Historic Charleston is bursting with Southern charm and hospitality. The city feels a bit like it’s suspended in time, thanks to its antebellum architecture and surrounding plantation landscapes. Take in incredible views of the Battery and the French Quarter as you stroll the Waterfront Park, then become inspired by the cultivated beauty of the gardens at Middleton Place. At night, try a ghost tour for an introduction to the spooky side of the city.

Conquering New York in one visit is impossible. Instead, hit the must-sees – the Empire State Building, the Statue of Liberty, Central Park, the Metropolitan Museum of Art – and then explore off the beaten path with visits to The Cloisters or one of the city’s libraries. Indulge in the bohemian shops of the West Village or the fine dining of the Upper West Side. The bustling marketplace inside of Grand Central Station gives you a literal taste of the best the city has to offer.

New Orleans is full of life—but with a laid-back energy that sets it apart from other cities. You’ll wanna soak it all in: impromptu jazz performances up and down Frenchmen Street, the ding of the St. Charles Streetcar, moss-draped trees in the famous Garden District…even its gothic, above-ground cemeteries. (The city’s said to be one of the most haunted in America.) For some, NOLA will always be all about Bourbon Street, but for travelers looking to take it slow, the city’s distinct blend of cultures—including Creole and Cajun—means there’s tons to see, explore, and yes, eat.

You may have all heard that everything is bigger in Texas. Well, Dallas does its best to fulfill that promise. You'll find several museums with vast art collections and fascinating specialty museums like The Sixth Floor Museum/Texas School Book Depository, which, though small in size, offers an immense amount of information about the assassination of John F. Kennedy. And of course, visit a local steakhouse for a terrific (and enormous) meal.

From the Magic Kingdom to magical spa treatments, Orlando sparkles with the promise of adventure. Spend a day exploring the world-famous Disney theme parks or screaming your head off on a Universal Studios roller coaster. For a less adrenaline-pumping afternoon, enjoy the quiet natural beauty of the Harry P. Leu Gardens or enjoy a seaweed scrub at a luxury day spa. Savor fresh and local ingredients at one of Orlando’s James Beard-nominated restaurants.

Houston hums with an energy and independent spirit all its own. A leading cultural and culinary destination in the South, the city is home to over 11,000 restaurants featuring cuisine from more than 70 countries. The thriving arts scene includes resident opera, ballet, symphony and theater companies. The Museum District houses 19 museums, all within walking distance. Be sure to visit Space Center Houston, where you can visit NASA’s Historic Mission Control at the Johnson Space Center.

Whether you’re a high roller or a low-key lounger, Las Vegas has something to suit your vacation taste. Sample fare from top chefs and cornucopian buffets, try your luck at one of the world’s premier casinos, or take in a spectacular show. Just wandering the Strip is enough to get your heart pumping. Once you’ve had enough of the razzle-dazzle, wave hello to the toothy sea life at the Mandalay Bay Shark Reef, hike Red Rock Canyon, or visit the Neon Museum, where old signs take on new life.

Soaring mountains, jewel-colored lakes and pristine wilderness await you in Canada’s first National Park. The irresistible beauty of the landscape invites travelers to immerse themselves in the outdoors all year round — whether hiking through untouched forests and paddling the turquoise lakes in summertime, or skiing the slopes and soaking in the steamy hot springs during the winter. Travelers also enjoy the warm hospitality of Banff or Lake Louise, the region’s charming mountain townships.

Christopher Columbus added St. Barthelemy, or St. Barts to his collection in 1493, but the French soon stepped in. Today, the chic Caribbean island - officially a department of France - is a popular winter getaway for people from mainland France, the rest of Europe and North America. Keep in shape and walk between attractions or get a rental car to see more of the island. Beachgoers can choose between strands such as Grand Saline, if nude sunbathing appeals, or shady, isolated Colombier Beach.

A gorgeous spot that’s a convenient day trip from Milan, Lake Como recently earned fame as home to Hollywood star George Clooney. But celeb-spotting aside, it’s known for jaw-dropping natural beauty, elegant old villas—and the scenic towns surrounding the lake. Check out Varenna, Bellagio, and Menaggio, which offer great views, historic churches, and water-based activities such as ferries and passenger-only boats.