My wife and I decided to go to Vegas and knew we did not want to stay at a hotel casino. We just wanted to get back to where we were staying and not have to walk through a casino to get to an elevator. We stayed in Tower 2 of the Signature. When I booked the room I had asked for a high floor with a view of the Strip (Las Vegas Blvd). We ended up on the 24th floor looking down Harmon. From our room we could see the Center City and Polo Tower pretty well as well as the Hilton Grand Vacations. There was a place to get a pretty good breakfast in the lobby of tower 2 for Las Vegas pricing. Not cheap, but not terrible. Concierge service was good there as well and they helped us to get some tickets for a few shows we wanted to see.
The nice thing about the Signature is that it is attached to the MGM Grand Casino through a series of hallways. We were able to use the casino as a shortcut to get to NYNY and other places a bit further south on the strip. The Signature is about two blocks (long blocks) off the strip right near Center City. Lots of things are within waling distance, but be sure you add enough time to get where you are going. A walk to Ceasars for example was about 20 minutes.
We stayed at the owner suites, so they are actually managed by a different group called Luxury Suites international and they handle all cleaning and servicing of the rooms. It is not a big deal, but if you need more towels or something call them the day before to make sure you get what you need. There is valet parking that is free...you should tip of course and for some reason it took a good amount of time, maybe ten minutes or so, to get the car. Even at 430 in the morning when we were leaving to get our flight. So be ready for that as well. It is a gated hotel, which your key card will get you in when you check in. Just let the gate house guy now you are checking in and they will confirm on a list...
Overall I would definitely go back here and stay there! Enjoy!!