Along with the 99 this road was the original western border to border road. Starts out at the Mexican border and terminates at the Canadian border. Most of the road in SoCal is overlaid with the I-15. There are older portions that are still drivable between Escondido, through Temecula/Murrieta. 395 branches off the I-15 in Hesperia, and runs along the base of the eastern Sierra Nevada mountains. Crossing into Nevada at Topaz lake continues North through Reno until entering California again. Be careful around Minden, NV (speed trap). We departed the 395 in Susanville and continued towards Bend via the 139. The views along the Eastern Sierra are great, even better when they are snow-capped. There is a lot to see and do along this highway. Makes a good option if you want to avoid the I-5. Less traffic and is 4 lane for the majority of the route to Reno.
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