86th Street on the Lexington subway line (4,5,6) is an inevitability if museums are involved. OK, there are other ways to get there but the majority will get to walk from 86th Street and Lex. through the residential section of the Upper East Side for the Guggenheim, Met. Museum, the Neue Gallerie, the Frick collection, and a few other cultural icons. It's called Museum Mile along Fifth Avenue. The Upper East Side also has Hunter College, various Commercial Galleries and a bevy of small museums. Walking from the subway to the Met. Museum, however, gives me enough of the residential side of UES to satisfy any curiosity I might have..