I spent two nights at the Residenz 2000 (which changed its name recently) because of its close proximity to the nearby research facilities, where I had to work long hours and start early - I figured I would not have spare time to visit the city, which by the way I know very well, since I lived there for many years. I would never stay in this part of town if I came as a tourist. On the plus side, the residential area where the hotel is located is calm and quiet.
Upon check-in the reception was unable to find my reservation, but since they had one room left, it did not matter. I had made the mistake to pre-order parking, which is not necessary in this part of town, very expensive in this hotel, and inconvenient because of the weird construction of the parking garage (you can read about it elsewhere).
The hotel looks modern from the outside, and tries to convey the message to be stylish. A closer look in my room revealed severe maintenance problems - a missing AC outlet, a broken shower door, two burned out light bulbs and a badly configured WLAN, which would only work from the lobby but not from the room. I have rarely seen so many maintenance issues in one hotel room. The staff was rather clueless about these problems; I cannot help but wonder if the hotel management had any formal training at all. The hotel itself has potential, the rooms are quiet, and with better maintenance and a management knowing how to actually run a hotel, the place might become a decent hotel. In its current state, however, it is unlikely that I'll return.
One last thing: There is a restaurant next to the hotel, but a much better place is "Il Mulino", a 5 minute walk close to the S-Bahn station Lichterfelde West.