The Basilica of the Shrine of the Immaculate Conception located on Michigan Ave NW is worth the trip for the religious artwork it contains.  Visitors don't have to share any particular religious viewpoint to appreciate the treasures within.  Over the years the Shrine has added several chapels from Ireland, Africa, Poland, and other countries, providing some insight into the religious viewpoint of each country.  The tour is worth the time spent visiting 70 chapels/shrine sites in 60 minutes, including the lower level containing crypts and the original church, along with gift shop, bookstore, and dining room which were added later.
Plan to spend some time at the Shrine and book store.  Although not mentioned under accommodations listed on the Shrine's web page, there is a good-sized dining room located on the lower level.  Be advised prices are a little high and the menu is ala carte.  The web page also indicates the site is wheelchair accessible and there is an elevator inside the main entrance door atrium area.  Parking is free but may be a little hard to find whenever there is a scheduled mass or event going on so plan ahead.