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Saint Charles Vacation Rentals

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49 rentals in Saint Charles.
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Perfect for your vacation stay in Historic St. Charles! Near Main Street, vacation rental in Saint Charles

Perfect for your vacation stay in Historic St. Charles! Near Main Street

3 bedrooms
2 bathrooms
Sleeps 6
Match: Sleeps
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Amazing 1860's Historic Home!, vacation rental in Saint Charles

Amazing 1860's Historic Home!

2 bedrooms
1 bathroom
Sleeps 6
Match: Sleeps
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1920's Vintage Home in Historic Saint Charles - Fully Remodeled, vacation rental in Saint Charles

1920's Vintage Home in Historic Saint Charles - Fully Remodeled

3 bedrooms
2 bathrooms
Sleeps 8
Match: Sleeps
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Vintage French Beauty - Newly Renovated & Spacious, vacation rental in Saint Charles

Vintage French Beauty - Newly Renovated & Spacious

3 bedrooms
2 bathrooms
Sleeps 8
Match: Sleeps
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Clark Brick House w/ Pool - Historic St. Charles, vacation rental in Saint Charles

Clark Brick House w/ Pool - Historic St. Charles

3 bedrooms
3 bathrooms
Sleeps 9
Match: Sleeps
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St. Charles 1860's Gem - Sleeps 8!, vacation rental in Saint Charles

St. Charles 1860's Gem - Sleeps 8!

2 bedrooms
1 bathroom
Sleeps 8
Match: Sleeps
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Residence on the Roundabout, vacation rental in Saint Charles

Residence on the Roundabout

2 bedrooms
1 bathroom
Sleeps 4
Match: Sleeps
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Huge Renovated Historic Schoolhouse w/Hidden Room!, vacation rental in Saint Charles

Huge Renovated Historic Schoolhouse w/Hidden Room!

4 bedrooms
3 bathrooms
Sleeps 12
Match: Sleeps
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Quiet St Charles Cottage w/ Patio & 4 Acres, vacation rental in Saint Charles

Quiet St Charles Cottage w/ Patio & 4 Acres

2 bedrooms
2 bathrooms
Sleeps 8
Match: Sleeps
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The brick and Morgan: History Meets Modern Brick Home in St. Charles near Main, vacation rental in Saint Charles

The brick and Morgan: History Meets Modern Brick Home in St. Charles near Main

2 bedrooms
1 bathroom
Sleeps 6
Match: Sleeps
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French Town St. Charles. Walk to Main St/MO River, vacation rental in Saint Charles

French Town St. Charles. Walk to Main St/MO River

3 bedrooms
2 bathrooms
Sleeps 16
Match: Sleeps
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CLEAN St. Charles Central Oasis*Pets/kids/Groups/2 CAR Garage, vacation rental in Saint Charles

CLEAN St. Charles Central Oasis*Pets/kids/Groups/2 CAR Garage

4 bedrooms
3 bathrooms
Sleeps 16
Match: Sleeps
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4 Bedroom Centrally Located West St Louis County, vacation rental in Saint Charles

4 Bedroom Centrally Located West St Louis County

4 bedrooms
2 bathrooms
Sleeps 8
Match: Sleeps
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Perfect Weekend Getaway! Condo With Great River Views! Pool!, vacation rental in Saint Charles

Perfect Weekend Getaway! Condo With Great River Views! Pool!

1 bedroom
1 bathroom
Sleeps 2
Match: Sleeps
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Grafton Getaway-Farmhouse on 2 wooded acres 1/2 mile from Main Street, vacation rental in Saint Charles

Grafton Getaway-Farmhouse on 2 wooded acres 1/2 mile from Main Street

3 bedrooms
1 bathroom
Sleeps 10
Match: Sleeps
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A perfect weekend gateway!, vacation rental in Saint Charles

A perfect weekend gateway!

3 bedrooms
3 bathrooms
Sleeps 8
Match: Sleeps
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Gorgeous, Spacious, 4 Bedroom - Great Location!, vacation rental in Saint Charles

Gorgeous, Spacious, 4 Bedroom - Great Location!

4 bedrooms
3 bathrooms
Sleeps 8
Match: Sleeps
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The Bungalow Walkout, vacation rental in Saint Charles

The Bungalow Walkout

1 bedroom
1 bathroom
Sleeps 4
Match: Sleeps
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West County Gem - Easy access to STL attractions!, vacation rental in Saint Charles

West County Gem - Easy access to STL attractions!

3 bedrooms
2 bathrooms
Sleeps 8
Match: Sleeps
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Charming house minutes away from downtown Kirkwood, vacation rental in Saint Charles

Charming house minutes away from downtown Kirkwood

3 bedrooms
2 bathrooms
Sleeps 6
Match: Sleeps
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(55.1S) True St. Louis Experience!, vacation rental in Saint Charles

(55.1S) True St. Louis Experience!

2 bedrooms
1 bathroom
Sleeps 5
Match: Sleeps
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Quaint Arts and Crafts Five Room Flat, vacation rental in Saint Charles

Quaint Arts and Crafts Five Room Flat

2 bedrooms
1 bathroom
Sleeps 3
Match: Sleeps
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Classy 2Bed 1bath Condo by Forest Park, WashU & The Delmar Loop in St Louis!, vacation rental in Saint Charles

Classy 2Bed 1bath Condo by Forest Park, WashU & The Delmar Loop in St Louis!

2 bedrooms
1 bathroom
Sleeps 8
Match: Sleeps
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The Grafton Beach House, vacation rental in Saint Charles

The Grafton Beach House

1 bedroom
1 bathroom
Sleeps 5
Match: Sleeps
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Spacious 2BR 1BA by Forest Park, Washington University & The Delmar Loop!, vacation rental in Saint Charles

Spacious 2BR 1BA by Forest Park, Washington University & The Delmar Loop!

2 bedrooms
1 bathroom
Sleeps 8
Match: Sleeps
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Elegant, Spacious Home in Historic Dogtown STL, vacation rental in Saint Charles

Elegant, Spacious Home in Historic Dogtown STL

2 bedrooms
1 bathroom
Sleeps 6
Match: Sleeps
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Artsy 1BR/1BA near Forest Park, Washington University & The Delmar Loop!, vacation rental in Saint Charles

Artsy 1BR/1BA near Forest Park, Washington University & The Delmar Loop!

1 bedroom
1 bathroom
Sleeps 6
Match: Sleeps
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Entire 2Bed 1Bath Condo by Forest Park, WashU & The Delamar Loop in St Louis, vacation rental in Saint Charles

Entire 2Bed 1Bath Condo by Forest Park, WashU & The Delamar Loop in St Louis

2 bedrooms
1 bathroom
Sleeps 6
Match: Sleeps
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Suite Jane - private complete 2 bedroom apartment in historical village, vacation rental in Saint Charles

Suite Jane - private complete 2 bedroom apartment in historical village

2 bedrooms
1 bathroom
Sleeps 6
Match: Sleeps
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FAMILY SUITE 2Bd, 1Ba near Forest Park, Wash U and The Delmar Loop, vacation rental in Saint Charles

FAMILY SUITE 2Bd, 1Ba near Forest Park, Wash U and The Delmar Loop

2 bedrooms
1 bathroom
Sleeps 8
Match: Sleeps
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(53.1N) Walk To Forest Park In Comfort!, vacation rental in Saint Charles

(53.1N) Walk To Forest Park In Comfort!

1 bedroom
1 bathroom
Sleeps 4
Match: Sleeps
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Updated Brick Home Sleep 9 Walk to WashU/Barnes/Delmar Loop/Forest Park/Zoo, vacation rental in Saint Charles

Updated Brick Home Sleep 9 Walk to WashU/Barnes/Delmar Loop/Forest Park/Zoo

3 bedrooms
2 bathrooms
Sleeps 9
Match: Sleeps
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Special Mar pricing! ~Great location book now~ T, vacation rental in Saint Charles

Special Mar pricing! ~Great location book now~ T

2 bedrooms
1 bathroom
Sleeps 6
Match: Sleeps
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Backyard BBQ Hidden Gem~Groups/Kids/Pets Welcome, vacation rental in Saint Charles

Backyard BBQ Hidden Gem~Groups/Kids/Pets Welcome

4 bedrooms
2 bathrooms
Sleeps 16
Match: Sleeps
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Everything you need for a wonderful visit to STL!, vacation rental in Saint Charles

Everything you need for a wonderful visit to STL!

2 bedrooms
1 bathroom
Sleeps 6
Match: Sleeps
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Free Breakfast. Pool & Gym. Near Progress West Hospital!, vacation rental in Saint Charles

Free Breakfast. Pool & Gym. Near Progress West Hospital!

1 bedroom
1 bathroom
Sleeps 6
Match: Sleeps
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Your home away from home, vacation rental in Saint Charles

Your home away from home

1 bedroom
1 bathroom
Sleeps 2
Match: Sleeps
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Lovely condo fully remodeled just minutes from West Port Plaza, vacation rental in Saint Charles

Lovely condo fully remodeled just minutes from West Port Plaza

2 bedrooms
1 bathroom
Sleeps 4
Match: Sleeps
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Comfy 2Br/1Ba Near Forest Park, Wash U & The Delmar Loop!, vacation rental in Saint Charles

Comfy 2Br/1Ba Near Forest Park, Wash U & The Delmar Loop!

2 bedrooms
1 bathroom
Sleeps 6
Match: Sleeps
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Upgraded brick house, Sleep 9, Walk to WashU/Delmar Loop/Forest Park/Zoo, vacation rental in Saint Charles

Upgraded brick house, Sleep 9, Walk to WashU/Delmar Loop/Forest Park/Zoo

3 bedrooms
2 bathrooms
Sleeps 9
Match: Sleeps
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updated 1 bedroom condo in secure building, vacation rental in Saint Charles

updated 1 bedroom condo in secure building

1 bedroom
1 bathroom
Sleeps 2
Match: Sleeps
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Clean, Comfortable and Cozy..., vacation rental in Saint Charles

Clean, Comfortable and Cozy...

1 bedroom
1 bathroom
Sleeps 4
Match: Sleeps
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Very Quite area near lots of food and shopping, vacation rental in Saint Charles

Very Quite area near lots of food and shopping

2 bedrooms
2 bathrooms
Sleeps 4
Match: Sleeps
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Group-Friendly Duplex – 5 Bedrooms, Great for 2 Families or Large Groups, vacation rental in Saint Charles

Group-Friendly Duplex – 5 Bedrooms, Great for 2 Families or Large Groups

5 bedrooms
2 bathrooms
Sleeps 14
Match: Sleeps
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All new cozy Guest Nest Luxe (Unit A), vacation rental in Saint Charles

All new cozy Guest Nest Luxe (Unit A)

2 bedrooms
1 bathroom
Sleeps 4
Match: Sleeps
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All New Cozy Guest Nest home mins from the airport -Extended Stay  (Unit B), vacation rental in Saint Charles

All New Cozy Guest Nest home mins from the airport -Extended Stay (Unit B)

2 bedrooms
1 bathroom
Sleeps 4
Match: Sleeps
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Da Lux, vacation rental in Saint Charles

Da Lux

2 bedrooms
1 bathroom
Sleeps 4
Match: Sleeps
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Coco Channel, vacation rental in Saint Charles

Coco Channel

1 bedroom
1 bathroom
Sleeps 2
Match: Sleeps
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Historic Brick Home By Forest Park / Wash U., vacation rental in Saint Charles

Historic Brick Home By Forest Park / Wash U.

4 bedrooms
4 bathrooms
Sleeps 14
Match: Sleeps
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