The stretch is a busy one, particularly in the summer months, but it's definitely worth it. Just make sure you give lots of time for travel: in the summer there's lots of cars, in the winter there's lots of snow.
For those with the patience, you'll be rewarded with breathtaking views of mountains, ice fields and of course plenty of animals. It takes a little time, but definitely stop by the Athabasca Glacier and walk around. Avoid the Brewster trucks, low value and long lines, in my opinion.
I've only done it a few times, buy I find the winter drive most interesting. That being said, keep in mind that while Parks Canada maintains the road, it's definitely a secondary route with limited services. Pack some provisions, just in case.