We stayed at the Hotel Granvia. It's right in the Shinkansen station, so couldn't be easier if you're travelling with luggage. The rooms were very quiet, reasonable size, and we even had a pod coffee machine. Lovely :)
We stayed at the Sheraton, we had a HUGE room on the 19th floor, the view was stunning, plus it has covered walkway access direct into the station.
If you have more luggage than you can comfortably carry, it's best to stay near the train station.
If you prefer to be in a more lively area, stay near the Hondori trolley station.
Once you've picked the area, TripAdvisor ratings would be a reasonable guide for choosing a hotel.
Thank you for your responses. I was thinking close to the train as we want to do a lot of touristy things and day trips. I will have a look into the above suggestions!
As cheapskates we stayed in Urbain Central. We had JR passes giving free Meipurupu buses, and used these to get around, including returning to the station at end of our stay. The free software drinks were welcome with the high temperatures
Close to the train: Granvia or Sheraton. Sometimes the rates are very good.
I have also used the ANA Crowne as the location near the peace park and the certral district is also good - but pick the room type to suit.
As you are travelling with others (parents), do not pick a hotel with tiny rooms APA are known for being some of the tiniest and the one mentioned above has 10m2 rooms (I normally look for double that size).
You didn't post a budget so you are getting varying suggestions.
I wouldn't stay at APA either--it's not one of the better-run chains when it comes to budget business hotels.
We have stayed at Hotel Sunroute, very reasonable price and I chose that hotel as it is right opposite the peace park and museum. I knew my sister would want to spend a lot of time at the museum and park and also that she isn't comfortable travelling around alone. Staying at Sunroute she was fine just crossing the road to the park and museum and knew she couldn't get herself lost.
I have on other trips stayed at Okayama for a few days, using it as a base for day travel using the JR pass.
Easier than moving on each few days and the shinkansen is so fast.
I have learnt to have as few as possible hotel moves, replaced with day trips.