I stayed two nights together with my girlfriend in this lovely hotel. Don´t let the two star rating of the hotel fool you. Although the building itself is 500 years old and there is no elevator available, the staff itself more than compensates for that. The service they offer is exceptional - from pointing you to the nearest sight seeing locations to giving good advice on traditional restaurants with fair prices up to the absolutely fantastic breakfast that is delivered right to your room (which is by the way pretty big for this price range).
The hotel is only about 5 to 10 minutes by foot away from the central train station (Termini), where also all the trains and buses head to right from the airport. And you can reach most of the famous spots (like the Colosseum, Forum Romanum, Pantheon, Piazza die Spagna, ...) from the hotel either by foot or from the bus station that is located right at the front door.
The only negative thing I can say, is that the hotel is situated at the third floor and there is no elevator available. But it was actually not such a big deal for me/us.
If you are looking for a lovely little hotel, with great service and fantastic price-performance ratio, don´t look any further - you found it :)More