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Rx Restaurant and Bar

Certificate of Excellence
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421 Castle St, Wilmington, NC 28401-5141
+1 910-399-3080
Sun 10:00 am - 10:00 pm
Tue - Thu 5:00 pm - 10:00 pm
Fri - Sat 5:00 pm - 10:30 pm
More Info
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200 Reviews from our TripAdvisor Community

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Time of year
Showing 199: English reviews
Poughkeepsie, NY
Level Contributor
171 reviews
81 restaurant reviews
common_n_restaurant_reviews_1bd8 66 helpful votes
Reviewed September 15, 2016

On the basis of our recent visit, I would rate this among the top 8-10 restaurants in Wilmington. We went on a Tuesday, when glasses of wine were half-price. And they have some good choices, at around $10/glass -- or around $5 for us: a Fabre Rose from Provence, a Malbec, and a Russian River Chardonnay were what we ordered.... More 

Thank Weyden
Lumberton, NC
Level Contributor
24 reviews
22 restaurant reviews
common_n_restaurant_reviews_1bd8 16 helpful votes
Reviewed August 31, 2016

My husband and I received a recommendation to this restaurant during our 4th of July weekend. We walked in and loved the ambiance. The staff is very friendly! Had a drink at the bar prior to dinner. Their drink menu is excellent. The bartender was everything you could ask for, pleasant, engaging and knowledgeable. After being seated, Rick waited on... More 

Thank MaryNC
Wilmington, North Carolina, United States
Level Contributor
12 reviews
7 restaurant reviews
common_n_restaurant_reviews_1bd8 3 helpful votes
Reviewed August 24, 2016

Enjoyed third visit recently and was, once again, very impressed. Love the menu and attention to detail.

Thank Bill W
Wilmington, North Carolina
Level Contributor
25 reviews
17 restaurant reviews
common_n_restaurant_reviews_1bd8 6 helpful votes
Reviewed August 23, 2016

The food is consistent and excellent. Sure it's a little on the pricey side but you know that going in and if everything wasn't on-point I'd gladly tear them a new one for what's basically a small portion of meat/fish on top of some greens and beans for $28/a plate but it is. The food is cooked and seasoned perfectly.... More 

Thank Dutch_Hawk
Wilmington, North Carolina
Level Contributor
16 reviews
13 restaurant reviews
common_n_restaurant_reviews_1bd8 5 helpful votes
Reviewed August 22, 2016

We came here without reservations just before the crowd. They were nice enough to sit us at a table for two. Appetizers are most unusual, combos of pork and cheese, but very spicy. The entrees were incredible, my wife said she had the best soft shell crab she ever had. I will say I had the best duck legs I... More 

Thank Ronstan
Level Contributor
11 reviews
9 restaurant reviews
Reviewed August 19, 2016 via mobile

This place is amazing. Delicious food, farm to table. Every penny well spent. Cocktails made with house made ingredients are awesome as well

Thank Josh W
Fiscardo, Greece
Level Contributor
131 reviews
67 restaurant reviews
common_n_restaurant_reviews_1bd8 40 helpful votes
Reviewed August 18, 2016

Located in an old pharmacy, RX, is sure to delight the locavore. We started with the customary pimento cheese which was delicious but it came with Rx ham which was a total delight. Other standouts for the night were a crispy flounder with warm potato salad and duck with hoppin john. We had eight dishes and each was delicious. Dessert... More 

Thank esemmes
Raleigh, North Carolina
Level Contributor
75 reviews
33 restaurant reviews
common_n_restaurant_reviews_1bd8 20 helpful votes
Reviewed August 15, 2016

The food at RX was good although a bit overpriced for what you get. There was nothing wrong with the food but for the price, there are several other choices in Wilmington that i would recommend. The service was outstanding however which made up for the meal.

Thank Chip L
Atlantic Beach, NC
Level Contributor
54 reviews
29 restaurant reviews
common_n_restaurant_reviews_1bd8 45 helpful votes
Reviewed July 30, 2016

After travelling from out of town for a concert that ended up being canceled, we decided to try a new place for dinner (we usually go to well reviewed Indochine). A friend who lives in Wilmington recommended several restaurants in the downtown area, including Rx. We chose it instead of the others because of the menu (changes daily but they... More 

Thank AB28512
wilmington, nc
Level Contributor
51 reviews
42 restaurant reviews
common_n_restaurant_reviews_1bd8 19 helpful votes
Reviewed July 5, 2016

Great food, simple menu. Have always had great service. A little on the pricey side, but it is well worth it. Have tried the Tile fish, the duck and the steak. All were great with tasty sides. Have also tried the pork belly app and the buffalo pig ears. All I can tell you is don't knock either until you... More 

Thank sailfishnc

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Restaurant Details

Rating summary
  • Food
    4.5 of 5 bubbles
    4.5 of 5 bubbles
  • Value
    4 of 5 bubbles
    4 of 5 bubbles
Average prices
$30 - $30
American, Gluten Free Options
Lunch, Dinner, Brunch, Late Night
Restaurant features
Reservations, Seating, Waitstaff, Serves Alcohol, Full Bar, Wheelchair Accessible
Dining Style
Casual Elegant
Good for
Romantic, Bar scene, Special occasions, Local cuisine, Families with children
Open Hours
10:00 am - 10:00 pm
5:00 pm - 10:00 pm
5:00 pm - 10:00 pm
5:00 pm - 10:00 pm
5:00 pm - 10:30 pm
5:00 pm - 10:30 pm
Location and Contact Information
  • Address: 421 Castle St, Wilmington, NC 28401-5141
  • Location: United States  >  North Carolina (NC)  >  North Carolina Coast  >  Wilmington
  • Phone Number: +1 910-399-3080
Located in the old Hall's Drugstore on 5th and Castle

Questions & Answers

Here's what previous visitors have asked, with answers from representatives of Rx Restaurant and Bar and other visitors
2 questions
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Kingsport, Tennessee, United States
over a year ago
Kingsport, Tennessee, United States
over a year ago

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Questions? Get answers from Rx Restaurant and Bar staff and past visitors.
Posting guidelines
Typical questions asked:
  • Do you have gluten-free options?
  • Is there a dress code?
  • Do you allow dogs on the outdoor patio?