I would certainly suggest that you eat at Rusty's Riverfront Grill (on Washington St) while in Vicksburg.
The Delta Blues Museum and the Catshead blues gift shop in Clarksdale are certainly worth a visit. You might want to stop in at The Ground Zero blues club---you never know, sometimes you will hear live blues during lunch time.
In Tunica, the Riverfront Museum is very interesting and has a magnificent view of the Mississippi River. The Hollywood Café in Tunica is one of our favorite places to eat in Tunica (This is not at the Hollywood Casino.)
Where are you staying in Tunica?
Have a safe and fun trip.
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