We walked around this area for a while on our trip. While it was an interesting area, the shopping street is basically the same as most shopping streets in European cities. So if you do feel like window shopping, it's probably OK, but if you want culture or attractions, there's not as much going on.
Near the northeastern end is Taksim square. It's not very interesting, frankly, but there are a few statues and flags. Near the southern part of the district is the Galata Tower. That's definitely worth a look if it's a clear day (or night), since it's got views of the old town.
Do avoid going on the Tünel "subway" thing, though. It's literally about 60 seconds, and while the price is already too high, they apparently overcharged us, but when we went back to try to ask for an explanation, the guy at the window wasn't helpful at all. In the end, just walk up the hill, since it'll be good to burn off some vacation food calories.
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