How can I get from Winatche Wa. to Eugene Or. in one day?
You could fly Alaska Air (Horizon) from Wenatchee to Seattle, then Seattle to Eugene. I found a fare for $111 one way, if you book far enough out. http://alaskaair.com/
Jann, you could drive it not that big of a deal, just leave early in the morning.
Highway 97 then just follow the signs through Ellensburg and on down to OR.
Long day but very doable.