These ladies were on my list of 'must-see' while in San Fran and they were really pretty indeed.
I stayed in Union Square, so the walk here via Market St > Hayes St was a long, long, long but lovely walk. It took a bit over half an hour and the streets were steep. Along Hayes St there are plenty of cafes and boutique shops to stop and browse at.
Once there, the whole area was lovely and the Painted Ladies are just as pretty as you see in photos. Alamo Square is also a dog park so there will be dogs running around.
On my walk back I drop by City Hall, cutting through Civic Center Plaza before making my way back to Union Square.