There’s an Arabic inscription that captures the essence of Granada in a few words: “There is nothing so sad as to be blind in Granada.” The perspicacity of this declaration becomes obvious as soon as you penetrate the austere walls of the Alhambra and take in the full majesty of the architecture, carvings and fountains of the Nasrid palaces. Your ticket (which should be bought well in advance following the instructions on the attraction’s website) also affords entry to the Renaissance Palace of Carlos V and to the exquisite gardens of the Generalife. If you are celebrating a special event, or are in the market for a splurge, you can stay in the lovely Parador, right on site. Make your way down into the city via the atmospheric old quarter of the Albaicin, with its tiny craft shops and restaurants, and head for the Cathedral and Royal Chapel. Also plan a visit to the crypt for the tombs of Ferdinand and Isabella, the instigators of Spain’s imperial adventures to the New World and beyond. It’s worth making the short journey out of town to visit the Monasterio Cartuja, a fabulous Carthusian monastery in the baroque style. Admirers of the poet Lorca should make the effort to visit the Casa-Museo Federico Garcia Lorca in Fuente Vaqueros, about 11 miles from the city centre.

The largest national park in Spain, Sierra Nevada is an outdoor enthusiast’s dream. The rugged terrain includes mountains and gorges made for hiking (Los Cahorros is a favorite with its limestone cliffs and hanging bridges), icy plunge pools for swimming, and plentiful tunnels and caves to explore. Those that aren’t so adventure-inclined can make their own excitement roaming through the many villages dotted throughout Las Alpujarras. The famous Alhambra castle and fortress is also close by, inspiring visitors with its breathtaking architecture and gardens.

Positioned at the eastern tip of the Costa del Sol, Nerja boasts nearly 10 miles of powdery beaches featuring activities like water skiing, scuba diving and sailing. Although tourist-oriented, it hasn't been overtaken by high-rises, and its huge promenade delivers panoramic Mediterranean views.

Malaga is one of the oldest cities in the world, founded in the 8th century by the Phoenicians. Today, art is everywhere-- you can experience exhibits dedicated to glass and crystal, classic cars, contemporary installations, and, of course, the works of Picasso, who was born here. Wander past banana trees and beautiful fountains as you walk through Paseo del Parque, then hit the old city to quench your thirst at a Spanish tavern.

As the gateway to Costa del Sol, Torremolinos is a modern city preserving the great charms of the Andalusian tradition. Here visitors enjoy more than 300 sunny days every year, comfortable temperatures (avg. 19ºC/66ºF) and 7km of beaches along the sparkling Mediterranean. Away from the sea and sand, travelers can explore the old fisherman’s district of “La Carihuela,” or sample the city’s cuisine – including regional favorite Pescalto Frito (fried fish) – in hundreds of restaurants and bars.

Founded by the caliph of Cordoba, this Andalucian city on Spain’s southeast coast is a reminder of the region’s Muslim history. The Alcazaba, a massive fort, dominates the city and affords amazing views. Also worth experiencing are the cathedral and the Almeria Museum. East of the city is the rugged, desolate Cabo de Gata-Nijar coast, a protected area. To the west is the resort area of Roquetas de Mar, featuring vast beaches.

With miles of sandy coastline, it’s no surprise that Fuengirola is a major draw on Spain's Costa del Sol. But the resort town offers than just beaches—a Moorish castle, immersive bio-zoo, amusement parks, and retail zone provide entertainment for the whole family.

Rome wasn't built in a day--and you'll need much more than a day to take in this timeless city. The city is a real-life collage of piazzas, open-air markets, and astonishing historic sites. Toss a coin into the Trevi Fountain, contemplate the Colosseum and the Pantheon, and sample a perfect espresso or gelato before spending an afternoon shopping at the Campo de’Fiori or Via Veneto. Enjoy some of the most memorable meals of your life here, too, from fresh pasta to succulent fried artichokes or a tender oxtail stew.

From Shoreditch’s swaggering style to Camden’s punky vibe and chic Portobello Road, London is many worlds in one. The city’s energy means that no two days are the same. Explore royal or historic sites, tick off landmarks from your bucket list, eat and drink in exclusive Michelin-starred restaurants, enjoy a pint in a traditional pub, or get lost down winding cobbled streets and see what you stumble across – when it comes to London, the possibilities are endless.

This city, full of colorful homes, canals and bridges, is one of Europe's most picturesque capitals. Must-sees on any visitor's itinerary include the Anne Frank House, the Van Gogh Museum and the world's only floating flower market. Rent a bike and join thousands of locals navigating Amsterdam's labyrinthine streets, or just take in the sights on foot. For an unusual and memorable alternative to hotels, consider staying in a houseboat.

Dubai is a destination that mixes modern culture with history, adventure with world-class shopping and entertainment. Catch a show at the Dubai Opera, see downtown from atop the Burj Khalifa and spend an afternoon along Dubai Creek exploring the gold, textile and spice souks. If you’re looking for thrills, you can float above the desert dunes in a hot air balloon, climb aboard a high-speed ride at IMG Worlds of Adventure or skydive over the Palm Jumeirah.

Walk the Freedom Trail the first time you visit Boston and you'll quickly get a sense of this coastal city's revolutionary spirit and history. But make sure you also explore some of Boston's fine museums (try the Isabella Stewart Gardner, featuring masterpieces displayed in their collector's mansion) and old neighborhoods (like the North End, Boston's Little Italy). You can't claim to have experienced real Boston culture, though, until you've watched a Red Sox game from the bleachers.

If you're looking for a getaway that's fun for the whole family and easy on your pocket, look no further than Raleigh. With more than 20 free attractions, this stately and energetic capital city offers an affordable way to enjoy history, culture and the good old outdoors. Spend the day hopping between the three state museums of art, history and natural sciences: all offer free admission. Visitors are free to wander around the grounds of the State Capitol, where they can also observe the legislative process. Stroll past the graves of Civil War generals at a historic cemetery or meander along cobblestone streets of City Market. Shop for the greenest broccoli, reddest apples and tastiest homemade treats around at the State Farmers Market. With over 150 parks, lakes and green ways in Raleigh alone, there is ample opportunity to enjoy golf, biking, swimming, boating and other outdoor adventures.

Detroit is an amazing destination for your next weekend getaway. If exploring is your thing, hop on a bike and meet new friends on the Slow Roll bike tour (you’ll find a unique perspective on the city, and the slow pace is perfect for all skill levels). And while you may not think of Detroit as wine country, the newly opened Detroit Vineyards is one of the country’s largest urban wineries, crafting superior wines right in the heart of the city. Grab your glass and make a toast to the weekend!

Gatlinburg, at the heart of Great Smoky Mountains National Park, is an ideal base for a family looking to explore the park's numerous offerings. After you've gone hiking, fishing, rafting or horseback riding, ride an elevator 342 feet to the top of the Gatlinburg Space Needle for stunning views of the Smokies. There's also an amusement center next door with nifty rides and games.

The windy city is a cornucopia of modern art, fine dining, cutting edge comedy, and die-hard sports fans. Snap a photo of your reflection in the silver Cloud Gate sculpture at Millennium Park before heading to Grant Park to get hit with the refreshing spray of Buckingham Fountain. There are dozens of museums and theater companies in Chicago, so a cultural experience is never hard to find. You’re sure to laugh your head off at the Second City Theater, the professional launch pad of many famous comedians.

Saint Augustine is a luxurious, romantic vacation spot—you’ll find classic hotels and intimate restaurants. Those can be a dime a dozen, though. What sets Saint Augustine apart is its history—it’s the oldest European settlement in the U.S. And nowhere else in the world can you taste the waters of the Fountain of Youth Archeological Park (where Ponce de Leon may have landed). Who knows, if you vacation here, maybe you won’t need that Botox!