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Malaria Tablets - Arco

London, United...
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Malaria Tablets - Arco

Hi,

I'm hoping someone could please shed some light.

I'm travelling to Kenya soon and wondering whether anyone has taken malaria tablets bought from Kenya. The specific ones I am referring to are called ARCO which is made up of Artemisinin-naphthoquine.

Any information would be much appreciated.

Thank you

Rai

Washington DC...
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1. Re: Malaria Tablets - Arco

Is this combination actually used as a prophylaxis or is it for treatment? Not that it means much but I haven't seen this combo listed for malaria prevention.

Mtwapa, Kenya
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for Barcelona, Newcastle upon Tyne, Bamburi, Mtwapa
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2. Re: Malaria Tablets - Arco

Hi,

Arco is not a prophylaxis drug, ie it is not used to prevent people being infected with malaria, if that is what you are asking. It is a treatment for people who have been diagnosed as having malaria especially resistant strain malaria.

If you want more info see http://www.ngcplc.com/arco/

London, United...
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3. Re: Malaria Tablets - Arco

Hi,

Thank you for your replies. I meant for prevention hence, an alternative to Malarone or Malanil.

Does this mean it cannot be taken as preventing drug like Malarone or Malanil?

London, United...
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4. Re: Malaria Tablets - Arco

Hi,

Thank you for your replies. I meant for prevention hence, an alternative to Malarone or Malanil.

Does this mean it cannot be taken as preventing drug like Malarone or Malanil?

Washington DC...
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5. Re: Malaria Tablets - Arco

Rai27, as I mentioned earlier, I haven't seen ARCO used for preventative purposes. The usual candidates are Lariam, doxycycline (doxy) and Malarone. Lariam and doxy will be less expensive than Malarone, but Lariam can have some significant (as in ruin one's holiday) side effects. I suggest getting together with your doctor and deciding on which one would be appropriate for you.

Edited: 4:25 pm, June 11, 2013
London, United...
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6. Re: Malaria Tablets - Arco

Thanks Steveb108 - the ones you mention are the ones I've also heard off.

Thank you for your reply.

Hamburg, Germany
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7. Re: Malaria Tablets - Arco

To my knowledge each and every sort of malaria pill available today is working like a treatment measure. So there is no pill yet worth to be called prophylaxis.

Would love to be refuted here ... ;-)

Washington DC...
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8. Re: Malaria Tablets - Arco

Prophylaxis is any medical or public health procedure whose purpose is to prevent, rather than treat or cure, a disease or other medical issue. Perhaps as an example that can be taken as similar to malaria prophylaxis, people with abnormal heart valves have a high risk of developing heart valve infections even after only minor surgery. This happens because bacteria from other parts of the body get into the bloodstream during surgery and travel to the heart valves. To prevent these infections, people with heart valve problems often take antibiotics before having any kind of surgery, including simple dental work. So antibiotics are preventing the bacteria from causing an infection, while the antimalarials do the same. In either case, that satisfies the definition of prophylaxis.

Mtwapa, Kenya
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9. Re: Malaria Tablets - Arco

Malarone is used primarily as a causal prophylactic, it operates against the first stage of the parasite's life cycle in the host's liver and therefore prevents infection spreading to the blood.

Doxycycline and Lariam are suppressive prophylactics. they operate once infection has taken place and the parasite has started the second phase of reproduction in the hosts blood stream. they kill the parasites as they enter the blood stream, preventing them multiplying further.

They are taken as a daily (or weekly in the case of lariam) dosage for the extent of the exposure to risk.

These are currently the only drugs recommended for malaria prevention in Sub-saharan Africa

There do not seem to be any suggestions that Arco could be used in this way. It seems it is designed exclusively to treat established cases of malaria by killing the parasites in the blood in a single curative dose (of 8 tablets in a single day), it does not appear to be designed for ongoing usage.

Sheffield, United...
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10. Re: Malaria Tablets - Arco

Hi, Artemesinin based drugs should not, indeed MUST NOT be used as a prophylaxis.

Artemesinin is the only drug currently effective against malaria, BUT it has a half life in the body of only 4 hrs, during which it will destroy MOST of the parasites PRESENT in the body, and is therefore no use against potential infections, (the other ingredient is longer lasting, to "finish off" the remaining parasites) Unlimited use of Artemesinin as a prophylaxis is already threatening its effectiveness, as infections gained after its effective period gives the parasite chance to become resistant. Our friends the Chinese are to thank for that as they persist in using it as a prophylaxis.

For an informative ((and amusing) read on the subject of malaria and its prevention/cure see

thesurgeryuganda.org/Dr.Stockley%20Eye%20art…

(ignore the references to Uganda, the facts apply everywhere) Note that Dr Stockley is a real tropical disease specialist, and has been awarded the MBE for his services to medicine. Note also the W.H.O. have tried to get countries to restrict Artemesinin drugs to TREATMENT only

Ivan

Edited: 7:17 am, June 12, 2013
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