A patchwork of vineyards and olive groves, dotted with whitewashed hill towns and sun-bronzed beaches—Italy’s southern heel has no shortage of photogenic landscapes. There are a few surprises, too, including the baroque city of Lecce and the Itria Valley, with its UNESCO-listed trulli houses.

This former Bedouin fishing village is now a popular tourist destination—especially for serious windsurfers, who'll find some of the best conditions in the world off Dahab's beaches. Long known as a laid-back, backpacker-friendly town, Dahab is becoming more developed, yet retains a casual vibe. Finally, Dahab is also home to the Blue Hole, the world's most dangerous dive site. Only very experienced technical divers should attempt passage through "The Arch" here; if you're a novice diver, stay close to the surface. (Editor's note: Our list was compiled before political unrest prompted many countries to issue travel warnings for Egypt. If you're currently planning a trip to Egypt, please consider the risks and monitor your government's travel alerts.)

Diverse marine life and hundreds of Red Sea coral reef sites make Sharm El Sheikh a magnet for divers and eco-tourists. The tourist economy of this Sinai Peninsula city has grown quite rapidly over the last few decades, resulting in an upcrop of first-class resorts and posh nightlife. The waters of Ras Mohamed National Park are abundant with schools of fish and, oddly, toilets – thanks to the bathroom fixtures being transported by a cargo ship that sank during a 1981 storm.

Thanks to the addition of an international airport in 2001, Marsa Alam is fast becoming a premium tourist destination, especially for scuba divers. The waters here are brimming with marine life and pristine dive sites. Landlubbers, don’t miss the Emerald Mines and the Temple of Seti I at Khanais.

Dubai is a destination that mixes modern culture with history, adventure with world-class shopping and entertainment. Catch a show at the Dubai Opera, see downtown from atop the Burj Khalifa and spend an afternoon along Dubai Creek exploring the gold, textile and spice souks. If you’re looking for thrills, you can float above the desert dunes in a hot air balloon, climb aboard a high-speed ride at IMG Worlds of Adventure or skydive over the Palm Jumeirah.

The Zanzibar Archipelago, located in the Indian Ocean 15 miles off the coast of Tanzania, is a breathtaking spot to escape from the world. You’ll enjoy clear, turquoise-blue water; shallow sandbars perfect for wading; and many small, nearly deserted islands virtually unvisited by tourists. Explore the World Heritage Site of Stone Town, Zanzibar City’s old quarter. Or just go beach to beach between tiny fishing villages—each one's better than the next.

Sprawling tea plantations surround the serene hills of Munnar, which attract adventure travelers hungry for paragliding, treks to Anaimudi (South India's highest peak) and hikes originating at the confluence of three mountain streams. The stone Christ Church, built by the British in 1910, is adorned with renowned works of stained glass, and Eravikulam National Park, about 10 miles away, is home to equally colorful wildlife, including the endangered Nilgiri Tahr (ibex), ruddy mongoose and 120 bird species.

Densely populated and humming with activity at all hours, Dhaka is a city of contrasts between old and new, rich and poor, industry and folk. From the concrete National Parliament House and ultramodern Bashundhara City, the largest shopping mall in South Asia, to the 17th Century Lalbagh Fort and the open markets along the city's side streets, these contrasts vividly shape the city. Visit the many mosques, temples and museums for a taste of Bengali culture and history.