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There are two forms of public transport to get to and away from Reinosa, bus or train.
There is a regular bus service from Santander to Reinosa every hour during the day. This comprises of two versions of the same line, the quicker buses (taking an hour and a half), which go up the A67 motorway and only stop in Torrelavega and Los Corrales, and the slightly slower buses (taking around 20 minutes longer) which go up the old N611 and stop in all the villages along the way. They alternate hourly throughout the day. There are fewer buses at the weekend. In Reinosa these buses can be caught either from the bus station itself, from outside the church in the centre of town,from outside the secondary school, from the ringroad near the hospital, and from outside the Mercadona supermarket. Tickets are available from the driver of the bus, just say where you want to go.
Reinosa is on the main RENFE train line from Santander to Madrid, and is served by 2 long distance trains every day. It takes 3-4 hours to get to Madrid (via Palencia and Valladolid amongst others), and the morning train continues on to Alicante (7 hours). RENFE also run fairly regular (8 per weekday, less at weekends) local trains called Cercanias which run from Santander to Reinosa, stopping at many villages on the way. The journey time is around an hour and a half. There are two train stations in Reinosa, the main station next to the bus station, and the smaller Rio Ebro station, close to the Dia supermarket, which is only served by Cercanias trains. If travelling from the main station (or from Santander or Torrelavega main stations) tickets should be bought before boarding the train. If you board at a smaller station with no ticket booth they can be bought on the train itself from the guard.