Lively Antwerp is a hidden gem. Its medieval streets, Renaissance monuments and vibrant nightlife tend to be overshadowed by its reputation as center of the diamond trade and as the world's fifth-largest port. Biking is a popular choice for getting around this stylish Flemish city. See thousands of Old Masters at the Royal Museum and Rubens House. Experience the bustle of life at the Grote Markt. Marvel at the art and architecture of the still unfinished Cathedral of Our Lady, started in 1351.

What could be more romantic and inspiring than a place that looks like a backdrop for a fairy tale? The medieval overtones of Bruges’ cobblestone streets lead to countless historical, architectural and artistic wonders. Marvel at ornate houses lining intricate canals, and understand why this is a favorite destination for all types of travelers. The whole city emanates an appreciation of the past, a love of the present, and enthusiasm for the future. Don’t miss Hof Bladelin, Groeninge Museum, Church of Our Lady, and Belfry and Market Halls.

Lille is an architectural feast with strong Flemish influences from the Grand Place to the basilica of Notre Dame de la Treille to the quiet streets of row houses and gardens. For art buffs, Lille is home to the Musee d'Art Moderne and the Palais des Beaux Arts. Children will enjoy the Parc de Zoologique. Savvy travelers know that Lille has a fine public transit system, making this historical hotspot a pleasure to visit.

Touching Belgium on its west and just a few miles from Germany to the east, Maastricht is the capital of Holland’s southernmost region, Limburg. A town rich in history and culture, Maastricht boasts two wonderful town squares: Vrijthof, with Sint-Servaas Church, Sint-Jan's Cathedral and many bars, cafes and restaurants; and Markt, home to the town hall and, on Wednesday and Friday mornings, a fantastic vendor market. The city’s Vestigingswerken, or old town fortifications, are another big draw.

As Belgium’s largest coastal outpost, Ostend offers a rare taste of Flemish beach culture. Inland visitors flock to sandy beaches and the seaside promenade, while reminders of the city’s military and maritime history run deep in the old harbor town.

Holland's most modern city began as a fishing village in the 13th century. It was developing into an industrial and trading power when German bombers destroyed the city center and harbor in 1940. However, Rotterdam's unique architecture now brings many visitors to bike around this urbane, cosmopolitan city. Old Dutch-style houses can still be found in historic Delfshaven, from where the pilgrims set sail in 1620. Cultural offerings from summer's carnival to classical music give Amsterdam competition.

The prophet Mohammed's birthplace is Islam's spiritual center and is strictly off-limits to non-Muslims. The pillars of Islam state that all Muslims with the means must undertake Hajj, a pilgrimage to Mecca, once in their lifetime. Those who visit the holy city are rewarded not just by proximity to landmarks and religious sites crucial to the religion, such as the Masjid Al Haram (Holy Mosque), the Mountain of Light, the Black Stone and the Well of Zamzam, but with the forgiveness of all their sins.

Walk the Freedom Trail the first time you visit Boston and you'll quickly get a sense of this coastal city's revolutionary spirit and history. But make sure you also explore some of Boston's fine museums (try the Isabella Stewart Gardner, featuring masterpieces displayed in their collector's mansion) and old neighborhoods (like the North End, Boston's Little Italy). You can't claim to have experienced real Boston culture, though, until you've watched a Red Sox game from the bleachers.

Conquering New York in one visit is impossible. Instead, hit the must-sees – the Empire State Building, the Statue of Liberty, Central Park, the Metropolitan Museum of Art – and then explore off the beaten path with visits to The Cloisters or one of the city’s libraries. Indulge in the bohemian shops of the West Village or the fine dining of the Upper West Side. The bustling marketplace inside of Grand Central Station gives you a literal taste of the best the city has to offer.

With live music to be heard all across town, 24/7, 365 days a year, Music City lives up to its name. From honky-tonk bands jamming at Tootsie’s Orchid Lounge to songwriters in the round at the Bluebird Cafe and country music legends rocking the Grand Ole Opry, you never know who you might see. The creative spirit from Nashville's music landscape flows into the area's myriad art galleries, up-and-coming fashion scene, historic landmarks and chef-driven restaurants.

Cape Canaveral and the neighboring Kennedy Space Center have become synonymous with space travel in the U.S. The first phases of the U.S. space program were conducted at Cape Canaveral Air Force Station, now a historic landmark and home to the Air Force Space and Missile Museum, before operations were moved to Kennedy. In addition to its Space Coast reputation, Canaveral also boasts the historic Cape Canaveral Lighthouse, Merritt Island National Wildlife Refuge and Canaveral National Seashore.

From the Magic Kingdom to magical spa treatments, Orlando sparkles with the promise of adventure. Spend a day exploring the world-famous Disney theme parks or screaming your head off on a Universal Studios roller coaster. For a less adrenaline-pumping afternoon, enjoy the quiet natural beauty of the Harry P. Leu Gardens or enjoy a seaweed scrub at a luxury day spa. Savor fresh and local ingredients at one of Orlando’s James Beard-nominated restaurants.

Covering nearly 47 square-miles, the Walt Disney World Resort features four theme parks: Epcot, Magic Kingdom Park, Disney’s Animal Kingdom Park and Disney's Hollywood Studios, two water parks: Disney's Blizzard Beach and Disney's Typhoon Lagoon and over 20 resort hotels. With interactive rides, animal adventures, magical attractions, dining, shopping and nearly 60,000 cast members performing in more than 3,000 different roles, guests will be sure to feel the magic of Disney during each and every visit.

Fort Lauderdale’s canals and charm have earned it the nickname “The Venice of America.” The beaches offer 23 miles of golden sand, lively with the spirited antics of happy vacationers. Sail the blue-green waters on a chartered catamaran, or dive beneath the surface to meet-and-greet the local sea life. Shopping and dining al fresco on Las Olas Boulevard is one of Fort Lauderdale’s greatest pleasures, thanks to adorable shops and prime people-watching.

Tampa is a laid-back city with a vibrant arts scene and plenty of opportunities for adventure. Busch Gardens offers thrills for families and risk-averse adrenaline junkies, as does the domed IMAX theater of the Museum of Science and Industry. Spend a day touring Tampa’s many art museums, then cheer on your favorite Tampa Bay team at a home game. Get up close and personal with the majestic lions, tigers, and leopards of the Big Cat Rescue animal sanctuary.

Miami is hot hot hot! And it’s not just the sultry weather. Here, the nightlife is scorching, thanks to a strong Latin influence and spicy salsa culture. Dance the noche away in a nightclub, or indulge in a fancy meal at one of the city’s celebrity-owned restaurants. By day, hit the beach of course, or have yourself a walkabout, taking in Miami’s colorful art deco architecture. Grab a Cuban sandwich in Little Havana, then ride the vintage carousel at Virginia Key Beach Park.