We noticed that you're using an unsupported browser. The TripAdvisor website may not display properly.We support the following browsers:
Windows: Internet Explorer, Mozilla Firefox, Google Chrome. Mac: Safari.

Rx Restaurant and Bar

421 Castle St, Wilmington, NC 28401-5141
+1 910-399-3080
Map updates are paused. Zoom in to see updated info.
Reset zoom
Updating Map...
  • Excellent70%
  • Very good21%
  • Average7%
  • Poor1%
  • Terrible1%
Travelers talk about
“brunch” (22 reviews)
“pig ears” (18 reviews)
“duck” (20 reviews)
Closed Now
All hours
American, Vegetarian Friendly, Gluten Free Options
$$ - $$$
421 Castle St, Wilmington, NC 28401-5141
All Details
Write a ReviewReviews (224)
Traveler rating
Traveler type
Time of year

41 - 50 of 223 reviews

Reviewed October 23, 2016 via mobile

Delicious coffee, fresh squeezed orange juice, tiny buttery biscuits, perfectly cooked Montecristo and French toast. Their staff was friendly and kind.

Thank ncdabco
Reviewed October 21, 2016 via mobile

Even though we live in the Raleigh NC area we come to Wilmington often and have eaten at many of their finest restaurants over the years. Rx is my favorite of all. The kale Caesar salad with a chicken fried egg was incredible as was...More

Thank Pam C
Reviewed October 10, 2016

My nephew, a transplant from NYC and a true foodie, recommended this as his favorite restaurant. We LOVE Husk and all things Sean Brock-this chef worked with Sean. Excellent food, excellent service-the bartender even wrote down his butternut Old Fashioned recipe for me- excellent food....More

Thank Diane D
Reviewed September 22, 2016 via mobile

One would never expect to find such a restaurant in the area. But find we did. Menu changes daily, so never the same experience twice. Husband had pork shoulder and I had the pasta entree. All ingredients were ultra fresh and well prepared. Sara, our...More

Thank Bonnie222
Reviewed September 15, 2016

On the basis of our recent visit, I would rate this among the top 8-10 restaurants in Wilmington. We went on a Tuesday, when glasses of wine were half-price. And they have some good choices, at around $10/glass -- or around $5 for us: a...More

Thank Weyden
Reviewed August 31, 2016

My husband and I received a recommendation to this restaurant during our 4th of July weekend. We walked in and loved the ambiance. The staff is very friendly! Had a drink at the bar prior to dinner. Their drink menu is excellent. The bartender was...More

Thank MaryNC
Reviewed August 24, 2016

Enjoyed third visit recently and was, once again, very impressed. Love the menu and attention to detail.

Thank 764billw
Reviewed August 23, 2016

The food is consistent and excellent. Sure it's a little on the pricey side but you know that going in and if everything wasn't on-point I'd gladly tear them a new one for what's basically a small portion of meat/fish on top of some greens...More

Thank Dutch_Hawk
Reviewed August 22, 2016

We came here without reservations just before the crowd. They were nice enough to sit us at a table for two. Appetizers are most unusual, combos of pork and cheese, but very spicy. The entrees were incredible, my wife said she had the best soft...More

Thank Ronstan
Reviewed August 19, 2016 via mobile

This place is amazing. Delicious food, farm to table. Every penny well spent. Cocktails made with house made ingredients are awesome as well

Thank Josh W
Nearby Restaurants
The Peppered Cupcake
313 reviews
.52 miles away
Pilot House
632 reviews
.42 miles away
Elijah's Restaurant
1,096 reviews
.44 miles away
Nearby Attractions
Downtown Wilmington
554 reviews
.50 miles away
Bellamy Mansion
463 reviews
.54 miles away
Cape Fear Serpentarium
409 reviews
.46 miles away
Burgwin-Wright House and Gardens
80 reviews
.52 miles away
Ask a question
Questions & Answers
Cynthia F
January 18, 2015|
Response from Betsy V | Reviewed this property |
A wicked good pork belly, grits and egg dish...a twisted Monte Cristo... Eggs Benedict...buscuits and housemade peach jam, lots more...
Cynthia F
January 18, 2015|
Response from Betsy V | Reviewed this property |
Small compared to other varieties/areas I have sampled. But the minionette on the raw ones is inspired....
Improve this listing

Restaurant Details

Rating summary
  • Food
  • Value
Average prices
$30 - $30
Dinner, Lunch, Brunch, Late Night
Restaurant features
Reservations, Seating, Waitstaff, Wheelchair Accessible, Serves Alcohol, Full Bar
Dining Style
Casual Elegant
Good for
Bar scene, Romantic, Local cuisine, Special occasions, Business meetings, Families with children
Open Hours
10:00 AM - 10:00 PM
5:00 PM - 10:00 PM
5:00 PM - 10:00 PM
5:00 PM - 10:00 PM
5:00 PM - 10:30 PM
5:00 PM - 10:30 PM
Location and Contact Information
  • Address: 421 Castle St, Wilmington, NC 28401-5141
  • Location: United States  >  North Carolina (NC)  >  North Carolina Coast  >  Wilmington
  • Phone Number: +1 910-399-3080
  • E-mail
Located in the old Hall's Drugstore on 5th and Castle
Is This Your TripAdvisor Listing?
Own or manage this property? Claim your listing for free to respond to reviews, update your profile and much more. Claim Your Listing