Home to two of America's most prestigious universities, Cambridge exudes a certain intellectual quirkiness. A mix of historical haunts, student hang-outs, alternative art and culture venues, vintage clothing shops, bookstores and ethnic restaurants, the city is, well, really cool. Although it is located just across the Charles River from Boston, Cambridge has a distinct vibe that is noticeable immediately. Start at Harvard Square, a hub of activity and mishmash of trendy stores, outdoor cafes and colorful local characters. Pick up a walking tour map at the visitors information booth in the center of the Square. The route will take you past many important landmarks including the Mount Auburn Cemetery, Tory Row and the Longfellow National Historic Site. Harvard University offers student-led tours through the illustrious buildings and monuments of its sprawling campus. Art and architecture buffs should meander around the M.I.T campus, which includes outdoor sculptures by masters such as Picasso and 20th-century buildings designed by modern greats like Eero Saarinen and I. M. Pei. Along the way, browse through bookstores, stop to watch street performers and grab a coffee at an outdoor café to take in all this captivating city has to offer.

Providence seamlessly blends the old and the new with historic attractions, museums and theaters situated alongside more recent additions like the scenic RiverWalk, outdoor skating center, downtown mall, convention center, hotels and acclaimed restaurants. Wander back in time while strolling down historic Benefit Street or explore Roger Williams Park Zoo with the kids. Tantalize your taste buds on Federal Hill or tour the city from a unique perspective on an authentic Venetian gondola.

Don your walking shoes, breathe in the ocean air and set out to discover this picturesque maritime town. You can join one of several organized walking tours or explore on your own. Portsmouth is filled with old homes and museums, and you'll have your pick of fascinating historic sites. Climb aboard the USS Albacore, a retired U.S. Navy submarine offering tours and exhibits. View an 18th-century garden, striking stairway and period furniture at the Moffatt Ladd House, the home of William Whipple, a signer of the Declaration of Independence, or follow a costumed guide through the John Paul Jones House, home of the Revolutionary War naval hero. For a broader look at the city's history, visit Strawbery Banke Museum, where over 40 buildings have been assembled to depict Portsmouth life from 1695 to 1950, complete with costumed actors. If you know architecture, Portsmouth's array of Colonial, Federalist and Neo-classical styles will dazzle you. Weary of walking? Sit down for a meal at one of Portsmouth's fine eateries or relax on a narrated harbor or whale-watching cruise.

The Atlantic crashes on a coastline strewn with quaint harbors, windswept beaches, glorious dunes and blinking lighthouses. Explore Cape Cod National Seashore, bike past cranberry bogs on the Rail Trail or saunter around Sandwich, the Cape's oldest town. Many areas are architectural and culinary gems - full of weathered shingles, whaling captains' mansions, chowder shacks and upscale dining delights. Don't miss Woods Hole Oceanquest, famed Martha's Vineyard or charmingly upbeat Provincetown.

Here in the heart of Rhode Island’s “Classic Coast,” you can choose your own adventure. Soak in miles of spectacular coastal scenery, study authentic Colonial and Gilded Age architecture, saunter along the wharves of the bustling waterfront, and sink your toes into the sand of stunning beaches. You can be inspired at the legendary mansions, be energized by the vibrant nightlife, and savor local flavor at our many celebrated restaurants, wineries and breweries.

With live music to be heard all across town, 24/7, 365 days a year, Music City lives up to its name. From honky-tonk bands jamming at Tootsie’s Orchid Lounge to songwriters in the round at the Bluebird Cafe and country music legends rocking the Grand Ole Opry, you never know who you might see. The creative spirit from Nashville's music landscape flows into the area's myriad art galleries, up-and-coming fashion scene, historic landmarks and chef-driven restaurants.

From the Magic Kingdom to magical spa treatments, Orlando sparkles with the promise of adventure. Spend a day exploring the world-famous Disney theme parks or screaming your head off on a Universal Studios roller coaster. For a less adrenaline-pumping afternoon, enjoy the quiet natural beauty of the Harry P. Leu Gardens or enjoy a seaweed scrub at a luxury day spa. Savor fresh and local ingredients at one of Orlando’s James Beard-nominated restaurants.

Fort Lauderdale’s canals and charm have earned it the nickname “The Venice of America.” The beaches offer 23 miles of golden sand, lively with the spirited antics of happy vacationers. Sail the blue-green waters on a chartered catamaran, or dive beneath the surface to meet-and-greet the local sea life. Shopping and dining al fresco on Las Olas Boulevard is one of Fort Lauderdale’s greatest pleasures, thanks to adorable shops and prime people-watching.

Miami is hot hot hot! And it’s not just the sultry weather. Here, the nightlife is scorching, thanks to a strong Latin influence and spicy salsa culture. Dance the noche away in a nightclub, or indulge in a fancy meal at one of the city’s celebrity-owned restaurants. By day, hit the beach of course, or have yourself a walkabout, taking in Miami’s colorful art deco architecture. Grab a Cuban sandwich in Little Havana, then ride the vintage carousel at Virginia Key Beach Park.

Have you ever wanted to experience elevated city life? Then step on up to The Mile High City! Denver gives you the best of both worlds with mountain adventures and city excitement. Access to the majestic Rocky Mountains is a breeze and only an hour drive away, making Denver your perfect basecamp. During your stay, check out the award-winning dining scene with 26 Michelin-rated restaurants that will have you dining like a star. But, the fun doesn’t stop there! With a thriving and diverse arts and culture scene, live music at bucket-list concert venues, and championship level professional sports, you can truly do it all in Denver. Elevate your next getaway, and find Mile High City recommendations below!

Whether you’re a high roller or a low-key lounger, Las Vegas has something to suit your vacation taste. Sample fare from top chefs and cornucopian buffets, try your luck at one of the world’s premier casinos, or take in a spectacular show. Just wandering the Strip is enough to get your heart pumping. Once you’ve had enough of the razzle-dazzle, wave hello to the toothy sea life at the Mandalay Bay Shark Reef, hike Red Rock Canyon, or visit the Neon Museum, where old signs take on new life.

In Seattle you simply can’t skip the Central Public Library – a modern architectural marvel of glass grids, unusual shapes, and a “book spiral” that climbs four stories. Stroll over to Pike Place Market to visit the original Starbucks and play catch with a fishmonger. In the heart of the city lies Chihuly Garden and Glass, which will dazzle you with its colorful and delicate works. Glide to the top of the Space Needle for panoramic views of the surrounding mountain ranges and Puget Sound.

Known as the home of “the happiest place on Earth,” there’s more to Anaheim than thrilling theme parks. Bring your appetite to the Anaheim Packing District and Center Street Promenade for some eclectic eateries and award-winning craft breweries. Explore the latest exhibits at the Muzeo Museum and Cultural Center. Enjoy live music at the all-new House of Blues, now at the Anaheim GardenWalk.

Hollywood beckons to tourists who long for a brush with Tinseltown glamor. Tour movie studios, slip your hands into the famous prints at the TCL Chinese Theatre, or indulge in a celeb sighting at one of LA’s white-hot nightspots. Spot your favorite star while shopping at The Grove, or forget all about the famous eye candy as you take in the iconic artwork at The Getty Center. For a different type of star-gazing, peek through the telescopes at the Griffith Observatory.