We stayed at Gaslamp Plaza Suites for a full week. My wife attended a conference at the convention center (I played!). We stayed in a basic mini-suite. Bed was comfortable, room size was OK. Overall - it was a great VALUE. Clean, comfortable, great location for dining, nightlife and sight seeing. We could easily walk to the convention center (10 minutes) or the waterfront (Midway, Hornblower, etc). For the more advertuous, get a transit pass and use mass transit to sightsee. Yes - there are homeless folks wandering about, but leave them alone, they'll leave you alone. I went out to La Jolla, Torrey Pines, Coronado and Old Town using mass transit - very easy. DO NOT RENT A CAR. Parking appears to be expensive and dicey.
Sean at the front desk was very helpful!
Breakfast on the roof is OK. View is great, but it really is just coffee and toast/danish.More