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Wytheville Vacation Rentals

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44 rentals in Wytheville.
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Charming, secluded turn of the century home ideal for a relaxing family retreat, vacation rental in Wytheville
Charming, secluded turn of the century home ideal for a relaxing family retreat, vacation rental in Wytheville
Charming, secluded turn of the century home ideal for a relaxing family retreat, vacation rental in Wytheville

Charming, secluded turn of the century home ideal for a relaxing family retreat

Rental Home
5 bedrooms
4 bathrooms
Sleeps 10
Match: Sleeps
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NEW! Nature Escape in Wytheville w/ Covered Porch!, vacation rental in Wytheville
NEW! Nature Escape in Wytheville w/ Covered Porch!, vacation rental in Wytheville
NEW! Nature Escape in Wytheville w/ Covered Porch!, vacation rental in Wytheville

NEW! Nature Escape in Wytheville w/ Covered Porch!

Rental Home
2 bedrooms
1 bathroom
Sleeps 5
Match: Sleeps
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A Romantic Riverside Cabin. We are pet friendly., vacation rental in Wytheville
A Romantic Riverside Cabin. We are pet friendly., vacation rental in Wytheville
A Romantic Riverside Cabin. We are pet friendly., vacation rental in Wytheville

A Romantic Riverside Cabin. We are pet friendly.

Rental Home
1 bedroom
1 bathroom
Sleeps 4
Match: Sleeps
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Bear's Lair Cabin on the New River~ Relax in Rustic Elegance~210/night inSummer, vacation rental in Wytheville
Bear's Lair Cabin on the New River~ Relax in Rustic Elegance~210/night inSummer, vacation rental in Wytheville
Bear's Lair Cabin on the New River~ Relax in Rustic Elegance~210/night inSummer, vacation rental in Wytheville

Bear's Lair Cabin on the New River~ Relax in Rustic Elegance~210/night inSummer

Rental Home
3 bedrooms
2 bathrooms
Sleeps 7
Match: Sleeps
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Cozy River Front Apartment, vacation rental in Wytheville
Cozy River Front Apartment, vacation rental in Wytheville
Cozy River Front Apartment, vacation rental in Wytheville

Cozy River Front Apartment

Condo/Apartment
2 bedrooms
1 bathroom
Sleeps 5
Match: Sleeps
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Get away from all the Drama and Escape to Virginia's Blue Ridge!, vacation rental in Wytheville
Get away from all the Drama and Escape to Virginia's Blue Ridge!, vacation rental in Wytheville
Get away from all the Drama and Escape to Virginia's Blue Ridge!, vacation rental in Wytheville

Get away from all the Drama and Escape to Virginia's Blue Ridge!

Rental Home
1 bedroom
2 bathrooms
Sleeps 2
Match: Sleeps
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Luxury Cabin for 20, Million Dollar View Lake Estate, Book Now for Summer & Fall

Rental Home
5 bedrooms
4 bathrooms
Sleeps 20
Match: Sleeps
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Guest House In Burkes Garden VA At The Appalachian Trail And On Va Bike Trail, vacation rental in Wytheville
Guest House In Burkes Garden VA At The Appalachian Trail And On Va Bike Trail, vacation rental in Wytheville
Guest House In Burkes Garden VA At The Appalachian Trail And On Va Bike Trail, vacation rental in Wytheville

Guest House In Burkes Garden VA At The Appalachian Trail And On Va Bike Trail

Rental Home
5 bedrooms
4 bathrooms
Sleeps 11
Match: Sleeps
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Secluded Log Cabin With Gorgeous Mountain View, vacation rental in Wytheville
Secluded Log Cabin With Gorgeous Mountain View, vacation rental in Wytheville
Secluded Log Cabin With Gorgeous Mountain View, vacation rental in Wytheville

Secluded Log Cabin With Gorgeous Mountain View

Rental Home
1 bedroom
1 bathroom
Sleeps 2
Match: Sleeps
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Waterfront Cabin On The New River - Near Virginia Tech & Radford University, vacation rental in Wytheville
Waterfront Cabin On The New River - Near Virginia Tech & Radford University, vacation rental in Wytheville
Waterfront Cabin On The New River - Near Virginia Tech & Radford University, vacation rental in Wytheville

Waterfront Cabin On The New River - Near Virginia Tech & Radford University

Rental Home
2 bedrooms
2 bathrooms
Sleeps 6
Match: Sleeps
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On 'The New River Trail', vacation rental in Wytheville
On 'The New River Trail', vacation rental in Wytheville
On 'The New River Trail', vacation rental in Wytheville

On 'The New River Trail'

Rental Home
3 bedrooms
2 bathrooms
Sleeps 8
Match: Sleeps
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PRIVATE 150FT WATERFALL RIGHT OFF DECK! Rustic, Asian inspired., vacation rental in Wytheville
PRIVATE 150FT WATERFALL RIGHT OFF DECK! Rustic, Asian inspired., vacation rental in Wytheville
PRIVATE 150FT WATERFALL RIGHT OFF DECK! Rustic, Asian inspired., vacation rental in Wytheville

PRIVATE 150FT WATERFALL RIGHT OFF DECK! Rustic, Asian inspired.

Rental Home
1 bedroom
2 bathrooms
Sleeps 2
Match: Sleeps
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Peace, quiet & relaxation!  Family friendly home., vacation rental in Wytheville
Peace, quiet & relaxation!  Family friendly home., vacation rental in Wytheville
Peace, quiet & relaxation!  Family friendly home., vacation rental in Wytheville

Peace, quiet & relaxation! Family friendly home.

Rental Home
4 bedrooms
2 bathrooms
Sleeps 8
Match: Sleeps
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Stay in a 200 Year Old Log Cabin with Modern Conveniences, vacation rental in Wytheville
Stay in a 200 Year Old Log Cabin with Modern Conveniences, vacation rental in Wytheville
Stay in a 200 Year Old Log Cabin with Modern Conveniences, vacation rental in Wytheville

Stay in a 200 Year Old Log Cabin with Modern Conveniences

Rental Home
1 bedroom
1 bathroom
Sleeps 3
Match: Sleeps
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Secluded rustic log cabin at 4,000 ft with spectacular views & modern amenities., vacation rental in Wytheville
Secluded rustic log cabin at 4,000 ft with spectacular views & modern amenities., vacation rental in Wytheville
Secluded rustic log cabin at 4,000 ft with spectacular views & modern amenities., vacation rental in Wytheville

Secluded rustic log cabin at 4,000 ft with spectacular views & modern amenities.

Rental Home
3 bedrooms
2 bathrooms
Sleeps 10
Match: Sleeps
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Outdoor Enthusiasts 3 Bdrm retreat Blue Ridge Mountains Jefferson National Frst, vacation rental in Wytheville
Outdoor Enthusiasts 3 Bdrm retreat Blue Ridge Mountains Jefferson National Frst, vacation rental in Wytheville
Outdoor Enthusiasts 3 Bdrm retreat Blue Ridge Mountains Jefferson National Frst, vacation rental in Wytheville

Outdoor Enthusiasts 3 Bdrm retreat Blue Ridge Mountains Jefferson National Frst

Rental Home
3 bedrooms
1 bathroom
Sleeps 6
Match: Sleeps
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Cabin in the Blue Ridge, 10% discount for Military and Christian Groups, vacation rental in Wytheville
Cabin in the Blue Ridge, 10% discount for Military and Christian Groups, vacation rental in Wytheville
Cabin in the Blue Ridge, 10% discount for Military and Christian Groups, vacation rental in Wytheville

Cabin in the Blue Ridge, 10% discount for Military and Christian Groups

Rental Home
9 bedrooms
4 bathrooms
Sleeps 30
Match: Sleeps
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Private, Secluded Small Mountain Top 2 Story Cabin With 7 Plus Acres, vacation rental in Wytheville
Private, Secluded Small Mountain Top 2 Story Cabin With 7 Plus Acres, vacation rental in Wytheville
Private, Secluded Small Mountain Top 2 Story Cabin With 7 Plus Acres, vacation rental in Wytheville

Private, Secluded Small Mountain Top 2 Story Cabin With 7 Plus Acres

Rental Home
2 bedrooms
3 bathrooms
Sleeps 6
Match: Sleeps
More info
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Cozy, Waterfront Home on New River - Onida, vacation rental in Wytheville
Cozy, Waterfront Home on New River - Onida, vacation rental in Wytheville
Cozy, Waterfront Home on New River - Onida, vacation rental in Wytheville

Cozy, Waterfront Home on New River - Onida

Rental Home
2 bedrooms
1 bathroom
Sleeps 2
Match: Sleeps
More info
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Quiet, Rustic, Getaway, Tranquil Retreat, vacation rental in Wytheville
Quiet, Rustic, Getaway, Tranquil Retreat, vacation rental in Wytheville
Quiet, Rustic, Getaway, Tranquil Retreat, vacation rental in Wytheville

Quiet, Rustic, Getaway, Tranquil Retreat

Rental Home
2 bedrooms
1 bathroom
Sleeps 4
Match: Sleeps
More info
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Log Cabin - Romantic River Front Getaway on the New River, vacation rental in Wytheville
Log Cabin - Romantic River Front Getaway on the New River, vacation rental in Wytheville
Log Cabin - Romantic River Front Getaway on the New River, vacation rental in Wytheville

Log Cabin - Romantic River Front Getaway on the New River

Rental Home
2 bedrooms
2 bathrooms
Sleeps 4
Match: Sleeps
More info
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Winter Get Away, vacation rental in Wytheville
Winter Get Away, vacation rental in Wytheville
Winter Get Away, vacation rental in Wytheville

Winter Get Away

Rental Home
2 bedrooms
1 bathroom
Sleeps 4
Match: Sleeps
More info
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Stay at the Rural Retreat Winery Suite and overlook the Historic Depot, vacation rental in Wytheville
Stay at the Rural Retreat Winery Suite and overlook the Historic Depot, vacation rental in Wytheville
Stay at the Rural Retreat Winery Suite and overlook the Historic Depot, vacation rental in Wytheville

Stay at the Rural Retreat Winery Suite and overlook the Historic Depot

Condo/Apartment
2 bedrooms
1 bathroom
Sleeps 6
Match: Sleeps
More info
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Fireflies Cabin on the New River, vacation rental in Wytheville
Fireflies Cabin on the New River, vacation rental in Wytheville
Fireflies Cabin on the New River, vacation rental in Wytheville

Fireflies Cabin on the New River

Rental Home
1 bedroom
1 bathroom
Sleeps 4
Match: Sleeps
More info
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Whitetail Spur - Panoramic Valley View!, vacation rental in Wytheville
Whitetail Spur - Panoramic Valley View!, vacation rental in Wytheville
Whitetail Spur - Panoramic Valley View!, vacation rental in Wytheville

Whitetail Spur - Panoramic Valley View!

Rental Home
3 bedrooms
3 bathrooms
Sleeps 7
Match: Sleeps
More info
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Jacuzzi Tub, River Access, Gorgeous Views, vacation rental in Wytheville
Jacuzzi Tub, River Access, Gorgeous Views, vacation rental in Wytheville
Jacuzzi Tub, River Access, Gorgeous Views, vacation rental in Wytheville

Jacuzzi Tub, River Access, Gorgeous Views

Rental Home
2 bedrooms
1 bathroom
Sleeps 2
Match: Sleeps
More info
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The Farmhouse at Elk Creek, vacation rental in Wytheville
The Farmhouse at Elk Creek, vacation rental in Wytheville
The Farmhouse at Elk Creek, vacation rental in Wytheville

The Farmhouse at Elk Creek

Rental Home
3 bedrooms
1 bathroom
Sleeps 6
Match: Sleeps
More info
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Waterfront on New River, Reunions, Family, vacation rental in Wytheville
Waterfront on New River, Reunions, Family, vacation rental in Wytheville
Waterfront on New River, Reunions, Family, vacation rental in Wytheville

Waterfront on New River, Reunions, Family

Rental Home
4 bedrooms
2 bathrooms
Sleeps 10
Match: Sleeps
More info
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Great for family getaway!, vacation rental in Wytheville
Great for family getaway!, vacation rental in Wytheville
Great for family getaway!, vacation rental in Wytheville

Great for family getaway!

Rental Home
4 bedrooms
4 bathrooms
Sleeps 6
Match: Sleeps
More info
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AMAZING Views of Claytor Lake - 4 Bedroom Gorgeous Log Home, vacation rental in Wytheville
AMAZING Views of Claytor Lake - 4 Bedroom Gorgeous Log Home, vacation rental in Wytheville
AMAZING Views of Claytor Lake - 4 Bedroom Gorgeous Log Home, vacation rental in Wytheville

AMAZING Views of Claytor Lake - 4 Bedroom Gorgeous Log Home

Rental Home
5 bedrooms
4 bathrooms
Sleeps 8
Match: Sleeps
More info
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Gorgeous Waterfront Lodge on New River - Anisidi Lodge - Sleeps 8, vacation rental in Wytheville
Gorgeous Waterfront Lodge on New River - Anisidi Lodge - Sleeps 8, vacation rental in Wytheville
Gorgeous Waterfront Lodge on New River - Anisidi Lodge - Sleeps 8, vacation rental in Wytheville

Gorgeous Waterfront Lodge on New River - Anisidi Lodge - Sleeps 8

Rental Home
4 bedrooms
2 bathrooms
Sleeps 8
Match: Sleeps
More info
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Black Bear River Front Cabin, vacation rental in Wytheville
Black Bear River Front Cabin, vacation rental in Wytheville
Black Bear River Front Cabin, vacation rental in Wytheville

Black Bear River Front Cabin

Rental Home
3 bedrooms
3 bathrooms
Sleeps 6
Match: Sleeps
More info
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Blue Heron Rivefront Cabin, vacation rental in Wytheville
Blue Heron Rivefront Cabin, vacation rental in Wytheville
Blue Heron Rivefront Cabin, vacation rental in Wytheville

Blue Heron Rivefront Cabin

Rental Home
3 bedrooms
3 bathrooms
Sleeps 6
Match: Sleeps
More info
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Large Jacuzzi Tub, Fire Pit by River, Screened Porch, vacation rental in Wytheville
Large Jacuzzi Tub, Fire Pit by River, Screened Porch, vacation rental in Wytheville
Large Jacuzzi Tub, Fire Pit by River, Screened Porch, vacation rental in Wytheville

Large Jacuzzi Tub, Fire Pit by River, Screened Porch

Rental Home
2 bedrooms
1 bathroom
Sleeps 4
Match: Sleeps
More info
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Small Tiny Cabin Waterfront on New River, vacation rental in Wytheville
Small Tiny Cabin Waterfront on New River, vacation rental in Wytheville
Small Tiny Cabin Waterfront on New River, vacation rental in Wytheville

Small Tiny Cabin Waterfront on New River

Rental Home
2 bedrooms
1 bathroom
Sleeps 2
Match: Sleeps
More info
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NEW! Quaint Getaway w/ Indoor Pool & Gas Grill!, vacation rental in Wytheville
NEW! Quaint Getaway w/ Indoor Pool & Gas Grill!, vacation rental in Wytheville
NEW! Quaint Getaway w/ Indoor Pool & Gas Grill!, vacation rental in Wytheville

NEW! Quaint Getaway w/ Indoor Pool & Gas Grill!

Rental Home
2 bedrooms
2 bathrooms
Sleeps 6
Match: Sleeps
More info
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Gorgeous River Front Home w/ Large Flat Yard 3BR/S8, vacation rental in Wytheville
Gorgeous River Front Home w/ Large Flat Yard 3BR/S8, vacation rental in Wytheville
Gorgeous River Front Home w/ Large Flat Yard 3BR/S8, vacation rental in Wytheville

Gorgeous River Front Home w/ Large Flat Yard 3BR/S8

Rental Home
4 bedrooms
2 bathrooms
Sleeps 8
Match: Sleeps
More info
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River Trail Lodge - S14, vacation rental in Wytheville
River Trail Lodge - S14, vacation rental in Wytheville
River Trail Lodge - S14, vacation rental in Wytheville

River Trail Lodge - S14

Rental Home
5 bedrooms
4 bathrooms
Sleeps 14
Match: Sleeps
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Great for families, fishing retreat, girls weekend. Waterfront on New River, vacation rental in Wytheville
Great for families, fishing retreat, girls weekend. Waterfront on New River, vacation rental in Wytheville
Great for families, fishing retreat, girls weekend. Waterfront on New River, vacation rental in Wytheville

Great for families, fishing retreat, girls weekend. Waterfront on New River

Rental Home
4 bedrooms
2 bathrooms
Sleeps 6
Match: Sleeps
More info
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Ayita - Small cabin nestled away on the New River Trail and New River, vacation rental in Wytheville
Ayita - Small cabin nestled away on the New River Trail and New River, vacation rental in Wytheville
Ayita - Small cabin nestled away on the New River Trail and New River, vacation rental in Wytheville

Ayita - Small cabin nestled away on the New River Trail and New River

Rental Home
3 bedrooms
1 bathroom
Sleeps 4
Match: Sleeps
More info
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Waterfront on New River, Fireplace, Jacuzzi, vacation rental in Wytheville
Waterfront on New River, Fireplace, Jacuzzi, vacation rental in Wytheville
Waterfront on New River, Fireplace, Jacuzzi, vacation rental in Wytheville

Waterfront on New River, Fireplace, Jacuzzi

Rental Home
2 bedrooms
1 bathroom
Sleeps 2
Match: Sleeps
More info
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Cozy, Romantic Cabin Waterfront on the New River, vacation rental in Wytheville
Cozy, Romantic Cabin Waterfront on the New River, vacation rental in Wytheville
Cozy, Romantic Cabin Waterfront on the New River, vacation rental in Wytheville

Cozy, Romantic Cabin Waterfront on the New River

Rental Home
2 bedrooms
1 bathroom
Sleeps 2
Match: Sleeps
More info
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Tentrr Signature Site - Water's Edge Campsite on Sunset Cove, vacation rental in Wytheville
Tentrr Signature Site - Water's Edge Campsite on Sunset Cove, vacation rental in Wytheville
Tentrr Signature Site - Water's Edge Campsite on Sunset Cove, vacation rental in Wytheville

Tentrr Signature Site - Water's Edge Campsite on Sunset Cove

Rental Home
1 bedroom
1 bathroom
Sleeps 4
Match: Sleeps
More info
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Private Mountain Lake Retreat (handicap accessible), vacation rental in Wytheville
Private Mountain Lake Retreat (handicap accessible), vacation rental in Wytheville
Private Mountain Lake Retreat (handicap accessible), vacation rental in Wytheville

Private Mountain Lake Retreat (handicap accessible)

Rental Home
3 bedrooms
4 bathrooms
Sleeps 13
Match: Sleeps
More info
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