Berlin is an edgy city, from its fashion to its architecture to its charged political history. The Berlin Wall is a sobering reminder of the hyper-charged postwar atmosphere, and yet the graffiti art that now covers its remnants has become symbolic of social progress. Check out the Weltzeituhr (world time) Clock, topped by a model of the solar system, then turn back time by dining at the historic Zur Letzten Instanz, a 16th century restaurant that was frequented by Napoleon and Beethoven.

Named by American soldiers during the post-World War II occupation years, the Romantic Road is a 200-mile-plus section of one of Germany's most picturesque highways, stretching from Würzburg in Bavaria's north to Füssen near the Austrian border. Along the route are many favorite tourist towns and attractions, including Rothenburg ob der Tauber, Dinkelsbühl, Augsburg, and Neuschwanstein and Hohenschwangau Castles. Bike tours along the route are quite popular, and bus tours are also available.

Lake Maggiore—one of the largest lakes in Italy—is known for its Alpine splendor, and the resort town of Stresa is a perfectly elegant place to admire its beauty. A quick trip from Milan, the town features opulent villas, pretty piazzas, and the storied Grand Hotel.

Over the centuries, many cultures have added their mark to this prized piece of land. Today, you can experience those influences firsthand by exploring Istanbul’s mahalles (neighborhoods). From the holy sites of Sultanahmet and the 19th-century European elegance of Beyoğlu to the high fashion of Nişantaşı, the vibrant café society of Kadıköy and the football-loving streets of Beşiktaş, it’s easy to see why travelers say that Istanbul isn’t just one city, but many cities within one.

Corsica is a laid-back French island, with a breezy vibe that’s part European weekend and part tropical honeymoon. The port city of Bastia flings its arms wide open to weary travelers disembarking from a long ferry trip. For a truly charming Corsican experience, catch a train through the mountains to the beach, passing by rustic villages and grazing cows along the way. Take a few hours or even a few weeks to explore the island’s famous walking trails, including the varsity-level GR 20.

The museums of Lisbon celebrate the rich history and culture of this Portuguese capital city. The Maritime Museum is perfect for kids (and grown-ups!) who adore all things nautical, while the Casa-Museu Dr. Anastácio Gonçalves is a hidden gem of colorful artwork. To fully appreciate the city’s dramatic stone architecture you can take a guided walking tour, or customize your own tour, making sure to visit the Padrao dos Descobrimentos, the Mosteiro dos Jeronimos, and the UNESCO World Heritage site the Torre de Belem.

The oldest university in the world isn’t Oxford or the Sorbonne—it’s the University of Al-Karaouine, and you’ll find it in Fez el Bali. This walled city, a UNESCO World Heritage Site, will transport you back to medieval times. Visit the ancient maze-like quarters of the Medina to Fez el-Bali and the four imposing Gates of Fez, with their distinctive Moroccan tile work.

Camden, Maine is proud to call itself the "Jewel of the Coast." A beautiful seaport town with a harbor full of sail boats, Camden has been used as the setting for so many movies, from Carousel to Peyton Place, that it is what many people think of when they think of New England. With a series of annual festivals running all year round, including the US Toboggan Championships, the Summer HarborArts Juried Arts & Craft Show and Windjammer Weekend, there is always something to do in Camden.

Visit Provincetown and have a blast enjoying some of Cape Cod’s best beaches (Race Point Beach and Herring Cove Beach are favorites of TripAdvisor travelers). Plenty of cool boutiques, restaurants and art galleries give this town a fun and funky vibe. It’s an exceptionally LGBT-friendly destination as well. One tip: if it’s high season, take the ferry or a quick flight from Boston (unless you enjoy spending hours sitting in traffic).

Detroit is an amazing destination for your next weekend getaway. If exploring is your thing, hop on a bike and meet new friends on the Slow Roll bike tour (you’ll find a unique perspective on the city, and the slow pace is perfect for all skill levels). And while you may not think of Detroit as wine country, the newly opened Detroit Vineyards is one of the country’s largest urban wineries, crafting superior wines right in the heart of the city. Grab your glass and make a toast to the weekend!