We noticed that you're using an unsupported browser. The Tripadvisor website may not display properly.We support the following browsers:
Windows: Internet Explorer, Mozilla Firefox, Google Chrome. Mac: Safari.

Wesco Vacation Rentals

List your property
Owner log in
Check in
— / — / —
Check out
— / — / —
Guests
0 rooms, 2+ guests
Bedrooms
Any
Bathrooms
Any
Amenities
Show more
Suitability
Show more
Property type
Show more
Distinctive Features
Show more
Distance from
1 mi
43 rentals in Wesco.
Sort by:
Tripadvisor Sort
Revenue impacts this sort order. Learn more.

Seeking R&R or Adventure, 3Hills Cabin has it all!

Rental Home
3 bedrooms
2 bathrooms
Sleeps 10
Match: Sleeps
More info
Vrbo.com logo
Check in
Check out
Farm House on the Meramec River and 160 Acres, vacation rental in Wesco
Farm House on the Meramec River and 160 Acres, vacation rental in Wesco
Farm House on the Meramec River and 160 Acres, vacation rental in Wesco

Farm House on the Meramec River and 160 Acres

Rental Home
2 bedrooms
1 bathroom
Sleeps 8
Match: Sleeps
More info
Vrbo.com logo
Check in
Check out
Sunrise Cabin - Breathtaking Sunrises & Relaxing Sunsets, vacation rental in Wesco
Sunrise Cabin - Breathtaking Sunrises & Relaxing Sunsets, vacation rental in Wesco
Sunrise Cabin - Breathtaking Sunrises & Relaxing Sunsets, vacation rental in Wesco

Sunrise Cabin - Breathtaking Sunrises & Relaxing Sunsets

Rental Home
2 bedrooms
1 bathroom
Sleeps 4
Match: Sleeps
More info
Vrbo.com logo
Check in
Check out
New Luxury Home in Woods w/ Private Access to the Meramec River and Gravel Bar, vacation rental in Wesco
New Luxury Home in Woods w/ Private Access to the Meramec River and Gravel Bar, vacation rental in Wesco
New Luxury Home in Woods w/ Private Access to the Meramec River and Gravel Bar, vacation rental in Wesco

New Luxury Home in Woods w/ Private Access to the Meramec River and Gravel Bar

Rental Home
7 bedrooms
5 bathrooms
Sleeps 22
Match: Sleeps
More info
Vrbo.com logo
Check in
Check out
Ellen's Log Cabin with Hot Tub ~ Located Minutes From The Upper Meramec River, vacation rental in Wesco
Ellen's Log Cabin with Hot Tub ~ Located Minutes From The Upper Meramec River, vacation rental in Wesco
Ellen's Log Cabin with Hot Tub ~ Located Minutes From The Upper Meramec River, vacation rental in Wesco

Ellen's Log Cabin with Hot Tub ~ Located Minutes From The Upper Meramec River

Rental Home
4 bedrooms
3 bathrooms
Sleeps 8
Match: Sleeps
More info
Vrbo.com logo
Check in
Check out
Country Cabin on 200 Acre Cattle Farm on the Meramec River with Hot Tub, vacation rental in Wesco
Country Cabin on 200 Acre Cattle Farm on the Meramec River with Hot Tub, vacation rental in Wesco
Country Cabin on 200 Acre Cattle Farm on the Meramec River with Hot Tub, vacation rental in Wesco

Country Cabin on 200 Acre Cattle Farm on the Meramec River with Hot Tub

Rental Home
3 bedrooms
2 bathrooms
Sleeps 6
Match: Sleeps
More info
Vrbo.com logo
Check in
Check out
The Rock House - Vacation Rental in Salem Missouri, vacation rental in Wesco
The Rock House - Vacation Rental in Salem Missouri, vacation rental in Wesco
The Rock House - Vacation Rental in Salem Missouri, vacation rental in Wesco

The Rock House - Vacation Rental in Salem Missouri

Rental Home
1 bedroom
1 bathroom
Sleeps 2
Match: Sleeps
More info
Vrbo.com logo
Check in
Check out
Jack's Log Cabin Near Meramec River in Quiet Wooded Setting With Hot Tub, vacation rental in Wesco
Jack's Log Cabin Near Meramec River in Quiet Wooded Setting With Hot Tub, vacation rental in Wesco
Jack's Log Cabin Near Meramec River in Quiet Wooded Setting With Hot Tub, vacation rental in Wesco

Jack's Log Cabin Near Meramec River in Quiet Wooded Setting With Hot Tub

Rental Home
1 bedroom
1 bathroom
Sleeps 2
Match: Sleeps
More info
Vrbo.com logo
Check in
Check out
'For Old Time's Sake' Log Cabin, vacation rental in Wesco
'For Old Time's Sake' Log Cabin, vacation rental in Wesco
'For Old Time's Sake' Log Cabin, vacation rental in Wesco

'For Old Time's Sake' Log Cabin

Rental Home
2 bedrooms
1 bathroom
Sleeps 7
Match: Sleeps
More info
Vrbo.com logo
Check in
Check out
Get Back to Nature at Three Pine Cabin, vacation rental in Wesco
Get Back to Nature at Three Pine Cabin, vacation rental in Wesco
Get Back to Nature at Three Pine Cabin, vacation rental in Wesco

Get Back to Nature at Three Pine Cabin

Rental Home
2 bedrooms
1 bathroom
Sleeps 7
Match: Sleeps
More info
Vrbo.com logo
Check in
Check out
Save time - get the best Wesco rentals sent straight to your email!
Fully modern 'rustic' cottage., vacation rental in Wesco
Fully modern 'rustic' cottage., vacation rental in Wesco
Fully modern 'rustic' cottage., vacation rental in Wesco

Fully modern 'rustic' cottage.

Rental Home
2 bedrooms
1 bathroom
Sleeps 6
Match: Sleeps
More info
Vrbo.com logo
Check in
Check out
A Private Retreat to Escape the Busyness of Life, vacation rental in Wesco
A Private Retreat to Escape the Busyness of Life, vacation rental in Wesco
A Private Retreat to Escape the Busyness of Life, vacation rental in Wesco

A Private Retreat to Escape the Busyness of Life

Rental Home
1 bedroom
1 bathroom
Sleeps 2
Match: Sleeps
More info
Vrbo.com logo
Check in
Check out
Located In The Foothills Of The Ozarks, Enjoy A Peaceful Setting At The Lodge., vacation rental in Wesco
Located In The Foothills Of The Ozarks, Enjoy A Peaceful Setting At The Lodge., vacation rental in Wesco
Located In The Foothills Of The Ozarks, Enjoy A Peaceful Setting At The Lodge., vacation rental in Wesco

Located In The Foothills Of The Ozarks, Enjoy A Peaceful Setting At The Lodge.

Rental Home
4 bedrooms
2 bathrooms
Sleeps 12
Match: Sleeps
More info
Vrbo.com logo
Check in
Check out
Hawk's Ridge Cabin-New Custom 3 Bedroom, 2.5 Bath-14 Private Acres-1600 Sq.Ft., vacation rental in Wesco
Hawk's Ridge Cabin-New Custom 3 Bedroom, 2.5 Bath-14 Private Acres-1600 Sq.Ft., vacation rental in Wesco
Hawk's Ridge Cabin-New Custom 3 Bedroom, 2.5 Bath-14 Private Acres-1600 Sq.Ft., vacation rental in Wesco

Hawk's Ridge Cabin-New Custom 3 Bedroom, 2.5 Bath-14 Private Acres-1600 Sq.Ft.

Rental Home
3 bedrooms
3 bathrooms
Sleeps 6
Match: Sleeps
More info
Vrbo.com logo
Check in
Check out
Whippoorwill Cabin on the Upper Meramec River, vacation rental in Wesco
Whippoorwill Cabin on the Upper Meramec River, vacation rental in Wesco
Whippoorwill Cabin on the Upper Meramec River, vacation rental in Wesco

Whippoorwill Cabin on the Upper Meramec River

Rental Home
2 bedrooms
2 bathrooms
Sleeps 8
Match: Sleeps
More info
Vrbo.com logo
Check in
Check out
Fully modern and unique country lodge. Quiet and cozy., vacation rental in Wesco
Fully modern and unique country lodge. Quiet and cozy., vacation rental in Wesco
Fully modern and unique country lodge. Quiet and cozy., vacation rental in Wesco

Fully modern and unique country lodge. Quiet and cozy.

Rental Home
4 bedrooms
1 bathroom
Sleeps 10
Match: Sleeps
More info
Vrbo.com logo
Check in
Check out
Cabin at cardiac hill, vacation rental in Wesco
Cabin at cardiac hill, vacation rental in Wesco
Cabin at cardiac hill, vacation rental in Wesco

Cabin at cardiac hill

Rental Home
1 bedroom
1 bathroom
Sleeps 6
Match: Sleeps
More info
Vrbo.com logo
Check in
Check out
Maria’s Rest - Comfortable Ozark Seclusion - NEW Trails Cut!, vacation rental in Wesco
Maria’s Rest - Comfortable Ozark Seclusion - NEW Trails Cut!, vacation rental in Wesco
Maria’s Rest - Comfortable Ozark Seclusion - NEW Trails Cut!, vacation rental in Wesco

Maria’s Rest - Comfortable Ozark Seclusion - NEW Trails Cut!

Rental Home
2 bedrooms
1 bathroom
Sleeps 6
Match: Sleeps
More info
Vrbo.com logo
Check in
Check out
Koi Cottage With Mineral Hot Tub ~ Located Minutes From The Upper Meramec River, vacation rental in Wesco
Koi Cottage With Mineral Hot Tub ~ Located Minutes From The Upper Meramec River, vacation rental in Wesco
Koi Cottage With Mineral Hot Tub ~ Located Minutes From The Upper Meramec River, vacation rental in Wesco

Koi Cottage With Mineral Hot Tub ~ Located Minutes From The Upper Meramec River

Rental Home
1 bedroom
2 bathrooms
Sleeps 4
Match: Sleeps
More info
Vrbo.com logo
Check in
Check out
Hillside Cabin on 200 Acre Working Cattle Farm on the Meramec River, vacation rental in Wesco
Hillside Cabin on 200 Acre Working Cattle Farm on the Meramec River, vacation rental in Wesco
Hillside Cabin on 200 Acre Working Cattle Farm on the Meramec River, vacation rental in Wesco

Hillside Cabin on 200 Acre Working Cattle Farm on the Meramec River

Rental Home
2 bedrooms
1 bathroom
Sleeps 6
Match: Sleeps
More info
Vrbo.com logo
Check in
Check out
Private Lake Paradise, vacation rental in Wesco
Private Lake Paradise, vacation rental in Wesco
Private Lake Paradise, vacation rental in Wesco

Private Lake Paradise

Rental Home
4 bedrooms
4 bathrooms
Sleeps 13
Match: Sleeps
More info
Vrbo.com logo
Check in
Check out
Driftwood River Lodge on the Meramec River. Steelville, MO., vacation rental in Wesco
Driftwood River Lodge on the Meramec River. Steelville, MO., vacation rental in Wesco
Driftwood River Lodge on the Meramec River. Steelville, MO., vacation rental in Wesco

Driftwood River Lodge on the Meramec River. Steelville, MO.

Rental Home
4 bedrooms
3 bathrooms
Sleeps 13
Match: Sleeps
More info
Vrbo.com logo
Check in
Check out
Let this early 1900’s country farmhouse take you back in time! Now available!!!, vacation rental in Wesco
Let this early 1900’s country farmhouse take you back in time! Now available!!!, vacation rental in Wesco
Let this early 1900’s country farmhouse take you back in time! Now available!!!, vacation rental in Wesco

Let this early 1900’s country farmhouse take you back in time! Now available!!!

Rental Home
2 bedrooms
2 bathrooms
Sleeps 6
Match: Sleeps
More info
Vrbo.com logo
Check in
Check out
Secluded farmhouse retreat - Meramec river access!, vacation rental in Wesco
Secluded farmhouse retreat - Meramec river access!, vacation rental in Wesco
Secluded farmhouse retreat - Meramec river access!, vacation rental in Wesco

Secluded farmhouse retreat - Meramec river access!

Rental Home
4 bedrooms
2 bathrooms
Sleeps 12
Match: Sleeps
More info
Vrbo.com logo
Check in
Check out
Getaway Cabin next door to Maramec Spring Park & Meramec River Trophy Trout, vacation rental in Wesco
Getaway Cabin next door to Maramec Spring Park & Meramec River Trophy Trout, vacation rental in Wesco
Getaway Cabin next door to Maramec Spring Park & Meramec River Trophy Trout, vacation rental in Wesco

Getaway Cabin next door to Maramec Spring Park & Meramec River Trophy Trout

Rental Home
3 bedrooms
1 bathroom
Sleeps 9
Match: Sleeps
More info
Vrbo.com logo
Check in
Check out
Cabin near Meramec River & Maramec Spring Park - Private Vacation Cabin, vacation rental in Wesco
Cabin near Meramec River & Maramec Spring Park - Private Vacation Cabin, vacation rental in Wesco
Cabin near Meramec River & Maramec Spring Park - Private Vacation Cabin, vacation rental in Wesco

Cabin near Meramec River & Maramec Spring Park - Private Vacation Cabin

Rental Home
2 bedrooms
2 bathrooms
Sleeps 8
Match: Sleeps
More info
Vrbo.com logo
Check in
Check out
Pine Valley at Dillard Mill - Cozy Cottage, vacation rental in Wesco
Pine Valley at Dillard Mill - Cozy Cottage, vacation rental in Wesco
Pine Valley at Dillard Mill - Cozy Cottage, vacation rental in Wesco

Pine Valley at Dillard Mill - Cozy Cottage

Rental Home
1 bedroom
1 bathroom
Sleeps 4
Match: Sleeps
More info
Vrbo.com logo
Check in
Check out
The Wildflower - Near Huzzah and Bass Resort, vacation rental in Wesco
The Wildflower - Near Huzzah and Bass Resort, vacation rental in Wesco
The Wildflower - Near Huzzah and Bass Resort, vacation rental in Wesco

The Wildflower - Near Huzzah and Bass Resort

Rental Home
4 bedrooms
2 bathrooms
Sleeps 12
Match: Sleeps
More info
Vrbo.com logo
Check in
Check out
Herons Landing at Driftwood River Lodge on the Meramec River, vacation rental in Wesco
Herons Landing at Driftwood River Lodge on the Meramec River, vacation rental in Wesco
Herons Landing at Driftwood River Lodge on the Meramec River, vacation rental in Wesco

Herons Landing at Driftwood River Lodge on the Meramec River

Rental Home
3 bedrooms
2 bathrooms
Sleeps 13
Match: Sleeps
More info
Vrbo.com logo
Check in
Check out
NEW LISTING!! Private Cottage GetAway, vacation rental in Wesco
NEW LISTING!! Private Cottage GetAway, vacation rental in Wesco
NEW LISTING!! Private Cottage GetAway, vacation rental in Wesco

NEW LISTING!! Private Cottage GetAway

Rental Home
1 bedroom
1 bathroom
Sleeps 4
Match: Sleeps
More info
Vrbo.com logo
Check in
Check out
Copperstone Cottage - A Romantic Escape, vacation rental in Wesco
Copperstone Cottage - A Romantic Escape, vacation rental in Wesco
Copperstone Cottage - A Romantic Escape, vacation rental in Wesco

Copperstone Cottage - A Romantic Escape

Cabin
1 bedroom
1 bathroom
Sleeps 2
Match: Sleeps
More info
Check in
Check out
Payment Protection
Pine Valley at Dillard Mill - Airsteam w/ Outdoor Tub, vacation rental in Wesco
Pine Valley at Dillard Mill - Airsteam w/ Outdoor Tub, vacation rental in Wesco
Pine Valley at Dillard Mill - Airsteam w/ Outdoor Tub, vacation rental in Wesco

Pine Valley at Dillard Mill - Airsteam w/ Outdoor Tub

Rental Home
1 bedroom
1 bathroom
Sleeps 2
Match: Sleeps
More info
Vrbo.com logo
Check in
Check out
Comfortable 1 Bedroom Cabin with Added Loft, Full Kitchen & LIving Area, vacation rental in Wesco
Comfortable 1 Bedroom Cabin with Added Loft, Full Kitchen & LIving Area, vacation rental in Wesco
Comfortable 1 Bedroom Cabin with Added Loft, Full Kitchen & LIving Area, vacation rental in Wesco

Comfortable 1 Bedroom Cabin with Added Loft, Full Kitchen & LIving Area

Rental Home
1 bedroom
1 bathroom
Sleeps 4
Match: Sleeps
More info
Vrbo.com logo
Check in
Check out
NEW! Historic, Salem Home: Fit for Large Groups!, vacation rental in Wesco
NEW! Historic, Salem Home: Fit for Large Groups!, vacation rental in Wesco
NEW! Historic, Salem Home: Fit for Large Groups!, vacation rental in Wesco

NEW! Historic, Salem Home: Fit for Large Groups!

Rental Home
7 bedrooms
3 bathrooms
Sleeps 12
Match: Sleeps
More info
Vrbo.com logo
Check in
Check out
Murphy's Retreat-Beautiful view with  river access, vacation rental in Wesco
Murphy's Retreat-Beautiful view with  river access, vacation rental in Wesco
Murphy's Retreat-Beautiful view with  river access, vacation rental in Wesco

Murphy's Retreat-Beautiful view with river access

Rental Home
3 bedrooms
3 bathrooms
Sleeps 12
Match: Sleeps
More info
Check in
Check out
Payment Protection
Hilltop Cabin Overlooking the Meramec River, vacation rental in Wesco
Hilltop Cabin Overlooking the Meramec River, vacation rental in Wesco
Hilltop Cabin Overlooking the Meramec River, vacation rental in Wesco

Hilltop Cabin Overlooking the Meramec River

Rental Home
2 bedrooms
1 bathroom
Sleeps 8
Match: Sleeps
More info
Vrbo.com logo
Check in
Check out
Spacious but cozy farmstead lodge has stone fireplace and sleeping for 9 to 10, vacation rental in Wesco
Spacious but cozy farmstead lodge has stone fireplace and sleeping for 9 to 10, vacation rental in Wesco
Spacious but cozy farmstead lodge has stone fireplace and sleeping for 9 to 10, vacation rental in Wesco

Spacious but cozy farmstead lodge has stone fireplace and sleeping for 9 to 10

Condo/Apartment
0 bedrooms
1 bathroom
Sleeps 10
Match: Sleeps
More info
Vrbo.com logo
Check in
Check out
Sassafras Cabin-perfect for 4 to 6!   HOT TUB, vacation rental in Wesco
Sassafras Cabin-perfect for 4 to 6!   HOT TUB, vacation rental in Wesco
Sassafras Cabin-perfect for 4 to 6!   HOT TUB, vacation rental in Wesco

Sassafras Cabin-perfect for 4 to 6! HOT TUB

Cabin
2 bedrooms
1 bathroom
Sleeps 6
Match: Sleeps
More info
Check in
Check out
Payment Protection
Dogwood Cabin-Western romance at its best!, vacation rental in Wesco
Dogwood Cabin-Western romance at its best!, vacation rental in Wesco
Dogwood Cabin-Western romance at its best!, vacation rental in Wesco

Dogwood Cabin-Western romance at its best!

Cabin
3 bedrooms
2 bathrooms
Sleeps 8
Match: Sleeps
More info
Check in
Check out
Payment Protection
SAVE, MO, vacation rental in Wesco
SAVE, MO, vacation rental in Wesco
SAVE, MO, vacation rental in Wesco

SAVE, MO

Rental Home
1 bedroom
1 bathroom
Sleeps 4
Match: Sleeps
More info
Check in
Check out
Payment Protection
Rent My Farm House, vacation rental in Wesco
Rent My Farm House, vacation rental in Wesco
Rent My Farm House, vacation rental in Wesco

Rent My Farm House

Rental Home
2 bedrooms
1 bathroom
Sleeps 8
Match: Sleeps
More info
Check in
Check out
Payment Protection
Little Wolf at Indian Springs on the Upper Meramec River, vacation rental in Wesco
Little Wolf at Indian Springs on the Upper Meramec River, vacation rental in Wesco
Little Wolf at Indian Springs on the Upper Meramec River, vacation rental in Wesco

Little Wolf at Indian Springs on the Upper Meramec River

Rental Home
1 bedroom
1 bathroom
Sleeps 5
Match: Sleeps
More info
Vrbo.com logo
Check in
Check out
A Luxury King Suite Cabin in the Ozarks, vacation rental in Wesco
A Luxury King Suite Cabin in the Ozarks, vacation rental in Wesco
A Luxury King Suite Cabin in the Ozarks, vacation rental in Wesco

A Luxury King Suite Cabin in the Ozarks

Rental Home
1 bedroom
1 bathroom
Sleeps 3
Match: Sleeps
More info
Vrbo.com logo
Check in
Check out
Farm House on the Meramec River and 160 Acres (Private), vacation rental in Wesco
Farm House on the Meramec River and 160 Acres (Private), vacation rental in Wesco
Farm House on the Meramec River and 160 Acres (Private), vacation rental in Wesco

Farm House on the Meramec River and 160 Acres (Private)

Rental Home
2 bedrooms
1 bathroom
Sleeps 1
More info
Vrbo.com logo
Check in
Check out
PreviousNext
1
Frequently Asked Questions about Wesco