Went with children, mostly due to the praises here on Tripadvisor, and we weren't disappointed.
It's enormous and takes a whole day easily, especially with kids, since much of it is very hands-on and people spend ages testing things out. Our kids loved the trains, while husband and I adored the photo- and video sections. You can try using a Camera Obscura, chase after holograms and see some extremely rare footage, like the execution of Mary Queen of Scots! (properly labeled as disturbing, mind you.)
Do go. Berlin is so much more than just the War and the Wall, and this gets a bit overlooked sometimes.