The Firenze ticket is the way to go for all the major museums in Florence unless you enjoy waiting in line.
Walking through the long hall with Michelangelo's unfinished slaves and pieta, and then seeing the David at the end is a very powerful experience. I'm an artist and was very happy to sit and draw Michelangelo's masterpiece for a couple of hours before seeing the rest of the museum.
Don't miss the Dutch exhibit: there are some wonderful pieces to see. I was especially happy to be able to get close enough to see brushstrokes in the adequately lit spaces. The protective glass over the paintings allows viewers to get close without fear of damaging the art. As an artist, I really appreciate being able to do that.
Be sure to pack along a water bottle and a granola bar or something for sustenance. I didn't see any kind of snack bar at the museum and as is typical in the whole city, there are no public water fountains.
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