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Why Go Now: This under-the-radar province is emerging as Eastern Europe’s newest wine region. Ninety-four percent of the Czech Republic’s burgeoning wine production (Grüner Veltliner and Cabernet Moravia) comes from its rolling vineyards and castle-topped towns. The regional capital, Brno, in the center of Moravia, is dotted with Modernist houses designed by Adolf Loos and Ludwig Mies van der Rohe (the creator of the famous Brno chair) and is the perfect jumping-off point for exploring the area.
The Details: Stay at the new nautical-themed Noem Arch Hotel (doubles from $141), with 18 cabin-like rooms and a blue-walled restaurant that blends harmoniously with the glass aquariums. Farther south, in Mikulov, the village's Jewish heritage is the inspiration for artist Sylva Chludilova’s paintings at Galerie Efram. In neighboring Valtice, sample an extensive wine selection at Narodni Salon Vin, in the town château.