Pastrami on rye with mustard - just do it. I can't vouch for any of the other sandwiches - but the pastrami is fantastic. They offer 3 different sizes, so I would go with the small unless you're not planning on eating anything else all day. They offer a full selection of Dr. Brown's soda - cream soda is my favorite pairing. David's is a block from the A/C at Nostrand and also a block from the LIRR stop at Nostrand well worth a trip to Brooklyn. In fact it's also on the same subway line as Mile End in Boerum Hill (so you could make it a double pastrami day). As for the ambiance - there are a few tables, not a place that I would linger, but fine for a lunch.
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