We noticed that you're using an unsupported browser. The TripAdvisor website may not display properly.
We support the following browsers:
Windows: Internet Explorer, Mozilla Firefox, Google Chrome. Mac: Safari.
Want the lowest hotel prices? You're in the right place. We check 200+ sites for you.

121 Artisan Bistro

$$ - $$$
Map updates are paused. Zoom in to see updated info.
Reset zoom
Updating Map...
Get directions
121 Doctor Michael Debakey Dr, Lake Charles, LA 70601-5950
+1 337-310-7499
11:00 am - 9:30 pm
Closed now
See all hours
Mon - Thu 11:00 am - 9:30 pm
Fri - Sat 11:00 am - 10:00 pm
More Info
Add Photo Write a Review

100 Reviews from our TripAdvisor Community

Traveler rating
Traveler type
Time of year
Showing 100: English reviews
Sulphur, Louisiana
Level Contributor
71 reviews
45 restaurant reviews
common_n_restaurant_reviews_1bd8 13 helpful votes
5 of 5 bubbles Reviewed 2 days ago NEW

My husband and I had the BEST dinner last night at 121. Started with the calamari and crusted shrimp appetizer recommended by the waiter. Strawberry lemon drop martini hit the spot for a pre-meal cocktail. The Mona Lisa pasta dish is always my go-to and it did not disappoint. We had dinner elsewhere the night before and it was awful.... More 

Thank Melissa T
United States
Level Contributor
18 reviews
12 restaurant reviews
5 of 5 bubbles Reviewed January 15, 2017

All I can say is order their Martini's. Any flavor. The Mona Lisa, ceaser salad, and for desert, the bread pudding with rum sauce. YUM......MY! Fabulous Italian restaurant.

Thank Melinda M
Tuscaloosa, Alabama
Level Contributor
293 reviews
194 restaurant reviews
common_n_restaurant_reviews_1bd8 93 helpful votes
4 of 5 bubbles Reviewed January 4, 2017 via mobile

Very good atmosphere- crab and shrimp bisque was good but not hot enough when served- had an excellent spinach salad with chicken- done well and very tasty. Felt food was on the pricey side and service was average.

Thank Kwajkid007
Level Contributor
328 reviews
215 restaurant reviews
common_n_restaurant_reviews_1bd8 98 helpful votes
2 of 5 bubbles Reviewed December 17, 2016

No call ahead seating... no problem. We were told it was worth the wait. Holiday season=lots of folks eating out and celebrating. But come on!! Who would know if the food was good, we were never seated. We waited almost 45 minutes, and finally left after the fourth party was seated ahead of us. It seemed that those seated ahead... More 

Thank ladybugtx76
Lake Charles, Louisiana
2 reviews
2 of 5 bubbles Reviewed December 14, 2016 via mobile

I waited 15 mins and never saw a server. I finally had to wave someone down and she graciously took care of me. The food is good.

Thank rebeccacS6948DB
Level Contributor
21 reviews
16 restaurant reviews
5 of 5 bubbles Reviewed December 8, 2016

Good atmosphere, food is delicious, the staff are courteous, friendly and the service was great. It's good for lunch or dinner, families as well as for business.

Thank Nina R
Marksville, LA
Level Contributor
238 reviews
132 restaurant reviews
common_n_restaurant_reviews_1bd8 64 helpful votes
5 of 5 bubbles Reviewed November 2, 2016 via mobile

When my calzone came out it was huge! Absolutely delicious! We ate in the bar and service was wonderful. I will be back!

Thank merrudy
Lake Charles, Louisiana
Level Contributor
81 reviews
50 restaurant reviews
common_n_restaurant_reviews_1bd8 31 helpful votes
5 of 5 bubbles Reviewed November 2, 2016

My husband and I had the fried mozzerella and marinara for our appetizer and it was delicious. We each had a ribeye for our entree' and they were both cooked and seasoned perfectly! This was the best steak either of us had eaten in quite a while. Our waiter was friendly and prompt. This was a very pleasant restaurant that... More 

Thank Sherrie1970
Level Contributor
142 reviews
63 restaurant reviews
common_n_restaurant_reviews_1bd8 20 helpful votes
3 of 5 bubbles Reviewed October 25, 2016 via mobile

On biz in lake Charles we went here for dinner and drinks. Good beer and wine. I had eggplant mazzallana, (aubergine, mozzarella , ham and tomato) nice. The others had lamb lollipops (if you like lamb looked good), pizza(ok), Mona Lisa ( pasta with shrimp ) .nice place service so so. If you're in town a good place for a... More 

Thank Stevey1631
Monroe, New Jersey
Level Contributor
7 reviews
5 restaurant reviews
4 of 5 bubbles Reviewed October 18, 2016

Food was excellent and the service was great. We had a large party and they were accommodating with food and drinks coming out at the same time. No issues with quality of the food

Thank jilll0ng

Travelers who viewed 121 Artisan Bistro also viewed

Lake Charles, LA
Lake Charles, LA

Been to 121 Artisan Bistro? Share your experiences!

Write a Review Add Photos & Videos

Is This Your TripAdvisor Listing?

Own or manage this property? Claim your listing for free to respond to reviews, update your profile and much more.

Claim Your Listing
Improve this listing

Restaurant Details

Rating summary
  • Food
    4.5 of 5 bubbles
    4 of 5 bubbles
  • Value
    4 of 5 bubbles
    4.5 of 5 bubbles
Italian, American
Lunch, Dinner
Restaurant features
Seating, Waitstaff, Parking Available, Wheelchair Accessible, Serves Alcohol, Full Bar, Takeout, Reservations, Television
Good for
Families with children, Special occasions, Bar scene, Kids, Business meetings
Open Hours
11:00 am - 9:30 pm
11:00 am - 9:30 pm
11:00 am - 9:30 pm
11:00 am - 9:30 pm
11:00 am - 10:00 pm
11:00 am - 10:00 pm
Location and Contact Information
  • Address: 121 Doctor Michael Debakey Dr, Lake Charles, LA 70601-5950
  • Location: United States  >  Louisiana (LA)  >  Lake Charles
  • Phone Number: +1 337-310-7499

Questions & Answers

Here's what previous visitors have asked, with answers from representatives of 121 Artisan Bistro and other visitors
1 question
Ask a question
Questions? Get answers from 121 Artisan Bistro staff and past visitors.
Posting guidelines
Typical questions asked:
  • Do you have gluten-free options?
  • Is there a dress code?
  • Do you allow dogs on the outdoor patio?