We took the ETN bus from Mexico City to Guanajuato, very comfortable and interesting 5 hour ride with rest rooms on board, movies, etc. Much cheaper and pretty convenient.
Hotel Luna's very nice.
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Do you know which hotel is across the street from Domo de la Feria?????
I wonder if you know that there is an international airport in Leon, Guanajuato. It's called El Bajio or BJX. It would be more simple to fly there than to make a trek all the way from the capital to Guanajuato.