It seems like every time of year is "in season" in Lenox, a small Berkshire town that has been a popular retreat since the 19th century. In summer, picnic on the lawn at Tanglewood, the Boston Symphony Orchestra's summer home. In fall, when foliage peaks, take to the hiking and biking paths of the Pleasant Valley Sanctuary to immerse yourself in the vibrant colors of the mountains. Winter visitors enjoy skiing at a number of resorts and cross-country trails, and in spring, hikers and golfers practice their pastimes in splendid settings. Rejuvenating treatments and pampering, at the well-known Cranwell Spa, are favored all year long.

A rich 300-year history, a thriving arts community and seemingly endless wilderness make this New York capital city on the Hudson River a great weekend getaway. Outdoor enthusiasts come here to ski, hike, canoe and fish; trout and small-mouth bass fishing is among the best in the U.S. Mountains surround the city, and the tapestry of golds and reds on an autumn day is breathtaking. The city is dominated by an elaborate 10-building complex that includes the State Capitol; the New York State Museum, with life-like dioramas such as American Indian life and an Adirondack logging operation; and the oval-shaped Empire State Performing Arts Center, nicknamed "The Egg." History buffs will enjoy the colonial homes, historic churches and museums, and can tour 18th-century mansions, like the Schuyler, a superb example of pre-Revolutionary War architecture. Whether nature or history is your passion, you'll find an abundance of both in this upstate New York gem.

The Berkshires are home to an impressive collection of cultural and historic sights. Get your fill of music, art and theater at Tanglewood, the Boston Symphony's summer home, MASS MoCA, the country's largest contemporary art center, the Norman Rockwell Museum and the Williamstown Theatre Festival. Recreational opportunities also abound, including snowshoeing, snowboarding, skiing, rafting, kayaking, fishing and golf. The Berkshires are an easy drive, just two and a half hours from Boston and New York.

Westchester County, a collection of towns that serve as a popular suburb for the bordering New York City, is also the gateway to the Hudson River Valley, an area that promises a plethora of outdoor activities, from sailing to bird-watching to cross country skiing. The County also contains Rye Playland, a popular children's amusement park, historic sites from the American Revolution, the African American Heritage Trail and several famous houses, including Lyndhurst, a Gothic Revival mansion.

From its origins as a Connecticut River trading post in 1633, Hartford has become not only the state capital but also the insurance capital of the world, with a slew of historical attractions, a thriving arts and entertainment center, a revitalized riverfront and beautiful parks and public gardens. It was here that the lovable Huck Finn and Tom Sawyer were born in the imagination of celebrated author Mark Twain and immortalized on paper during the writer's Hartford years. Twain's home and those of fellow literary figures Harriet Beecher Stowe and Noah Webster are open to the public. The Wadsworth Atheneum, the oldest public art museum in the U.S., houses Pilgrim-Century furniture, the Amistad collection and a special treasure hunt system to entice kids to explore the museum's works. If your timing is right (end of June, beginning of July), you'll catch the Elizabeth Park rose gardens in bloom, but fall is also great for brilliant leaf colors, and spring yields colorful gardens and blossoming trees. For a bird's-eye view of the city, visit the observation deck of Travelers Tower, where you might also spot two resident falcons.

Saratoga Springs is one of those special getaway spots where everything is just, well, pretty close to perfect. The city's lovely tree-lined streets and grand old Victorians, porch swings swaying and gardens brimming with colorful flora bring to mind a gentler era. World-class horse racing, renowned performing arts and natural springs spas, plus 13 golf courses, 10 museums, a historic battlefield, fabulous boutiques, antiques and restaurants mean there is something for everyone. Relax at the Lincoln Mineral Baths, window shop in town and then it's off to the races. Walk everywhere, it's that kind of place. One of the oldest tourist destinations in the United States, Saratoga offers ample accommodation choices in elegant hotels, historic bed and breakfasts or comfortable inns. The only drawback is you may never want to leave.

Conquering New York in one visit is impossible. Instead, hit the must-sees – the Empire State Building, the Statue of Liberty, Central Park, the Metropolitan Museum of Art – and then explore off the beaten path with visits to The Cloisters or one of the city’s libraries. Indulge in the bohemian shops of the West Village or the fine dining of the Upper West Side. The bustling marketplace inside of Grand Central Station gives you a literal taste of the best the city has to offer.

Whether you’re a high roller or a low-key lounger, Las Vegas has something to suit your vacation taste. Sample fare from top chefs and cornucopian buffets, try your luck at one of the world’s premier casinos, or take in a spectacular show. Just wandering the Strip is enough to get your heart pumping. Once you’ve had enough of the razzle-dazzle, wave hello to the toothy sea life at the Mandalay Bay Shark Reef, hike Red Rock Canyon, or visit the Neon Museum, where old signs take on new life.

Welcoming, tolerant Gran Canaria offers a little something for everyone. Families flock to the water parks and beaches of Puerto Rico. Those seeking peaceful escape scamper to Mogan's quiet fishing villages. Gay visitors crowd the bars, restaurants and beaches of Playa del Ingles. Urban attractions are on offer in Las Palmas. Three highways open up the island for those with a rental car or a bus schedule. Prime sites to visit include Iglesia de San Juan Bautista de Arucas and Palmalitos zoo park.

From Shoreditch’s swaggering style to Camden’s punky vibe and chic Portobello Road, London is many worlds in one. The city’s energy means that no two days are the same. Explore royal or historic sites, tick off landmarks from your bucket list, eat and drink in exclusive Michelin-starred restaurants, enjoy a pint in a traditional pub, or get lost down winding cobbled streets and see what you stumble across – when it comes to London, the possibilities are endless.

Lingering over pain au chocolat in a sidewalk café, relaxing after a day of strolling along the Seine and marveling at icons like the Eiffel Tower and the Arc de Triomphe… the perfect Paris experience combines leisure and liveliness with enough time to savor both an exquisite meal and exhibits at the Louvre. Awaken your spirit at Notre Dame, bargain hunt at the Marché aux Puces de Montreuil or for goodies at the Marché Biologique Raspail, then cap it all off with a risqué show at the Moulin Rouge.

Barcelona feels a bit surreal – appropriate, since Salvador Dali spent time here and Spanish Catalan architect Antoni Gaudí designed several of the city’s buildings. Stepping into Gaudí’s Church of the Sacred Family is a bit like falling through the looking glass - a journey that you can continue with a visit to Park Güell. Sip sangria at a sidewalk café in Las Ramblas while watching flamboyant street performers, then create your own moveable feast by floating from tapas bar to tapas bar.

Rome wasn't built in a day--and you'll need much more than a day to take in this timeless city. The city is a real-life collage of piazzas, open-air markets, and astonishing historic sites. Toss a coin into the Trevi Fountain, contemplate the Colosseum and the Pantheon, and sample a perfect espresso or gelato before spending an afternoon shopping at the Campo de’Fiori or Via Veneto. Enjoy some of the most memorable meals of your life here, too, from fresh pasta to succulent fried artichokes or a tender oxtail stew.