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Rx Restaurant and Bar

421 Castle St, Wilmington, NC 28401-5141
+1 910-399-3080
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  • Excellent70%
  • Very good21%
  • Average7%
  • Poor1%
  • Terrible1%
Travelers talk about
“brunch” (22 reviews)
“pig ears” (18 reviews)
“duck” (20 reviews)
Open Now
5:00 PM - 10:30 PMAll hours
American, Vegetarian Friendly, Gluten Free Options
$$ - $$$
421 Castle St, Wilmington, NC 28401-5141
All Details
Write a ReviewReviews (224)
Traveler rating
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Time of year

1 - 10 of 223 reviews

Reviewed 5 days ago

You can tell this is a real "Locals Go To" as we were there at opening for brunch on Sunday 12/10/17 along with nearly 30 other people that appeared to know this place as regulars. Service was excellent. Strong, robust coffee. Shared the smoked chicken...More

Thank TotalPerfection
Reviewed 4 weeks ago

I chose this restaurant to celebrate my mother's birthday, while visiting the Wilmington area. We were able to receive a call in advance and the menu was customized to mention the celebration of the special occasion. The food and customer service provided is great. The...More

Thank Boris E
Reviewed 5 weeks ago

We had a great meal here. I had the Humble Roots Grilled Chicken which sounds boring, but it was amazing. Great service, look forward to going back when I am in Wilmington

Thank Tony L
Reviewed 5 weeks ago

Having tried several Wilmington restaurant recommendations we keep returning to RX. The menu is limited and locally sourced and that's the plus. Nothing is more scary than thumbing through pages of a menu where likely nothing is well prepared or fresh. We took friends from...More

Thank travl80
Reviewed November 8, 2017 via mobile

I tried this at the recommendation of an actor friend who said it was a favorite of his while he was here. It's got an awesome atmosphere set in an old pharmacy. I tried it the first time for brunch. It didn't disappoint taste wise....More

1  Thank MelissaClaire93
Reviewed November 6, 2017

We have friends who told us about Rx, so we made reservations. It was a fabulous experience all around! Even my children (9, 12) were both pleased. We had the pigs ears appetizer -- be adventurous and try it. If you didn't know, you'd think...More

Thank Rachael D
Reviewed October 31, 2017 via mobile

Ate here at the recommendation of my daughter, this is a must try. Away from the bustle of downtown, which was perfect. We did the special, two dinners for $80 and was not disappointed. Server was super attentive, friendly, and knew when to give us...More

Thank Dave W
Reviewed October 26, 2017 via mobile

We had the great pleasure of celebrating my wife’s birthday here at Rx. They printed menus with a happy birthday wish for my wife, what a great way to start a meal😀 The menu offered tonight had nice choices of appetizers and main dishes My...More

Thank Bill T
Reviewed October 25, 2017

Great and inventive dinner. Diners were mostly locals from the neighborhood. Atmosphere was low key and comfortable. Service at both the bar and at our table was excellent. Would definitely return.

Thank dl53
Reviewed October 20, 2017 via mobile

We have been dining here since 2013, the food was mediocre at best. We asked the server if the restaurant had changed ownership, she said no but one of the owners (exec chef) left and opened a new place in town called Pembroke. This place...More

Thank Lucien7212
Nearby Restaurants
The Peppered Cupcake
313 reviews
.52 miles away
Pilot House
633 reviews
.42 miles away
Elijah's Restaurant
1,098 reviews
.44 miles away
Nearby Attractions
Downtown Wilmington
556 reviews
.50 miles away
Bellamy Mansion
463 reviews
.54 miles away
Cape Fear Serpentarium
409 reviews
.46 miles away
Burgwin-Wright House and Gardens
80 reviews
.52 miles away
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Questions & Answers
Cynthia F
January 18, 2015|
Response from Betsy V | Reviewed this property |
A wicked good pork belly, grits and egg dish...a twisted Monte Cristo... Eggs Benedict...buscuits and housemade peach jam, lots more...
Cynthia F
January 18, 2015|
Response from Betsy V | Reviewed this property |
Small compared to other varieties/areas I have sampled. But the minionette on the raw ones is inspired....
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Restaurant Details

Rating summary
  • Food
  • Value
Average prices
$30 - $30
Dinner, Lunch, Brunch, Late Night
Restaurant features
Reservations, Seating, Waitstaff, Wheelchair Accessible, Serves Alcohol, Full Bar
Dining Style
Casual Elegant
Good for
Romantic, Business meetings, Bar scene, Families with children, Special occasions, Local cuisine
Open Hours
10:00 AM - 10:00 PM
5:00 PM - 10:00 PM
5:00 PM - 10:00 PM
5:00 PM - 10:00 PM
5:00 PM - 10:30 PM
5:00 PM - 10:30 PM
Location and Contact Information
  • Address: 421 Castle St, Wilmington, NC 28401-5141
  • Location: United States  >  North Carolina (NC)  >  North Carolina Coast  >  Wilmington
  • Phone Number: +1 910-399-3080
  • E-mail
Located in the old Hall's Drugstore on 5th and Castle
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