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Rx Restaurant and Bar

421 Castle St, Wilmington, NC 28401-5141
+1 910-399-3080
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  • Excellent69%
  • Very good22%
  • Average7%
  • Poor1%
  • Terrible1%
Travelers talk about
“brunch” (17 reviews)
“pig ears” (18 reviews)
“duck” (20 reviews)
Closed Now
All hours
American, Vegetarian Friendly, Gluten Free Options
$$ - $$$
421 Castle St, Wilmington, NC 28401-5141
All Details
Write a ReviewReviews (226)
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1 - 10 of 225 reviews

Reviewed 5 days ago via mobile

Most enjoyable. I rarely try Shrimp & Grits ..only because I make "the best" according to my guests. Loved the oyster mushroom addition. Good Bloody Mary, good app (pig ears) surprised myself! Tiny tea biscuits. Friendly server.

Thank Suzanne M
Reviewed 1 week ago via mobile

We went to RX Friday evening and was very disappointed. This is the 2nd time in 2 months we have gone and now our last. We brought another couple who had never been and they too did not care for it. Shrimp and Grits were...More

Thank Guitarboy314
Reviewed December 11, 2017

You can tell this is a real "Locals Go To" as we were there at opening for brunch on Sunday 12/10/17 along with nearly 30 other people that appeared to know this place as regulars. Service was excellent. Strong, robust coffee. Shared the smoked chicken...More

Thank TotalPerfection
Reviewed November 17, 2017

I chose this restaurant to celebrate my mother's birthday, while visiting the Wilmington area. We were able to receive a call in advance and the menu was customized to mention the celebration of the special occasion. The food and customer service provided is great. The...More

Thank Boris E
Reviewed November 11, 2017

We had a great meal here. I had the Humble Roots Grilled Chicken which sounds boring, but it was amazing. Great service, look forward to going back when I am in Wilmington

Thank Tony L
Reviewed November 11, 2017

Having tried several Wilmington restaurant recommendations we keep returning to RX. The menu is limited and locally sourced and that's the plus. Nothing is more scary than thumbing through pages of a menu where likely nothing is well prepared or fresh. We took friends from...More

Thank travl80
Reviewed November 8, 2017 via mobile

I tried this at the recommendation of an actor friend who said it was a favorite of his while he was here. It's got an awesome atmosphere set in an old pharmacy. I tried it the first time for brunch. It didn't disappoint taste wise....More

2  Thank MelissaClaire93
Reviewed November 6, 2017

We have friends who told us about Rx, so we made reservations. It was a fabulous experience all around! Even my children (9, 12) were both pleased. We had the pigs ears appetizer -- be adventurous and try it. If you didn't know, you'd think...More

Thank Rachael D
Reviewed October 31, 2017 via mobile

Ate here at the recommendation of my daughter, this is a must try. Away from the bustle of downtown, which was perfect. We did the special, two dinners for $80 and was not disappointed. Server was super attentive, friendly, and knew when to give us...More

Thank Dave W
Reviewed October 26, 2017 via mobile

We had the great pleasure of celebrating my wife’s birthday here at Rx. They printed menus with a happy birthday wish for my wife, what a great way to start a meal😀 The menu offered tonight had nice choices of appetizers and main dishes My...More

Thank Bill T
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Questions & Answers
Cynthia F
January 18, 2015|
Response from Betsy V | Reviewed this property |
A wicked good pork belly, grits and egg dish...a twisted Monte Cristo... Eggs Benedict...buscuits and housemade peach jam, lots more...
Cynthia F
January 18, 2015|
Response from Betsy V | Reviewed this property |
Small compared to other varieties/areas I have sampled. But the minionette on the raw ones is inspired....
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Restaurant Details

Rating summary
  • Food
  • Value
Average prices
$30 - $30
Dinner, Lunch, Brunch, Late Night
Restaurant features
Reservations, Seating, Waitstaff, Wheelchair Accessible, Serves Alcohol, Full Bar
Dining Style
Casual Elegant
Good for
Romantic, Bar scene, Local cuisine, Families with children, Business meetings, Special occasions
Open Hours
10:00 AM - 10:00 PM
5:00 PM - 10:00 PM
5:00 PM - 10:00 PM
5:00 PM - 10:00 PM
5:00 PM - 10:30 PM
5:00 PM - 10:30 PM
Location and Contact Information
  • Address: 421 Castle St, Wilmington, NC 28401-5141
  • Location: United States  >  North Carolina (NC)  >  North Carolina Coast  >  Wilmington
  • Phone Number: +1 910-399-3080
  • E-mail
Located in the old Hall's Drugstore on 5th and Castle
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