleeps 8 Quick View
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    Big Pine Key, Florida Keys
    Rental Home - 3 Bedrooms, 3 Bathrooms, Sleeps 8
    Canal Front Home Showcasing Stellar Sunsets with Ocean Access1 / 7
    2.0 miles from National Key Deer Refuge
    3 Bedrooms, 3 Bathrooms, Sleeps 10 Quick View
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    Big Pine Key, Florida Keys
    Rental Home - 3 Bedrooms, 3 Bathrooms, Sleeps 10
    Luxury and Lovely Water Front House1 / 30
    1.0 miles from National Key Deer Refuge
    2 Bedrooms, 2 Bathrooms, Sleeps 4 Quick View
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    Big Pine Key, Florida Keys
    Rental Home - 2 Bedrooms, 2 Bathrooms, Sleeps 4
    New listing 3bd/2bt Sleeps 8 "Sunset Paradise Villa" on canal Big Pine Key1 / 30
    1.6 miles from National Key Deer Refuge
    3 Bedrooms, 2 Bathrooms, Sleeps 8 Quick View
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    Big Pine Key, Florida Keys
    Rental Home - 3 Bedrooms, 2 Bathrooms, Sleeps 8
    Lovely Canal Front Big Pine Key House1 / 12
    2.4 miles from National Key Deer Refuge
    3 Bedrooms, 2 Bathrooms, Sleeps 6 Quick View
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    Big Pine Key, Florida Keys
    Rental Home - 3 Bedrooms, 2 Bathrooms, Sleeps 6
    You’re on island time at “The Island Girl”.1 / 12
    0.8 miles from National Key Deer Refuge
    2 Bedrooms, 1 Bathroom, Sleeps 4 Quick View
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    Big Pine Key, Florida Keys
    Rental Home - 2 Bedrooms, 1 Bathroom, Sleeps 4
    New Big pine home resort1 / 13
    2.6 miles from National Key Deer Refuge
    3 Bedrooms, 3 Bathrooms, Sleeps 10 Quick View
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    Big Pine Key, Florida Keys
    Rental Home - 3 Bedrooms, 3 Bathrooms, Sleeps 10
    Paradise Found ! Fully updated Waterfront Home- GREAT FISHING1 / 12
    2.2 miles from National Key Deer Refuge
    2 Bedrooms, 2 Bathrooms, Sleeps 4 Quick View
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    Big Pine Key, Florida Keys
    Rental Home - 2 Bedrooms, 2 Bathrooms, Sleeps 4
    Sharkys Island Paradise1 / 47
    (1)Excellent
    1.0 miles from National Key Deer Refuge
    5 Bedrooms, 3 Bathrooms, Sleeps 12 Quick View
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    • Ocean Views
    • Washer
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    Beautiful Spacious Home
    Reviewed 4 weeks ago
    Geogeous home with lots of room for a big family! Five bedrooms with lots of space and located on Pine Channels with access to the Gulf & Atlantic
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    About this property
    This spacious waterfront 5-bedroom home is a one of a kind and was built by owner native to the Keys. The home is unique with very vibrant colors and a Keysie atmosphere. Pine Channel Estates is a very private, quiet & safe neighborhood with the top canals in the lower Keys. You will love just...
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    Big Pine Key, Florida Keys
    Rental Home - 5 Bedrooms, 3 Bathrooms, Sleeps 12
    Coral Palms -Secluded tropical oasis pool and dock1 / 30
    4.6 miles from National Key Deer Refuge
    3 Bedrooms, 2 Bathrooms, Sleeps 7 Quick View
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    Big Pine Key, Florida Keys
    Rental Home - 3 Bedrooms, 2 Bathrooms, Sleeps 7
    You can see the ocean from every room in this house… look no further. ☀️1 / 30
    2.1 miles from National Key Deer Refuge
    3 Bedrooms, 2 Bathrooms, Sleeps 6 Quick View
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    Big Pine Key, Florida Keys
    Rental Home - 3 Bedrooms, 2 Bathrooms, Sleeps 6
    2 Bedroom/2 Bath Canal Home in Big Pine - Great Boating Access!1 / 15
    4.5 miles from National Key Deer Refuge
    2 Bedrooms, 2 Bathrooms, Sleeps 6 Quick View
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    Big Pine Key, Florida Keys
    Rental Home - 2 Bedrooms, 2 Bathrooms, Sleeps 6
    Dates available Oct, Nov, Dec 20231 / 30
    2.3 miles from National Key Deer Refuge
    2 Bedrooms, 2 Bathrooms, Sleeps 7 Quick View
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    Big Pine Key, Florida Keys
    Rental Home - 2 Bedrooms, 2 Bathrooms, Sleeps 7
    Awesome Open Water View at Blue Heron Estate1 / 24
    (23)Excellent
    1.2 miles from National Key Deer Refuge
    4 Bedrooms, 5 Bathrooms, Sleeps 9 Quick View
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    Big Pine Key, Florida Keys
    Rental Home - 4 Bedrooms, 5 Bathrooms, Sleeps 9
    Treehouse1 / 21
    2.4 miles from National Key Deer Refuge
    1 Bedroom, 1 Bathroom, Sleeps 2 Quick View
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    Big Pine Key, Florida Keys
    Rental Home - 1 Bedroom, 1 Bathroom, Sleeps 2
    Canal Front Home With Pool And Hot Tub1 / 30
    2.2 miles from National Key Deer Refuge
    2 Bedrooms, 3 Bathrooms, Sleeps 6 Quick View
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    Big Pine Key, Florida Keys
    Rental Home - 2 Bedrooms, 3 Bathrooms, Sleeps 6
    Casa Blanca - Gorgeous ground-level boating home1 / 30
    1.5 miles from National Key Deer Refuge
    3 Bedrooms, 2 Bathrooms, Sleeps 6 Quick View
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    Big Pine Key, Florida Keys
    Rental Home - 3 Bedrooms, 2 Bathrooms, Sleeps 6
    NEW TO MARKET1 / 22
    1.0 miles from National Key Deer Refuge
    3 Bedrooms, 2 Bathrooms, Sleeps 10 Quick View
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    Big Pine Key, Florida Keys
    Rental Home - 3 Bedrooms, 2 Bathrooms, Sleeps 10
    Canal front home in Big Pine Key1 / 30
    4.3 miles from National Key Deer Refuge
    3 Bedrooms, 2 Bathrooms, Sleeps 8 Quick View
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    Big Pine Key, Florida Keys
    Rental Home - 3 Bedrooms, 2 Bathrooms, Sleeps 8
    Secluded Hideaway- pivate pool and boat dockage1 / 30
    4.6 miles from National Key Deer Refuge
    3 Bedrooms, 2 Bathrooms, Sleeps 6 Quick View
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    Big Pine Key, Florida Keys
    Rental Home - 3 Bedrooms, 2 Bathrooms, Sleeps 6
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