Popular in the late 18th and early 19th century with luminaries such as Strauss, Wagner, Kafke, Freud, Twain and Edward VII, this sprightly spa town is a charming spot. Delicately painted spa houses and hotels tiptoe up the lush, forested mountainsides. One hundred mineral springs with high carbon dioxide and iron content confetti the town and nearby hillsides, many with neat colonnades and stately pavilions. The most famed is the cupola-capped and colonnade-adorned Krizovy pramen.

The Czech Republic's most famed spa destination, Karlovy Vary - or Carlsbad - saw 200 spa houses sprout by the end of the 1500s. The springs in this idyllic, lush, peaceful Tepla valley are said to cure an almanac's worth of metabolic and gastric issues. Visitors still flock to this town of Baroque and Art Nouveau buildings. Five beautiful Colonnades straddle hot springs where visitors try aquatherapy and drink the mineral-rich water. The town also has a respected international film festival.

The bohemian allure and fairytale features of Prague make it a perfect destination for beach-weary vacationers who want to immerse themselves in culture. You could devote an entire day to exploring Prazsky hrad (Prague Castle), then refueling over a hearty dinner at a classic Czech tavern. Spend some time wandering the Old Town Square before heading over to gape at The Old Town Hall and Astronomical Clock. Prague’s best bars are found in cellars, where historic pubs set the scene for a night of traditional tippling.

Known by the German name "Budweis" in the 19th century, the south Bohemian city of Ceske Budejovice has been a center of brewing since the 13th century. The original inspiration for the American version, Budwar or Budweiser beer remains one of the most popular in the country. The vast, beautiful Námesti Otakar II square is the site of stately Renaissance, Gothic and Baroque buildings, including the beautiful 1727 town hall. Buses and trolleys link areas, and cycling paths run through the city.

A gorgeous spot that’s a convenient day trip from Milan, Lake Como recently earned fame as home to Hollywood star George Clooney. But celeb-spotting aside, it’s known for jaw-dropping natural beauty, elegant old villas—and the scenic towns surrounding the lake. Check out Varenna, Bellagio, and Menaggio, which offer great views, historic churches, and water-based activities such as ferries and passenger-only boats.

The second-largest island in Mediterranean after Sicily, Sardinia serves up a lovely blend of sea, sand and history. Thousands of nuraghe (stone buildings) dot the landscape, proof that people have been enjoying the lovely climate here for millennia. From posh Costa Smerelda in the north to medieval Alghero in the northwest to the lively capital of Cagliari in the south, and with many picturesque towns and unspoiled sandy beaches in between, Sardinia’s got a little something for everyone.

Mild ocean breezes, sandy beaches and swaying Torbay Palms give the small English town of Torquay a distinctively Mediterranean feel. More than just a beach spot, Torquay boasts an enormous coastal aviary and the famous Kents Cavern Prehistoric Caves. Agatha Christie spent most of her life here, and the city is now home to multiple film companies. With such a rich literary history, Torquay may be the perfect place to finish writing that novel or screenplay, or just to relax with a good mystery.

Palma, the economic and cultural hub of Majorca, is a delightful base for exploring the island's many gold and white beaches. A former Moorish casbah, or walled city, Palma's Old Town is an appealing maze of narrow streets that are a delight to explore on foot. Hop on the Soller Railway for a 17-mile scenic trip, visit 14th-century Bellver Castle and the museum of contemporary art, and check out the nightlife.

Dubai is a destination that mixes modern culture with history, adventure with world-class shopping and entertainment. Catch a show at the Dubai Opera, see downtown from atop the Burj Khalifa and spend an afternoon along Dubai Creek exploring the gold, textile and spice souks. If you’re looking for thrills, you can float above the desert dunes in a hot air balloon, climb aboard a high-speed ride at IMG Worlds of Adventure or skydive over the Palm Jumeirah.

Want to make your co-workers insanely jealous? Just casually drop "I’m vacationing in the Maldives this year" into conversation, preferably in the dead of winter. Or better yet, go there without mentioning it to anyone—then send them a "Wish you were here!" postcard.