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a trip to Wiesbaden (45 minutes via train), the posh spa/casino town or Mainz (40 minutes via subway) with a lovely old town and the world-famous Gutenberg Museum
a trip to the picturesque town of Idstein (45 minutes via train or car from downtown Frankfurt or the airport). The town's high school is located in the 400 year old castle. No castle ruins here, just the real deal. Also the beautifully restored "little castle" is now a 4 star hotel (Hoerhof hotel/restaurant) featuring fine dining. Big savings can be had lodging in this centrally located town versus staying in the larger towns without loosing the convenience or accessibility to the other locations listed here as day trips. If you are visiting in Spring, don't miss the Jazz festival. Three days of music from more than 30 bands. Music for anyones taste can be found.
a trip to the moutainous Taunus region with many lovely spa towns and castle ruins (Bad Homburg the biggest one with the great Taunus Therme; Kronberg; Königstein, Hofheim, as well as an open-air zoo, the Opel Zoo); all towns are within a 25 minute reach via train
a trip to the Rhein (45 minutes) via train ride to Rüdesheim (extremely touristy) and Bingen, take a boat trip on the river, visit the Loreley or a train ride along the UNESCO wolrd heritage sight Rhine valley to Koblenz
a trip to the wine country Rheingau along the Bundesstrasse with must-see towns such as Eltville and Johannisberg, as well as castles such as Kloster Eberbach and Schloss Vollrads (all with excellent restaurants); it is highly recommended to rent a car (30 minutes to Eltville)
a day trip to Heidelberg (a one-way tour takes one hour via train)
a day trip to Baden-Baden (northern rim of the Black Forest), which takes about 70 minutes by train
a train ride to the beautiful Lahn towns of Marburg (student town), Limburg (historical cathedral city) and Butzbach(Fachwerk); about 75 minutes via train
a train ride to Würzburg with the UNESCO World Heritage Site Residenz and a nice student town atmosphere (about 70 minutes via train). Würzburg also has some fabulous wineries, try the white wines; perhaps even a side excursion to the walled-town of Rothenburg-ob-der-Tauber (2.5 hour train ride with many stops)
a train ride to Darmstadt (20 minutes fast train, 45 minutes slow train) to see the art nouveau district and the rose garden.
a 30 minute drive to the medieval Ronneburg (maybe even during the medieval Easter and Christmas markets)
a 75 minute drive to Michelstadt in the Odenwald region, a beautiful town that also has a very popular Christmas market
visit Aschaffenburg (about 30 minutes by car and maybe 35 minute by train)