Ten million people call vibrant, passionate, sprawling Bogota home. The energy of this metropolitan heart of Colombia is in part fueled by its hundreds of eclectic and authentic dining hot spots, fantastic wines, and frequent foodie festivals. Ask the locals where they like to eat, then walk off your empanadas and aji with a stroll through the historic district of La Candelaria or during an indulgent shopping adventure on the North Side.

Cape Town glistens at the southern toe of the African continent. Tourist brochure-views at Blaauwberg Beach and Kirstenbosch National Botanical Gardens are within easy driving distance of "The Mother City." The Cape of Good Hope Nature Reserve provides sweeping sea vistas, hiking trails and wildlife encounters. On a more somber note, travelers can visit Robben Island, the prison where Nelson Mandela was held for 27 years.

At the shore in Miami Beach, visitors can swim, surf and jet ski in the warm and crystal-clear Atlantic waters. You can also nap on the white sands, work on a tan or simply watch the beautiful people, especially at South Beach, a favorite of models and celebrities.

Miami is hot hot hot! And it’s not just the sultry weather. Here, the nightlife is scorching, thanks to a strong Latin influence and spicy salsa culture. Dance the noche away in a nightclub, or indulge in a fancy meal at one of the city’s celebrity-owned restaurants. By day, hit the beach of course, or have yourself a walkabout, taking in Miami’s colorful art deco architecture. Grab a Cuban sandwich in Little Havana, then ride the vintage carousel at Virginia Key Beach Park.

Fort Lauderdale’s canals and charm have earned it the nickname “The Venice of America.” The beaches offer 23 miles of golden sand, lively with the spirited antics of happy vacationers. Sail the blue-green waters on a chartered catamaran, or dive beneath the surface to meet-and-greet the local sea life. Shopping and dining al fresco on Las Olas Boulevard is one of Fort Lauderdale’s greatest pleasures, thanks to adorable shops and prime people-watching.

Tampa is a laid-back city with a vibrant arts scene and plenty of opportunities for adventure. Busch Gardens offers thrills for families and risk-averse adrenaline junkies, as does the domed IMAX theater of the Museum of Science and Industry. Spend a day touring Tampa’s many art museums, then cheer on your favorite Tampa Bay team at a home game. Get up close and personal with the majestic lions, tigers, and leopards of the Big Cat Rescue animal sanctuary.

From the Magic Kingdom to magical spa treatments, Orlando sparkles with the promise of adventure. Spend a day exploring the world-famous Disney theme parks or screaming your head off on a Universal Studios roller coaster. For a less adrenaline-pumping afternoon, enjoy the quiet natural beauty of the Harry P. Leu Gardens or enjoy a seaweed scrub at a luxury day spa. Savor fresh and local ingredients at one of Orlando’s James Beard-nominated restaurants.

Historic Charleston is bursting with Southern charm and hospitality. The city feels a bit like it’s suspended in time, thanks to its antebellum architecture and surrounding plantation landscapes. Take in incredible views of the Battery and the French Quarter as you stroll the Waterfront Park, then become inspired by the cultivated beauty of the gardens at Middleton Place. At night, try a ghost tour for an introduction to the spooky side of the city.

Myrtle Beach is all at once a spring break destination, golfing destination, retirement community, and family vacation spot. Take in a foot-stomping show at the Carolina Opry, or cheer on your favorite knight at Medieval Times. Mingle with the fishermen of Springmaid Pier, then stop for ice cream along the boardwalk. Shop and dine at one of the area’s many outdoor entertainment complexes, or simply explore the many beaches of the Grand Strand – all with a personality of their own.

New Orleans is full of life—but with a laid-back energy that sets it apart from other cities. You’ll wanna soak it all in: impromptu jazz performances up and down Frenchmen Street, the ding of the St. Charles Streetcar, moss-draped trees in the famous Garden District…even its gothic, above-ground cemeteries. (The city’s said to be one of the most haunted in America.) For some, NOLA will always be all about Bourbon Street, but for travelers looking to take it slow, the city’s distinct blend of cultures—including Creole and Cajun—means there’s tons to see, explore, and yes, eat.