Known by the German name "Budweis" in the 19th century, the south Bohemian city of Ceske Budejovice has been a center of brewing since the 13th century. The original inspiration for the American version, Budwar or Budweiser beer remains one of the most popular in the country. The vast, beautiful Námesti Otakar II square is the site of stately Renaissance, Gothic and Baroque buildings, including the beautiful 1727 town hall. Buses and trolleys link areas, and cycling paths run through the city.

Despite its baroque architecture and historic old town, Linz is strikingly contemporary. The northern city hosts a cutting-edge cultural scene, exemplified by its futuristic electronic arts center and glass-fronted modern arts museum, both set on the banks of the Danube River.

Known as Dreiflüssestadt (City of Three Rivers), Passau is the place where the Danube meets the Inn and the Ilz. The picturesque city lies in Germany’s far southeast corner near the Austrian border. Settled since prehistory and a former hub of the salt trade, it became the Roman village of Batavis, then later the Holy Roman Empire’s largest diocese and a sword-making center. Saint Stephan’s Cathedral, home of the world’s second-largest cathedral organ, is one of Passau’s favorite attractions.

The achingly beautiful Tuscany region of Italy is a touchstone of art, food, and culture. Made up of stunning countryside and distinguished cities, Tuscany is the perfect escape for gastronomes, cognoscenti, and fans of the Italian Renaissance. Visit the stunning Roman Catholic cathedrals and galleries of Florence and Arezzo, or make your way to Pisa to see its hallmark Leaning Tower. A bike tour through olive groves and vineyards is a popular way to literally breathe in the Tuscan atmosphere.

This city, full of colorful homes, canals and bridges, is one of Europe's most picturesque capitals. Must-sees on any visitor's itinerary include the Anne Frank House, the Van Gogh Museum and the world's only floating flower market. Rent a bike and join thousands of locals navigating Amsterdam's labyrinthine streets, or just take in the sights on foot. For an unusual and memorable alternative to hotels, consider staying in a houseboat.

Attracting visitors from all parts of the world, Majorca is a dreamy island destination in the Mediterranean Sea, just off the south-east coast of Spain. There's something for every taste—beaches and coves, a spectacular mountain range, romantic fishing villages and a rustic countryside dotted with almond and olive groves.

Palma, the economic and cultural hub of Majorca, is a delightful base for exploring the island's many gold and white beaches. A former Moorish casbah, or walled city, Palma's Old Town is an appealing maze of narrow streets that are a delight to explore on foot. Hop on the Soller Railway for a 17-mile scenic trip, visit 14th-century Bellver Castle and the museum of contemporary art, and check out the nightlife.

Malaga is one of the oldest cities in the world, founded in the 8th century by the Phoenicians. Today, art is everywhere-- you can experience exhibits dedicated to glass and crystal, classic cars, contemporary installations, and, of course, the works of Picasso, who was born here. Wander past banana trees and beautiful fountains as you walk through Paseo del Parque, then hit the old city to quench your thirst at a Spanish tavern.

Welcoming, tolerant Gran Canaria offers a little something for everyone. Families flock to the water parks and beaches of Puerto Rico. Those seeking peaceful escape scamper to Mogan's quiet fishing villages. Gay visitors crowd the bars, restaurants and beaches of Playa del Ingles. Urban attractions are on offer in Las Palmas. Three highways open up the island for those with a rental car or a bus schedule. Prime sites to visit include Iglesia de San Juan Bautista de Arucas and Palmalitos zoo park.

Travelers and traders have enjoyed Red Sea breezes in the open-minded port of Jeddah for centuries, and the city preserves their traces in its UNESCO-listed historic center. The rest of Jeddah is thoroughly modern, energized with a global mix of pilgrims on their way to nearby Mecca.

The prophet Mohammed's birthplace is Islam's spiritual center and is strictly off-limits to non-Muslims. The pillars of Islam state that all Muslims with the means must undertake Hajj, a pilgrimage to Mecca, once in their lifetime. Those who visit the holy city are rewarded not just by proximity to landmarks and religious sites crucial to the religion, such as the Masjid Al Haram (Holy Mosque), the Mountain of Light, the Black Stone and the Well of Zamzam, but with the forgiveness of all their sins.

Want to make your co-workers insanely jealous? Just casually drop "I’m vacationing in the Maldives this year" into conversation, preferably in the dead of winter. Or better yet, go there without mentioning it to anyone—then send them a "Wish you were here!" postcard.