Writing a review for Colorado Boulevard is difficult due to the tremendous size of the area covered. I will limit this review to the area I know best - the portion of Colorado Boulevard in Pasadena.
From West to East, the first portion of Colorado Boulevard would be in the Old Town Pasadena area. The center of Old Town is really the intersection of Colorado Boulevard and Fair Oaks. In this general area there are several good Italian restaurants such as Mi Piace (my favorite), Louise's Trattoria, and Il Fornaio (see my other reviews for these 3). Also there is The Cheescake Factory, 35er (a good dive bar), Barney's Beanery (a good bar with a bad name), 21 Choices (a really popular frozen yogurt place - just look for the long line). Also some drinking and dancing places in this area.
If you head east from here (near Marengo Ave) on your right will be BJ's Brewery (good food & good beer) and the Paseo Colorado Mall. Upstairs at Paseo there is the Arclight movie theatre as well as a number of restaurants such as The Yard House (nice sports bar), Porto Alegre (Brazillian churrascaria) and a few more places such as El Cholo (Mexican food). Across the street on the other side of Colorado is Ruth's Chris Steakhouse (haven't been here but heard it is expensive but delicious).
A bit further east is Roys Restaurant (near El Molino Ave) which according to this website is the #1 restaurant in Pasadena. Someday, when I find a big bag full of money lying in the street, I will try it.
Heading further east (near Lake Ave) is Nine and Nine Thai (really good Thai food), Chilly Mango (also really good Thai food), Indochine (Vietnamese food) and Lovebirds Cafe (sandwiches and bakery items).
Obviously with several miles to cover I could not mention every place. You may want to explore this area further.
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