San Diego embodies laid-back California culture, complete with a Boardwalk, surfing communities, and outstanding Mexican food. Breathe in the fresh ocean air at Sunset Cliffs Natural Park, then gobble down a fresh fish taco at a La Jolla seafood joint. The naval aircrafts at the USS Midway Museum will have you standing at attention. A free Sunday concert at the Spreckels Organ Pavilion is the perfect way to unwind after a Saturday night bar-hop in the thumping Gaslamp Quarter.

Whether you’re a high roller or a low-key lounger, Las Vegas has something to suit your vacation taste. Sample fare from top chefs and cornucopian buffets, try your luck at one of the world’s premier casinos, or take in a spectacular show. Just wandering the Strip is enough to get your heart pumping. Once you’ve had enough of the razzle-dazzle, wave hello to the toothy sea life at the Mandalay Bay Shark Reef, hike Red Rock Canyon, or visit the Neon Museum, where old signs take on new life.

Sunny Cancun has much more to offer than its party-town reputation might suggest. Plenty of gorgeous, drama-free family resorts cater to folks who want to experience the tropical Yucatan climate. There are significant Mayan ruins here, such as El Rey and the Yamil Lu’um, a crumbling tower of pale gray stone. Learn more about this ancient civilization at the Museo Maya de Cancun. For a literal taste of Mexico, take a tour of the Museo Sensorial del Tequila.

Isla Mujeres offers a wide variety of tempting options for beach lovers, and is a relative bargain. Snorkel with tropical fish amid coral reefs, skim the blue waters by kayak or boat, or windsurf along the shores of soft, sandy beaches. On land, you can sunbathe, dine on seafood, dance to Latin rhythms, tour on a moped or belly up to the bar for fresh, delicious drinks.

Destin is located on Florida’s Emerald Coast, which gets its name from its beautiful, clear green water. Beaches here have extremely fine, soft sand, so if you’re a beach-walker or your kids enjoy building sand castles, this could be a great destination for you.

Home to some of the best beaches in America, Clearwater is a great family beach destination. Sure, it’s in Florida, but it’s not Giant Rodent Florida (a.k.a. Orlando) or Crazy Spring Break Florida (a.k.a. Fort Lauderdale). Rather, it’s Calm, Old-Fashioned Florida… which is something worth seeing. Oh, and the weather’s outstanding.

The festive city of San Juan is the perfect place to experience true Puerto Rican culture. Get to know its roots by exploring the vibrant neighborhood of El Viejo San Juan (Old San Juan), which consists mostly of Spanish colonial buildings. Flesh out your self-guided history lesson with a visit to El Castillo San Felipe del Morro, a 16th century citadel that’s a UNESCO World Heritage Site. Then reward yourself with a cooling dip at Luquillo or Carolina Beach, then a tasty tour of the Bacardi rum plant.

The Hawaiian island of Maui is a destination for true nature lovers. The ethereal bamboo forest and churning waterfalls in Haleakala National Park can be explored via the Waimoku Falls Trail. Stretch out on warm, golden sands or hit the surf for an unforgettable windsurfing or snorkeling session. Driving the scenic road to Hana along the island’s northeastern shore will be among the most spectacular journeys of your life. Time stands still at the Hawaiian village of Keanae, definitely worth a visit.

Get the experience of visiting two island colonies in the same 37 square miles. Saint Maarten/Saint Martin's spicy marriage of Caribbean, French and Dutch cultures matches its physical diversity: the island is both urban and untamed, with rain forest-like landscapes, white beaches, and amazing caves and wildlife.