An exclusive resort town long recognized for attracting royalty, Estoril lies less than 20 miles west of Lisbon and is probably best known for its casino. One of Europe’s largest, it was the inspiration for the first of Ian Fleming’s James Bond books, "Casino Royale." Estoril’s mild winters and warm sunny summers make it a perfect beach town, with one of the nicest, Praia do Tamariz, lying right next to the casino. So famous has Estoril become that the local coast is now called Costa do Estoril.

A coastal town just 20 miles west of Lisbon, Cascais was once a small fishing village, but its idyllic scenery attracted the attention of artists, writers and expelled European nobility in the 20th century. Today, it still attracts high society, but all society comes in force to enjoy the gorgeous beaches and adventure options like sailing and surfing. The Conde de Castro Guimarães Museum, a former palace, is now open to the public and displays an impressive collection of art and artifacts.

When 13th-century Portuguese Queen Isabel passed through Obidos and marveled at its beauty, her husband King Denis I simply gave it to her. For centuries after, the kings of Portugal followed suit, presenting the picturesque little town to their queens as a wedding gift. With its white buildings shining as brightly now as then, the walled city of Obidos is very popular with tourists, its hillside location offering amazing views of the Estremadura area. The medieval castle is a main attraction.

Nazare, named after the Biblical “Nazareth” in the 4th century, is Portugal’s most famous fishing village, now becoming important as well in the world of big wave, tow-in surfing. The tallest wave ever recorded being surfed – by a Hawaiian big-wave surfer – was off Nazare.

Time seems to stand still in Evora, a well-preserved medieval town that features protective walls, a 13th-century cathedral, several palaces,and a 1st-century Roman temple. No surprise that the town center is a UNESCO World Heritage Site. Even though it’s kind of creepy, don’t miss the Chapel of Bones, where the remains of nuns and monks are arranged in a haunting mosaic.

From Shoreditch’s swaggering style to Camden’s punky vibe and chic Portobello Road, London is many worlds in one. The city’s energy means that no two days are the same. Explore royal or historic sites, tick off landmarks from your bucket list, eat and drink in exclusive Michelin-starred restaurants, enjoy a pint in a traditional pub, or get lost down winding cobbled streets and see what you stumble across – when it comes to London, the possibilities are endless.

Rome wasn't built in a day--and you'll need much more than a day to take in this timeless city. The city is a real-life collage of piazzas, open-air markets, and astonishing historic sites. Toss a coin into the Trevi Fountain, contemplate the Colosseum and the Pantheon, and sample a perfect espresso or gelato before spending an afternoon shopping at the Campo de’Fiori or Via Veneto. Enjoy some of the most memorable meals of your life here, too, from fresh pasta to succulent fried artichokes or a tender oxtail stew.

This city, full of colorful homes, canals and bridges, is one of Europe's most picturesque capitals. Must-sees on any visitor's itinerary include the Anne Frank House, the Van Gogh Museum and the world's only floating flower market. Rent a bike and join thousands of locals navigating Amsterdam's labyrinthine streets, or just take in the sights on foot. For an unusual and memorable alternative to hotels, consider staying in a houseboat.

Walk the Freedom Trail the first time you visit Boston and you'll quickly get a sense of this coastal city's revolutionary spirit and history. But make sure you also explore some of Boston's fine museums (try the Isabella Stewart Gardner, featuring masterpieces displayed in their collector's mansion) and old neighborhoods (like the North End, Boston's Little Italy). You can't claim to have experienced real Boston culture, though, until you've watched a Red Sox game from the bleachers.

If you're looking for a getaway that's fun for the whole family and easy on your pocket, look no further than Raleigh. With more than 20 free attractions, this stately and energetic capital city offers an affordable way to enjoy history, culture and the good old outdoors. Spend the day hopping between the three state museums of art, history and natural sciences: all offer free admission. Visitors are free to wander around the grounds of the State Capitol, where they can also observe the legislative process. Stroll past the graves of Civil War generals at a historic cemetery or meander along cobblestone streets of City Market. Shop for the greenest broccoli, reddest apples and tastiest homemade treats around at the State Farmers Market. With over 150 parks, lakes and green ways in Raleigh alone, there is ample opportunity to enjoy golf, biking, swimming, boating and other outdoor adventures.

Detroit is an amazing destination for your next weekend getaway. If exploring is your thing, hop on a bike and meet new friends on the Slow Roll bike tour (you’ll find a unique perspective on the city, and the slow pace is perfect for all skill levels). And while you may not think of Detroit as wine country, the newly opened Detroit Vineyards is one of the country’s largest urban wineries, crafting superior wines right in the heart of the city. Grab your glass and make a toast to the weekend!

Dubai is a destination that mixes modern culture with history, adventure with world-class shopping and entertainment. Catch a show at the Dubai Opera, see downtown from atop the Burj Khalifa and spend an afternoon along Dubai Creek exploring the gold, textile and spice souks. If you’re looking for thrills, you can float above the desert dunes in a hot air balloon, climb aboard a high-speed ride at IMG Worlds of Adventure or skydive over the Palm Jumeirah.

Gatlinburg, at the heart of Great Smoky Mountains National Park, is an ideal base for a family looking to explore the park's numerous offerings. After you've gone hiking, fishing, rafting or horseback riding, ride an elevator 342 feet to the top of the Gatlinburg Space Needle for stunning views of the Smokies. There's also an amusement center next door with nifty rides and games.

The windy city is a cornucopia of modern art, fine dining, cutting edge comedy, and die-hard sports fans. Snap a photo of your reflection in the silver Cloud Gate sculpture at Millennium Park before heading to Grant Park to get hit with the refreshing spray of Buckingham Fountain. There are dozens of museums and theater companies in Chicago, so a cultural experience is never hard to find. You’re sure to laugh your head off at the Second City Theater, the professional launch pad of many famous comedians.

Saint Augustine is a luxurious, romantic vacation spot—you’ll find classic hotels and intimate restaurants. Those can be a dime a dozen, though. What sets Saint Augustine apart is its history—it’s the oldest European settlement in the U.S. And nowhere else in the world can you taste the waters of the Fountain of Youth Archeological Park (where Ponce de Leon may have landed). Who knows, if you vacation here, maybe you won’t need that Botox!