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Pickens Vacation Rentals

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51 rentals in Pickens.
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Peace-in-the-Forest Retreat - Singles, Couples, Artists, Forest Lovers, vacation rental in Pickens

Peace-in-the-Forest Retreat - Singles, Couples, Artists, Forest Lovers

1 bedroom
2 bathrooms
Sleeps 4
Match: Sleeps
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Gorgeous, Peaceful Cabin near Table Rock and Caesars Head State Parks., vacation rental in Pickens

Gorgeous, Peaceful Cabin near Table Rock and Caesars Head State Parks.

3 bedrooms
2 bathrooms
Sleeps 6
Match: Sleeps
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Our Slice of Heaven with a view in North Pickens near Table Rock State Park, vacation rental in Pickens

Our Slice of Heaven with a view in North Pickens near Table Rock State Park

2 bedrooms
1 bathroom
Sleeps 8
Match: Sleeps
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On the Oolenoy River, vacation rental in Pickens

On the Oolenoy River

2 bedrooms
1 bathroom
Sleeps 4
Match: Sleeps
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Rustic Cabin on the River, vacation rental in Pickens

Rustic Cabin on the River

3 bedrooms
1 bathroom
Sleeps 6
Match: Sleeps
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The French Cottage, vacation rental in Pickens

The French Cottage

1 bedroom
1 bathroom
Sleeps 2
Match: Sleeps
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NEW! Pickens Cabin w/ Spacious Kitchen & Dining!, vacation rental in Pickens

NEW! Pickens Cabin w/ Spacious Kitchen & Dining!

6 bedrooms
4 bathrooms
Sleeps 14
Match: Sleeps
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Pumpkintown Mountain Condos, vacation rental in Pickens

Pumpkintown Mountain Condos

1 bedroom
2 bathrooms
Sleeps 4
Match: Sleeps
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Nestled in the Foothills of the Blue Ridge Mountains., vacation rental in Pickens

Nestled in the Foothills of the Blue Ridge Mountains.

3 bedrooms
2 bathrooms
Sleeps 2
Match: Sleeps
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Hidden Gem - Privacy, Tranquility, vacation rental in Pickens

Hidden Gem - Privacy, Tranquility

2 bedrooms
1 bathroom
Sleeps 4
Match: Sleeps
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Greene Lodge on Lake Keowee, lakefront w/2 docks, close to Clemson University, vacation rental in Pickens

Greene Lodge on Lake Keowee, lakefront w/2 docks, close to Clemson University

6 bedrooms
4 bathrooms
Sleeps 20
Match: Sleeps
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Charming Lake Keowee Retreat, 16 miles from Clemson!, vacation rental in Pickens

Charming Lake Keowee Retreat, 16 miles from Clemson!

2 bedrooms
1 bathroom
Sleeps 5
Match: Sleeps
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JUST 2 SUMMER WEEKS LEFT!  Don't miss out on the Premier Lake Keowee Family Pad!, vacation rental in Pickens

JUST 2 SUMMER WEEKS LEFT! Don't miss out on the Premier Lake Keowee Family Pad!

5 bedrooms
3 bathrooms
Sleeps 16
Match: Sleeps
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Lakefront Home on Lake Keowee in Gated Community, 20 Minutes to Clemson, vacation rental in Pickens

Lakefront Home on Lake Keowee in Gated Community, 20 Minutes to Clemson

6 bedrooms
7 bathrooms
Sleeps 17
Match: Sleeps
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Creek side cottage  walking distance Of Twin Falls &  4 State Parks within 9 ml., vacation rental in Pickens

Creek side cottage walking distance Of Twin Falls & 4 State Parks within 9 ml.

3 bedrooms
2 bathrooms
Sleeps 8
Match: Sleeps
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Lake Front Chalet 9.4 miles to Clemson University, vacation rental in Pickens

Lake Front Chalet 9.4 miles to Clemson University

4 bedrooms
3 bathrooms
Sleeps 12
Match: Sleeps
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Great Multi-Generation Vacation Home on Beautiful Lake Keowee!, vacation rental in Pickens

Great Multi-Generation Vacation Home on Beautiful Lake Keowee!

5 bedrooms
4 bathrooms
Sleeps 22
Match: Sleeps
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The perfect Lake Keowee getaway!, vacation rental in Pickens

The perfect Lake Keowee getaway!

4 bedrooms
4 bathrooms
Sleeps 10
Match: Sleeps
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A Great Escape on the Lake - Amazing Mountain, Lake and Private Island views, vacation rental in Pickens

A Great Escape on the Lake - Amazing Mountain, Lake and Private Island views

5 bedrooms
5 bathrooms
Sleeps 12
Match: Sleeps
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Luxurious Rustic Log Home with Great Water Views and Sunsets!, vacation rental in Pickens

Luxurious Rustic Log Home with Great Water Views and Sunsets!

6 bedrooms
4 bathrooms
Sleeps 16
Match: Sleeps
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Brand New! Lake Keowee Retreat Near Clemson, vacation rental in Pickens

Brand New! Lake Keowee Retreat Near Clemson

2 bedrooms
2 bathrooms
Sleeps 6
Match: Sleeps
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40 Acre Cabin -farm experience with fishing, near Lake Keowee and Clemson, SC, vacation rental in Pickens

40 Acre Cabin -farm experience with fishing, near Lake Keowee and Clemson, SC

1 bedroom
1 bathroom
Sleeps 4
Match: Sleeps
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Upper Lake Keowee Waterfront!  Covered Dock/Jetports.  Mountain Serenity., vacation rental in Pickens

Upper Lake Keowee Waterfront! Covered Dock/Jetports. Mountain Serenity.

3 bedrooms
3 bathrooms
Sleeps 11
Match: Sleeps
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Golfer’s paradise for Cliffs Communities Members and their guests, vacation rental in Pickens

Golfer’s paradise for Cliffs Communities Members and their guests

5 bedrooms
5 bathrooms
Sleeps 10
Match: Sleeps
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Amazing Lake Keowee Home. Private Dock, Fire Pit, and even a Bunk House, vacation rental in Pickens

Amazing Lake Keowee Home. Private Dock, Fire Pit, and even a Bunk House

4 bedrooms
3 bathrooms
Sleeps 10
Match: Sleeps
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Country Living in the South, vacation rental in Pickens

Country Living in the South

2 bedrooms
2 bathrooms
Sleeps 4
Match: Sleeps
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Waterfront home with optional boat rental. Less than 10 miles to Clemson., vacation rental in Pickens

Waterfront home with optional boat rental. Less than 10 miles to Clemson.

5 bedrooms
5 bathrooms
Sleeps 18
Match: Sleeps
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Lake Keowee water front! Close to Clemson.  Enjoy The New Hot Tub!!!!, vacation rental in Pickens

Lake Keowee water front! Close to Clemson. Enjoy The New Hot Tub!!!!

4 bedrooms
4 bathrooms
Sleeps 12
Match: Sleeps
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TRAM AND HOT TUB ADDED!, vacation rental in Pickens

TRAM AND HOT TUB ADDED!

4 bedrooms
4 bathrooms
Sleeps 8
Match: Sleeps
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LUXE LOG CABIN, PRIVATE BOAT DOCK & HUGE VIEWS, vacation rental in Pickens

LUXE LOG CABIN, PRIVATE BOAT DOCK & HUGE VIEWS

4 bedrooms
3 bathrooms
Sleeps 10
Match: Sleeps
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Waterfront Lake Keowee chalet with Gorgeous 180° Lake Views 15 min from Clemson!, vacation rental in Pickens

Waterfront Lake Keowee chalet with Gorgeous 180° Lake Views 15 min from Clemson!

4 bedrooms
3 bathrooms
Sleeps 8
Match: Sleeps
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A Cabin in the Woods - perfect getaway! You'll Love it Here!, vacation rental in Pickens

A Cabin in the Woods - perfect getaway! You'll Love it Here!

1 bedroom
1 bathroom
Sleeps 4
Match: Sleeps
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Lakefront Home on Private Cove in Desirable Upper Lake Keowee Location, vacation rental in Pickens

Lakefront Home on Private Cove in Desirable Upper Lake Keowee Location

3 bedrooms
3 bathrooms
Sleeps 10
Match: Sleeps
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Charming Lake Front Home on Lake Keowee Waterfront with Mountain Views, vacation rental in Pickens

Charming Lake Front Home on Lake Keowee Waterfront with Mountain Views

4 bedrooms
3 bathrooms
Sleeps 12
Match: Sleeps
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Beautiful lakefront home in The Reserve at Lake Keowee, vacation rental in Pickens

Beautiful lakefront home in The Reserve at Lake Keowee

5 bedrooms
6 bathrooms
Sleeps 16
Match: Sleeps
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Clemson Football Game Weekends!, vacation rental in Pickens

Clemson Football Game Weekends!

5 bedrooms
3 bathrooms
Sleeps 10
Match: Sleeps
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Your SC vacation starts here.  Stay here for a Clemson game and get much more, vacation rental in Pickens

Your SC vacation starts here. Stay here for a Clemson game and get much more

2 bedrooms
2 bathrooms
Sleeps 8
Match: Sleeps
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Rustic Sunset Escape on 67 Acres w/Outdoor Kitchen, vacation rental in Pickens

Rustic Sunset Escape on 67 Acres w/Outdoor Kitchen

3 bedrooms
2 bathrooms
Sleeps 6
Match: Sleeps
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Lake Keowee Escape w/ Dock, Deck & Lake Access!, vacation rental in Pickens

Lake Keowee Escape w/ Dock, Deck & Lake Access!

3 bedrooms
4 bathrooms
Sleeps 8
Match: Sleeps
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Bear Creek Cabin - an isolated getaway on 7 acres with a private waterfall., vacation rental in Pickens

Bear Creek Cabin - an isolated getaway on 7 acres with a private waterfall.

2 bedrooms
1 bathroom
Sleeps 6
Match: Sleeps
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Lake Keowee Condo w/ Balcony & Resort Amenities!, vacation rental in Pickens

Lake Keowee Condo w/ Balcony & Resort Amenities!

2 bedrooms
2 bathrooms
Sleeps 4
Match: Sleeps
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Clemson Game Day Getaway, vacation rental in Pickens

Clemson Game Day Getaway

4 bedrooms
3 bathrooms
Sleeps 8
Match: Sleeps
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Lake Keowee Condo w/ Views + Pools + Marina!, vacation rental in Pickens

Lake Keowee Condo w/ Views + Pools + Marina!

2 bedrooms
2 bathrooms
Sleeps 4
Match: Sleeps
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Rustic style 1 bedroom Loft getaway near Clemson, vacation rental in Pickens

Rustic style 1 bedroom Loft getaway near Clemson

1 bedroom
1 bathroom
Sleeps 4
Match: Sleeps
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Restful Creekside Retreat by Table Rock State Park, vacation rental in Pickens

Restful Creekside Retreat by Table Rock State Park

1 bedroom
1 bathroom
Sleeps 4
Match: Sleeps
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Lakefront Condo w/ Resort-Style Amenities +Marina, vacation rental in Pickens

Lakefront Condo w/ Resort-Style Amenities +Marina

2 bedrooms
2 bathrooms
Sleeps 6
Match: Sleeps
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Lake Keowee Resort Condo w/ Balcony & Pool Access!, vacation rental in Pickens

Lake Keowee Resort Condo w/ Balcony & Pool Access!

2 bedrooms
2 bathrooms
Sleeps 6
Match: Sleeps
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NEW! Lakefront Six Mile Retreat w/ Hot Tub & Dock!, vacation rental in Pickens

NEW! Lakefront Six Mile Retreat w/ Hot Tub & Dock!

4 bedrooms
3 bathrooms
Sleeps 12
Match: Sleeps
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NEW! Lake Keowee Family Townhome on the Waterfront, vacation rental in Pickens

NEW! Lake Keowee Family Townhome on the Waterfront

3 bedrooms
2 bathrooms
Sleeps 5
Match: Sleeps
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Romantic, Cozy Loft w/ Yard, 5 Miles to Clemson, vacation rental in Pickens

Romantic, Cozy Loft w/ Yard, 5 Miles to Clemson

2 bedrooms
1 bathroom
Sleeps 4
Match: Sleeps
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