I have stayed at the Lowes many times over the years. It is one of the best locations you can ask for as it has direct beach access, no need to pack a bag/ cross the street. It is near food, shopping, coffee shops, good bakery one block north on Collins, (La Provance) friendly staff, great pool, comfortable beds. It seems on the pricey side but rooms are quiet with cable, movies on demand, good room service. Wifi is an extra 15 bucks a day in your room, should be free as this is a more expensive hotel, but its free in the lobby if you don't mind schlepping down there.
Overall my favorite hotel in Miami for convenience and comfort.