There is a terrific nightlife scene in Gainesville, Georgia.  The downtown square offers a wide variety of nightlife within walking distance.  The locals are very friendly.

 

The Monkey Barrel is a great place for live entertainment.  They serve gourmet pizza and have a wonderful selection of beers on tap. 

The piano bar at Luna's restaurant also offers fun even if more sedate. The downstairs bar in Poor Richards is always lively, as is the food there. They have the best steaks in town. Gainesville is home to Road Atlanta and the training facilities of the Atlanta Falcons in near by Flowery Branch. Lanier Raceway offers stock car racing. For Italian, visit Biba's and enjoy their big food and gourmet selections. They have a full bar and extensive wine list. Lake Lanier rowing club often stages regatas and races on the weekends drawing visitors from all over the country if not the world to their fine facility. Plus with many theatrical productions there always seems to be a play going on somewhere.