Interstate 15 runs along the east side of Helena, northward toward Great Falls and southward toward Butte. It intersects with U.S. Highways 12/287 which run east-west and extends toward East Helena.

Helena Regional Airport is located 2.5 miles from the center of the city. SkyWest, Comair, Horizon, Northwest, and Big Sky Airlines provide 14 daily flights to the city. 2850 Skyway Drive, Helena, MT 59602, (406)442-2821.

Bus service is provided by Rimrock Trailways , 3100 US Highway 12 East, Helena , MT 59601 , (406)442-5860 which connects with Greyhound.