We noticed that you're using an unsupported browser. The TripAdvisor website may not display properly.We support the following browsers:
Windows: Internet Explorer, Mozilla Firefox, Google Chrome. Mac: Safari.
Clear all
Your Selections
  Free Wifi Budget Beachfront Luxury City Center Mid-range Breakfast included Pool Romantic Best Value Free Parking Resort Trendy Boutique Family-friendly Charming Quiet Restaurant Pets Allowed Suites Kitchenette Spa Bar/Lounge Airport Transportation Fitness center Quaint Room Service Business Classic Green & up Internet & up Non-Smoking Hotel Business Center & up Clean Hotels Air Conditioning Meeting Rooms Hotels with Restaurants Quiet Hotels Suite Hotels Concierge Downtown Hotels Hotels with Complimentary Breakfast Hotels with Free Wifi Independent Hotels Accessible rooms Modern Hotels Hotels with Balconies Wedding Hotels Hotels with Shuttle Downtown Cheap Hotels Hotels with Bars Charming Hotels Safe Hotels Hotels with Jacuzzi Hotels on the River Hotels with Room Service Hotels with Kitchenette Hotels with Hot Tubs Historic Hotels Honeymoon Hotels Boutique Hotels Heritage Hotels Foodie Spa Hotels Unique Hotels Luxury Traveler History Buff Like a Local Beach Resorts Beach Goer Family Vacationer Luxury Boutique Hotels Peace and Quiet Seeker Hotels with Smoking Rooms Party Hotels Quiet Resorts Family Resorts Shopping Fanatic Art and Architecture Lover Romantic Boutique Hotels Luxury Resorts Nature Lover Thrifty Traveler Trendsetter 60+ Traveler Urban Explorer Hotels with Military Discounts Golf Hotels Spring Break Resorts Thrill Seeker Condo Hotels Convention Hotels Hotels With Indoor Pools Suite Resorts Honeymoon Resorts Historic District - North Condo Resorts Couples Resorts Hotels with Villas Resorts with Jacuzzi Oceanfront Hotels Spa Resorts Golf Resorts Spring Break Hotels Luxury Spa Resorts Hampton Inn Marriott Vacation Club Wedding Resorts Boardwalk Resorts Hotels with Nightclubs Luxury Beach Resorts Eco-tourist Themed Hotels Days Inn Yamacraw Village Vegetarian Apartment Hotels Holiday Inn Express Fairfield Inn Budget Hotels Hilton Garden Inn Boardwalk Hotels Golf course Nightlife Seeker Best Western Cheap Resorts Historic Bed and Breakfast Romantic Bed and Breakfast Fishing Resorts Timeshare Rentals All Inclusive Resorts Timeshare Resorts Hotels With Adjoining Rooms $ $$ $$$ $$$$ Baymont Inn And Suites La Quinta Inn & Suites EconoLodge Motel 6 Suburban Extended Stay Courtyard Hyatt Marriott Autograph Collection Quality Inn Avalon/Oglethorpe Mall Area Comfort Suites Westin Residence Inn Marriott Homewood Suites Springhill Suites Country Inns And Suites Sonesta Hotels And Resorts Kimpton Hotels Intown Suites Americas Best Value Inns Extended Stay America Embassy Suites Hilton Grand Vacations Club Hilton Hotels Holiday Inn Resort Hotel Indigo Clarion Sleep Inn Studio 6 Omni Hotels Hotels with Government Rates Candlewood Suites Hotels with Weekly Rates Staybridge Suites DoubleTree Holiday Inn The Walt Disney Company Romantic Resorts Towneplace Suites Ramada Red Roof Inns Cheap Motels WoodSpring Suites Preferred Hotels & Resorts Within 10 mi Within 25 mi
Price per night
Enter dates & see best prices
to
Amenities
More
Amenities
Location
Any Distance
from
Traveler Rating
Hotel class
Style
More
Style
Hotel brand
More
Hotel brand
  • Sort by:
  • Traveler Ranked
  • Best Value
  • Lowest Price
  • Distance
TripAdvisor members only.
Login for exclusive access to hotel deals up to 40% off
Login to get best prices
Royal Palm Motel
0.2 miles from Saint James Infirmary
  • Free Parking
  • Pool
Sky Suites
Booking.com
$150
View Deal
0.2 miles from Saint James Infirmary
  • Free Parking
  • Pool
Desoto Beach Hotel
SAVE $88
$273
Expedia.com
$185
View Deal
0.6 miles from Saint James Infirmary
  • Free Wifi
  • Free Parking
Dunes Inn & Suites
No availability for your dates from these sites
0.6 miles from Saint James Infirmary
  • Free Wifi
  • Free Parking
Sandcastle Inn
SAVE $34
$204
Booking.com
$170
View Deal
0.6 miles from Saint James Infirmary
  • Free Wifi
  • Free Parking
Hotel Tybee
SAVE $30
$245
Expedia.com
$215
View Deal
0.7 miles from Saint James Infirmary
  • Free Wifi
  • Free Parking
Admiral's Inn
SAVE $9
$170
Booking.com
$161
View Deal
0.7 miles from Saint James Infirmary
  • Free Wifi
  • Free Parking
Sea & Breeze Hotel
No availability for your dates from these sites
0.8 miles from Saint James Infirmary
  • Free Wifi
  • Free Parking
South Beach Inn
7.9 miles from Saint James Infirmary
  • Free Wifi
  • Free Parking
Marriott's Monarch at Sea Pines
No availability for your dates from these sites
9.1 miles from Saint James Infirmary
  • Free Wifi
  • Free Parking
Marriott's Heritage Club
No availability for your dates from these sites
9.4 miles from Saint James Infirmary
  • Free Wifi
  • Free Parking
No availability for your dates from these sites
9.5 miles from Saint James Infirmary
  • Free Wifi
  • Free Parking
Marriott's Grande Ocean
SAVE $22
$672
Marriott
$650
View Deal
10.5 miles from Saint James Infirmary
  • Free Wifi
  • Free Parking
Ocean Oak Resort by Hilton Grand Vacations
No availability for your dates from these sites
10.7 miles from Saint James Infirmary
  • Free Wifi
  • Free Parking
Best Western Ocean Breeze Inn
SAVE $59
$212
Expedia.com
$153
View Deal
10.8 miles from Saint James Infirmary
  • Free Wifi
  • Free Parking
Metropolitan Hotel Hilton Head
No availability for your dates from these sites
10.8 miles from Saint James Infirmary
  • Free Wifi
  • Free Parking
Holiday Inn Express Hilton Head Island
SAVE $19
$223
HIExpress.com
$204
View Deal
11.0 miles from Saint James Infirmary
  • Free Wifi
  • Free Parking
Beach House, A Holiday Inn Resort
No availability for your dates from these sites
11.1 miles from Saint James Infirmary
  • Free Wifi
  • Free Parking
Brigantine Quarters by EVRentals
12.3 miles from Saint James Infirmary
  • Fitness center
Sonesta Resort Hilton Head Island
SAVE $77
$394
Priceline
$317
View Deal
12.5 miles from Saint James Infirmary
  • Free Wifi
  • Free Parking
Park Lane Hotel and Suites
SAVE $22
$219
Expedia.com
$197
View Deal
12.7 miles from Saint James Infirmary
  • Free Wifi
  • Free Parking
Omni Hilton Head Oceanfront Resort
SAVE $57
$374
AMOMA
$317
View Deal
13.3 miles from Saint James Infirmary
  • Free Wifi
  • Free Parking
Red Roof Inn Hilton Head Island
SAVE $3
$128
Booking.com
$125
View Deal
13.6 miles from Saint James Infirmary
  • Free Wifi
  • Free Parking
Hilton Head Marriott Resort & Spa
SAVE $13
$352
Expedia.com
$339
View Deal
13.7 miles from Saint James Infirmary
  • Free Wifi
  • Pool
Motel 6 Hilton Head
13.7 miles from Saint James Infirmary
  • Free Parking
  • Pool
Days Inn Hilton Head
SAVE $44
$122
AMOMA
$78
View Deal
13.9 miles from Saint James Infirmary
  • Free Wifi
  • Free Parking
Montage Palmetto Bluff
Expedia.com
$340
View Deal
14.0 miles from Saint James Infirmary
  • Free Wifi
  • Free Parking
Marriott's Harbour Point and Sunset Pointe at Shelter Cove
SAVE $14
$413
Expedia.com
$399
View Deal
14.0 miles from Saint James Infirmary
  • Free Wifi
  • Free Parking
Harbourside II
14.1 miles from Saint James Infirmary
  • Pool
Disney's Hilton Head Island Resort
AMOMA
$578
View Deal
14.2 miles from Saint James Infirmary
  • Free Wifi
  • Free Parking
Still looking for a place to stay?
Tybee Island has 8 B&Bs/inns with 1,671 reviews
Surf Song Bed & Breakfast
1.1 miles from Saint James Infirmary
  • Free Wifi
  • Free Parking
Beachview Bed and Breakfast
0.9 miles from Saint James Infirmary
  • Free Wifi
  • Free Parking
DeSoto Beach Bed & Breakfast
0.6 miles from Saint James Infirmary
  • Free Wifi
  • Free Parking
See all 8 Tybee Island B&Bs/inns
See all hotels in or near Tybee Island
South Beach Inn
7.9 miles from Saint James Infirmary
  • Free Wifi
  • Free Parking
Marriott's Monarch at Sea Pines
No availability for your dates from these sites
9.1 miles from Saint James Infirmary
  • Free Wifi
  • Free Parking
No availability for your dates from these sites
9.5 miles from Saint James Infirmary
  • Free Wifi
  • Free Parking
Marriott's Heritage Club
No availability for your dates from these sites
9.4 miles from Saint James Infirmary
  • Free Wifi
  • Free Parking
Marriott's Grande Ocean
SAVE $22
$672
Marriott
$650
View Deal