We will be driving to Myrtle beach from Cincinnati, OH and am looking for the best route. Mapquest has given different routes each time we loaded in our destination. One has us going 75 South, the other has us going through West Virginia. Any idea the quickest and best route? We will be stopping about halfway or slightly before the mountains and the driving the remainder of the way the following morning. Any suggestions on where to stop with the route you are suggesting?